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Carbapenems and Monobactam

Kim KH

No abstract available.
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In vitro Antimicrobial Susceptibility of Carbapenems, Including Panipenem, against Clinical Isolates in Korea

Lee DG, Kim M, Kang JH, Chun HS, Choi SM, Wie SH, Kim SI, Choi JH, Yoo JH, Shin WS, Kang MW

  • KMID: 1808165
  • Infect Chemother.
  • 2003 Apr;35(2):91-98.
No abstract available.
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Antimicrobial Resistance and Clones of Acinetobacter Species and Pseudomonas aeruginosa

Lee JY, Ko KS

Antimicrobial resistance in bacteria is problematic in clinical settings and is a growing threat to public health. Multidrug-resistant and pandrug-resistant non-fermenters such as Acinetobacter spp. and Pseudomonas aeruginosa have recently...
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The Infinity War: How to Cope with Carbapenem-resistant Enterobacteriaceae

Yoo JH

Carbapenem-resistant Enterobacteriaceae (CRE) are now spread worldwide. In Korea, the number of CRE isolation is rapidly increasing, and impending endemicity is a concern. To cope well with CRE, thorough infection...
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Emergence and Spread of OXA-48-Like Carbapenemase-Producing Enterobacteriaceae

Song W, Jeong SH, Lee J, Lee SS, Lee K

Since 2001, ten more OXA-48 variants have been identified. Shewanella spp. has been thought to be the original host for OXA-48-like enzymes. These enzymes strongly hydrolyze penicillins and weakly hydrolyze...
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Multidrug-resistant Organisms and Healthcare-associated Infections

Kim MN

Multidrug-resistant organisms (MDROs), including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistnat Staphlyococcus aureus (VRSA), vancomycin-resistant enterococci (VRE), multidrug-resistant Acinetobacter baumannii, and multidrug resistant Pseudomonas aeruginosa have been a big challenge in control...
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Antimicrobial Therapy for Infections Caused by Multidrug-Resistant Gram-Negative Bacteria

Kang CI

The incidence of infections caused by multidrug-resistant (MDR) Gram-negative bacteria has increased over the past decade and extensively drug-resistant (XDR) infections are now on the rise, especially in non-fermenters such...
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Antibiotic Resistance and Novel Antibiotics for the Treatment of Urinary Tract Infections

Wagenlehner F

Surveillance data on antibiotic resistance need to be considered with respect to the origin of isolates, types of surveillance studies, and types of types of registered infections. Antibiotic resistance in...
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Risk Factors for Mortality in Patients with Acinetobacter baumannii Bacteremia

Park SY, Choo JW, Kwon SH, Yu SN, Lee EJ, Kim TH, Choo EJ, Jeon MH

BACKGROUND: Acinetobacter baumannii, an opportunistic nosocomial pathogen that can cause significant morbidity and mortality, has emerged as a worldwide problem. The aim of this study was to evaluate the risk...
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New Antimicrobial Agents for Children

Eun BW

  • KMID: 2278818
  • Korean J Pediatr Infect Dis.
  • 2009 Jun;16(1):6-12.
There are relatively few novel antimicrobial agents despite the dramatic increase in antimicrobial resistance and multiple drug resistance of clinical isolates worldwide. Vancomycin is still the most widely used antibiotic...
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Management of Antibiotic-Resistant Acute Pyelonephritis

Lee HN, Yoon H

Acute pyelonephritis (APN) is a common urinary tract infection that affects a large proportion of women. Although antimicrobial therapy is a successful treatment in most cases, empirically, antibiotic resistance has...
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Characteristics of Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa in Korea

Hong JS, Kim JO, Lee H, Bae IK, Jeong SH, Lee K

BACKGROUND: The aim of this study was to investigate the molecular epidemiological characteristics of metallo-beta-lactamase (MBL)-producing Pseudomonas aeruginosa clinical isolates in Korea. MATERIALS AND METHODS: Three hundred and twenty nine P....
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New antimicrobials on the horizon

Lee MS

  • KMID: 2305799
  • Korean J Med.
  • 2009 Jul;77(1):35-51.
Recently, infections caused by antibiotic-resistant bacteria continue to climb in the community and the hospital around the world. Our current antimicrobial agents are gradually becoming ineffective and a new pipeline...
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Genotypes of Metallo-beta-Lactamases Produced by Imipenem-Resistant Acinetobacter spp. Isolates from Clinical Specimens

Kim JH, Jeong SH, Kim BN, Jeong TJ, Kim TS, Kim JC, Jeon BC

  • KMID: 2248647
  • Korean J Infect Dis.
  • 2002 Dec;34(6):360-366.
BACKGROUND: Carbapenem-resistant Acinetobacter spp. are being isolated with increasing frequency from clinical sources. This study was designed to determine the resistance mechanism to carbapenems of Acinetobacter spp. isolates from patients...
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Epidemiology and treatment of antimicrobialresistant gram-negative bacteria in Korea

Kim YA, Park YS

Antimicrobial resistance is becoming one of the greatest challenges to public health worldwide. Infections by antimicrobial-resistant organisms could result in the failure of treatment, increased medical costs, prolonged hospital stays,...
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Antimicrobial Prophylaxis in Urological Surgery

Yamamoto S, Shigemura , Kiyota H, Arakawa S, Japanese Research Group for UTI

Surgical site infection (SSI) is defined as an infection occurring within one month from surgery or intervention. SSIs are classified into three categories: Clean, clean-contaminated, and contaminated. They are defined...
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Strategies for Interpretive Standards of beta-Lactams Susceptibility Testing and Identification of Extended-Spectrum beta-Lactamases and Carbapenemases in Enterobacteriaceae

Park YJ, Song W

The Clinical and Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) have recently revised the susceptibility interpretive criteria of oxyimino-beta-lactams and carbapenems for Enterobacteriaceae. According...
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Prevalence of Metallo-beta-lactamases in Imipenem-non-susceptible Pseudomonas aeruginosa and Acinetobacter baumannii

Ryoo NH, Ha JS, Jeon DS, Kim JR

BACKGROUND: Metallo-beta-lactamases (MBLs) have been reported in gram negative bacilli and are becoming increasingly important clinically because the enzymes hydrolyse almost all beta-lactams, including carbapenems. Thus, the present study was...
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Characterization of Carbapenemase Genes in Enterobacteriaceae Species Exhibiting Decreased Susceptibility to Carbapenems in a University Hospital in Chongqing, China

Xia Y, Liang Z, Su X, Xiong Y

BACKGROUND: Our study was to investigate the prevalence of carbapenemase genes in strains of Enterobacteriaceae species exhibiting decreased susceptibility to carbapenems in our hospital. METHODS: The carbapenemase producing Enterobacteriaceae species were...
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Evaluation of Diagnostic Performance of RAPIDEC CARBA NP Test for Carbapenemase-Producing Enterobacteriaceae

Song W, Yoo G, Hwang GY, Uh Y

BACKGROUND: Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are resistant to most β-lactam antibiotics except carbapenems. In recent years, infrequently isolated Enterobacteriaceae that produce carbapenemase pose a serious threat in the selection of...
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