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Modulation of the caveolin-3 and Akt status in caveolae by insulin resistance in H9c2 cardiomyoblasts

Ha H, Pak Y

  • KMID: 1056228
  • Exp Mol Med.
  • 2005 Jun;37(3):169-178.
We investigated glucose uptake and the translocation of Akt and caveolin-3 in response to insulin in H9c2 cardiomyoblasts exposed to an experimental insulin resistance condition of 100 nM insulin in...
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Versatile Functions of Caveolin-1 in Aging-related Diseases

Nguyen KC, Cho KA

Caveolin-1 (Cav-1) is a trans-membrane protein that is a major component of the caveolae structure on the plasma membrane. Cav-1 is involved in the regulation of various cellular processes, including...
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Effect of Oxidized LDL on the Amount of Insulin Receptor and Gi-proteins in the Caveolae of Bovine Aortic Endothelial Cells (BAEC)

Jeon SY, Son HS, Lee JM, Moon SD, Yoon KH, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 2010071
  • J Korean Diabetes Assoc.
  • 2001 Feb;25(1):71-82.
BACKGROUND AND AIMS: Oxidized LDL (ox-LDL) may induce endothelial cell dysfunction and suggested to have an association with atherosclerosis or insulin resistance. Several studies have shown that ox-LDL inhibits signaling...
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Modulation of the caveolin-3 localization to caveolae and STAT3 to mitochondria by catecholamine-induced cardiac hypertrophy in H9c2 cardiomyoblasts

Jeong K, Kwon H, Min C, Pak Y

We investigated the effect of phenylephrine (PE)- and isoproterenol (ISO)-induced cardiac hypertrophy on subcellular localization and expression of caveolin-3 and STAT3 in H9c2 cardiomyoblast cells. Caveolin-3 localization to plasma membrane...
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Ectopic Expression of Caveolin-1 Induces COX-2 Expression in Rabbit Articular Chondrocytes via MAP Kinase Pathway

Kim SJ

BACKGROUND: Caveolin-1 is a principal component of caveolae membranes in vivo. Although expression of caveolae structure and expression of caveolin family, caveolin-1, -2 and -3, was known in chondrocytes, the...
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Expression of Caveolin-1 in the Differentiated Vestibular Cell Line (UB/UE-1) after Gentamicin Toxicity

Cho BH, Kim KS, Kim MW, Kim MS, Park BR

  • KMID: 2328955
  • J Korean Bal Soc.
  • 2005 Dec;4(2):243-249.
BACKGROUND AND OBJECTIVES: The caveolin is known as a mediator of cell death or survival of injured cell and inhibitor of various signaling pathways. We examined expression of caveolin-1 involved...
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Expression of Caveolin-3 in the Muscle Cell and Tissue

Kwon BS, Lee SJ, Hyun JK, Jun DJ, Joo HW, Kim BH, Shin DH

  • KMID: 2323855
  • J Korean Acad Rehabil Med.
  • 2003 Jun;27(3):382-387.
OBJECTIVE: Caveolae are the microdomain of the plasma membrane that have been implicated in signal transduction and caveolin is a principal component of the caveolae. Caveolin-3, a family of caveolin...
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Association of rOAT1 with Caveolin-1 in Rat Kidney

Cha SH, Won YJ, Hwang JS, Suh CK

  • KMID: 2253308
  • Korean J Nephrol.
  • 2008 Mar;27(2):175-185.
PURPOSE: A family of organic anion transporters (OAT) has been identified, and several isoforms have been reported. The regulatory mechanisms of OATs functions, however, still remain to be elucidated. The...
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Rat Organic Anion Transporter 3 Co-localized with Caveolin-2 in Rat Kidney

Kim HW, Kwak JO, Kim MJ, Lee SW, Jung SM, Gwak HK, Cha SH

  • KMID: 2079491
  • Korean J Nephrol.
  • 2005 Jul;24(4):537-548.
BACKGROUND: The recently identified organic anion transporter 3 (rOAT3) was mainly expressed in kidney, liver and brain tissue, and it contributes the movement of endogenous or exogenous substances across the...
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Evidence for Cyclooxygenase-2 Association with Caveolin-3 in Primary Cultured Rat Chondrocytes

Kwak JO, Lee WK, Kim HW, Jung SM, Oh KJ, Jung SY, Huh YH, Cha SH

The purpose of this study was to demonstrate the cellular localization of cyclooxygenase-2 (COX-2) and caveolin-3 (Cav-3) in primarily cultured rat chondrocytes. In normal rat chondrocytes, we observed relatively high...
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Leiomyosarcoma of the Skin: Report of A Case

Yoo YE, Chung TB, Hwang SW, Chun IK, Kim YP

  • KMID: 2231756
  • Korean J Dermatol.
  • 1983 Apr;21(2):225-229.
Leiomyosarcoma arising in the skin is rare tumor, and diagnosis usually is made microscopically. After local excision, these lesions recur in large proportion of pat ients. The authors herein report...
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Introduction of Organic Anion Transporters (SLC22A) and a Regulatory Mechanism by Caveolins

Lee WK, Jung SM, Kwak JO, Cha SH

The kidney is an important organ for controlling the volume of body fluids, electrolytic balance and excretion/reabsorption of endogenous and exogenous compounds. Among these renal functions, excretion/reabsorption of endogenous and...
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Clathrin and Lipid Raft-dependent Internalization of Porphyromonas gingivalis in Endothelial Cells

Kim SY, Kim SH, Choi EK, Paek YW, Kang IC

  • KMID: 1727430
  • Int J Oral Biol.
  • 2014 Sep;39(3):131-136.
Porphyromonas gingivalis is one of the most important periodontal pathogens and has been to known to invade various types of cells, including endothelial cells. The present study investigated the mechanisms...
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Cholesterol, a Major Component of Caveolae, Down-regulates Matrix Metalloproteinase-1 Expression through ERK/JNK Pathway in Cultured Human Dermal Fibroblasts

Kim S, Han J, Lee DH, Cho KH, Kim KH, Chung JH

BACKGROUND: Cholesterol is a major component of specialized membrane microdomains known as lipid rafts or caveolae, which modulate the fluidity of biological membranes. Membrane cholesterol therefore plays an important role...
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A Study on Morphological and Immunohistochemical Changes of the Myometrium in the Pregnant and Postpartum Rat

Han HD, Yang YC, Bae KW

  • KMID: 1530294
  • Korean J Anat.
  • 1998 Dec;31(6):905-922.
This experiment was performed to investigate morphological and immunohistochemical changes of the connective tissue, the nerve and the smooth muscle cell in the pregnant and postpartum rat myometrium. The materials...
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Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing

Kang MJ, Chung YH, Hwang CI, Murata M, Fujimoto T, Mook-Jung , Cha CI, Park WY

  • KMID: 1111405
  • Exp Mol Med.
  • 2006 Apr;38(2):126-133.
Lipid rafts provide a platform for regulating cellular functions and participate in the pathogenesis of several diseases. However, the role of caveolin-1 in this process has not been elucidated definitely...
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Interleukin-1beta Decreases Caveolin-1 Expression in Human Nasal Epithelium

Kim M, Kim BM, Choi YS, Han GS, Yoon SY, Park CS, Shin MK, Jang TY

  • KMID: 2276827
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Jan;51(1):46-50.
BACKGROUND AND OBJECTIVES: Caveolin-1 (Cav-1) is the structural protein that is necessary for the formation of caveolae membrane domains. It is known as an inhibitor of various signaling pathways and...
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p38 Kinase Regulates Nitric Oxide-induced Dedifferentiation and Cyclooxygenase-2 Expression of Articular Chondrocytes

Yu SM, Cheong SW, Cho SR, Kim SJ

BACKGROUND: Caveolin, a family of integral membrane proteins are a principal component of caveolae membranes. In this study, we investigated the effect of p38 kinase on differentiation and on inflammatory...
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Glycosphingolipid Modification: Structural Diversity, Functional and Mechanistic Integration of Diabetes

Yamashita

Glycosphingolipids (GSLs) are present in all mammalian cell plasma membranes and intracellular membrane structures. They are especially concentrated in plasma membrane lipid domains that are specialized for cell signaling. Plasma...
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