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ERRATUM: Prognostic Implications of Extranodal Extension in Relation to Colorectal Cancer Location

Kim CW, Kim J, Park Y, Cho DH, Lee JL, Yoon YS, Park IJ, Lim SB, Yu CS, Kim JC

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The Rise of Particle Beam Therapy: Are We Ready for The Potential Game-Changer?

Chie EK, Ahn YC

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Population Attributable Fraction of Helicobacter pylori Infection–Related Gastric Cancer in Korea: A Meta-Analysis

Park Y, Ki M

Purpose This study aimed to determine the proportion of gastric cancer attributable to Helicobactor pylori in the Korean population. Infection with H. pylori has been recognized as the most significant...
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Technological Advances in Charged-Particle Therapy

Park JM, Kim Ji, Wu HG

Charted-particle therapy (CPT) benefits cancer patients by localizing doses in the tumor volume while minimizing the doses delivered to normal tissue through its unique physical and biological characteristics. The world’s...
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Depression, Rather Than Cancer-Related Fatigue or Insomnia, Decreased the Quality of Life of Cancer Patients

Yeo S, Lee J, Kim K, Kim HJ, Chung S

Purpose Cancer-related fatigue is a common and distressing symptom that occurs during cancer treatment. This study aimed to find factors that are related to cancer-related fatigue, and its effect on...
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Who Will Benefit from Charged-Particle Therapy?

Kim KS, Wu HG

Charged-particle therapy (CPT) such as proton beam therapy (PBT) and carbon-ion radiotherapy (CIRT) exhibit substantial physical and biological advantages compared to conventional photon radiotherapy. As it can reduce the amount...
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Genetic Susceptibility of ACE2 and TMPRSS2 in Six Common Cancers and Possible Impacts on COVID-19

Hoang T, Nguyen TQ, Tran TTA

Purpose Coronavirus disease 2019 (COVID-19) pandemic has spread worldwide rapidly and patients with cancer have been considered as a vulnerable group for this infection. This study aimed to examine the...
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Association among Body Mass Index, Genetic Variants of FTO, and Thyroid Cancer Risk: A Hospital-Based Case-Control Study of the Cancer Screenee Cohort in Korea

Hoang T, Song D, Lee J, Lee EK, Hwangbo Y, Kim J

Purpose Obesity has been determined to be associated with fat mass and obesity-associated (FTO) gene and thyroid cancer risk. However, the effect of combined interactions between obesity and the FTO gene...
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Double Tract Reconstruction Reduces Reflux Esophagitis and Improves Quality of Life after Radical Proximal Gastrectomy for Patients with Upper Gastric or Esophagogastric Adenocarcinoma

Ji X, Jin C, Ji K, Zhang J, Wu X, Jia Z, Bu Z, Ji J

Purpose The aim of the present study was to compare the difference between double tract reconstruction and esophagogastrostomy. Materials and Methods Patients who underwent radical proximal gastrectomy with esophagogastrostomy or double...
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Enhanced Efficacy of Combined Therapy with Checkpoint Kinase 1 Inhibitor and Rucaparib via Regulation of Rad51 Expression in BRCA Wild-Type Epithelial Ovarian Cancer Cells

Cho Hy, Kim YB, Park Wh, No JH

Purpose This study aimed to evaluate anticancer effects of combination treatment with poly(ADP-ribose) polymerase (PARP) and checkpoint kinase 1 (Chk1) inhibitors in BRCA wild-type ovarian cancer. PARP inhibitors can function...
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Synergistic Tumoricidal Effects of Alpha-Lipoic Acid and Radiotherapy on Human Breast Cancer Cells via HMGB1

Choi HS, Kim JH, Jang SJ, Yun JW, Kang KM, Jeong H, Ha IB, Jeong BK

Purpose Radiotherapy (RT) is one of main strategies of cancer treatment. However, some cancer cells are resistant to radiation-induced cell death, including apoptosis. Therefore, alternative approaches targeting different anti-tumor mechanisms...
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Optimal Maintenance Strategy for First-Line Oxaliplatin-Containing Therapy with or without Bevacizumab in Patients with Metastatic Colorectal Cancer: A Meta-Analysis

Moriwaki T, Gosho M, Sugaya A, Yamada T, Yamamoto Y, Hyodo I

Purpose Maintenance therapy after oxaliplatin withdrawal is useful in patients with metastatic colorectal cancer (mCRC). This study aimed to investigate the timing of discontinuation or reintroduction of oxaliplatin and the...
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Identification of a Novel CSNK2A1-PDGFRB Fusion Gene in a Patient with Myeloid Neoplasm with Eosinophilia

Xu X, Lu Q, Wang Z, Cai P, Zeng Z, Zhang L, Wang M, Ma L, Ruan C, Chen S

Platelet-derived growth factor receptor beta (PDGFRB) rearrangements play an important role in the pathogenesis of eosinophilia-associated myeloid/lymphoid neoplasms. Up to now, more than 70 PDGFRB fusions have been identified. Here,...
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Cervical Cancer in Women with Normal Papanicolaou Tests: A Korean Nationwide Cohort Study

Kim M, Kim H, Suh DH, Kim YB

Purpose This study aimed to evaluate the risk of cervical cancer diagnosed within 1 year after the last of multiple consecutive normal Papanicolau (Pap) tests. Materials and Methods The database of...
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Physical and Biological Characteristics of Particle Therapy for Oncologists

Byun HK, Han MC, Yang K, Kim JS, Yoo GS, Koom WS, Kim YB

Particle therapy is a promising and evolving modality of radiotherapy that can be used to treat tumors that are radioresistant to conventional photon beam radiotherapy. It has unique biological and...
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Risk of Coronavirus Disease 2019 Occurrence, Severe Presentation, and Mortality in Patients with Lung Cancer

Yang B, Choi H, Lee SK, Chung SJ, Yeo Y, Shin YM, Park DW, Park TS, Moon JY, Kim TH, Sim YS, Yoon HJ, Sohn JW, Lee H, Kim SH

Purpose This study aimed to analyze whether patients with lung cancer have a higher susceptibility of coronavirus disease 2019 (COVID-19), severe presentation, and higher mortality than those without lung cancer. Materials...
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Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer

Dong SQ, Wang TM, Zhang JB, He YQ, Xue WQ, Wu ZY, Yang DW, Cao LJ, Huang JW, Li XZ, Zhang PF, Zheng XH, Jia WH

Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate...
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Clinical Experience of Male Primary Choriocarcinoma at the Samsung Medical Center

Ji YS, Park SH

Purpose The objective of this study was to describe and analyze the clinicopathological features of primary choriocarcinoma (PCC) observed in male patients treated at the Samsung Medical Center between 1996 and...
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The Establishment of a Fast and Safe Orthotopic Colon Cancer Model Using a Tissue Adhesive Technique

Hu HT, Wang Z, Kim MJ, Jiang LS, Xu SJ, Jung J, Lee E, Park JH, Bakheet N, Yoon SH, Kim KY, Song HY, Chang S

Purpose We aimed to develop a novel method for orthotopic colon cancer model, using tissue adhesive in place of conventional surgical method. Materials and Methods RFP HCT 116 cell line were...
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Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans

Choi CK, Shin MH, Cho SH, Kim HY, Zheng W, Long J, Kweon SS

Purpose Excessive alcohol consumption has been linked to an increased risk of colorectal cancer (CRC). We evaluated the association between alcohol-related genetic variants and CRC risk. Materials and Methods The study...
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