- Fenofibrate regulates obesity and lipid metabolism with sexual dimorphism
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Yoon MC, Jeong SH, Nicol CJ, Lee HH, Han MY, Kim JJ, Seo YJ, Ryu CY, Oh GT
- KMID: 1121103
- Exp Mol Med.
- 2002 Dec;34(6):481-488.
To determine whether the PPARalpha agonist fenofibrate regulates obesity and lipid metabolism with sexual dimorphism, we examined the effects of fenofibrate on body weight, white adipose tissue (WAT) mass,... -
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- Adipogenic and Lipolytic Effects of Ascorbic Acid in Ovariectomized Rats
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Kim B, Choi KM, Yim HS, Park HT, Yim JH, Lee MG
- KMID: 2418853
- Yonsei Med J.
- 2018 Jan;59(1):85-91.
- doi: 10.3349/ymj.2018.59.1.85
PURPOSE: Ascorbic acid has been reported to have an adipogenic effect on 3T3-L1 preadipocytes, while evidence also suggests that ascorbic acid reduces body weight in humans. In this study, we... -
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- Biomedical Issues of Dietary fiber beta-Glucan
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Kim SY, Song HJ, Lee YY, Cho KH, Roh YK
- KMID: 1781892
- J Korean Med Sci.
- 2006 Oct;21(5):781-789.
- doi: 10.3346/jkms.2006.21.5.781
beta-Glucan is a polysaccharide in the form of fiber and the main element of fiber in grains such as barley, oats, yeast and mushrooms. Many studies have examined the efficacy... -
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- Effects of Nitric Oxide Synthase Inhibitor on Hindlimb Muscles in Rats with Neuropathic Pain Induced by Unilateral Peripheral Nerve Injury
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Choe MA, An GJ
- KMID: 1018337
- J Korean Acad Nurs.
- 2011 Aug;41(4):520-527.
- doi: 10.4040/jkan.2011.41.4.520
PURPOSE: The purpose of this study was to examine effects of nitric oxide synthase (NOS) inhibitor on muscle weight and myofibrillar protein content of affected and unaffected hindlimb muscles in... -
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- Protective effects of garlic juice against embryotoxicity of methylmercuric chloride administered to pregnant Fischer 344 rats
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Lee JH, Kang HS, Kang J
- KMID: 711683
- Yonsei Med J.
- 1999 Oct;40(5):483-489.
- doi: 10.3349/ymj.1999.40.5.483
In order to investigate the beneficial effects of 0.5 or 1.0 g/kg Korean garlic juice against the embryotoxicity of 20 mg/kg methylmercury chloride (MMC, CH3HgCl), pregnant Fisher 344 rats were... -
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- Pregabalin as a Neuroprotector after Spinal Cord Injury in Rats: Biochemical Analysis and Effect on Glial Cells
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Ha KY, Carragee E, Cheng I, Kwon SE, Kim YH
- KMID: 2157879
- J Korean Med Sci.
- 2011 Mar;26(3):404-411.
- doi: 10.3346/jkms.2011.26.3.404
As one of trials on neuroprotection after spinal cord injury, we used pregabalin. After spinal cord injury (SCI) in rats using contusion model, we observed the effect of pregabalin compared... -
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- Association of anti-obesity activity of N-acetylcysteine with metallothionein-II down-regulation
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Kim JR, Ryu HH, Chung HJ, Lee JH, Kim SW, Kwun WH, Baek SH, Kim JH
- KMID: 1111409
- Exp Mol Med.
- 2006 Apr;38(2):162-172.
People with upper body or visceral obesity have a much higher risk of morbidity and mortality from obesity-related metabolic disorders than those with lower body obesity. In an attempt to... -
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- Evaluation of the estrogenic effects of dietary perinatal Trifolium pratense
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Yatkin E, Daglioglu
- KMID: 1106553
- J Vet Sci.
- 2011 Jun;12(2):121-126.
- doi: 10.4142/jvs.2011.12.2.121
This study was designed to investigate the potential estrogenic effects of perinatal dietary phytoestrogens on the rat uterus. Pregnant rats were divided to three groups provided the following diets: (1)... -
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- A High Carbohydrate Diet Induces Insulin Resistance Through Decreased Glucose Utilization in Ovariectomized Rats
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Park SM, Park CH, Wha JD, Choi SB
- KMID: 759693
- Korean J Intern Med.
- 2004 Jun;19(2):87-92.
BACKGROUND: Recent research has reported that high sugar diets increase insulin resistance, without abdominal obesity, in male, but not female Wister rats. Whether a high sucrose (SU) diet increased insulin... -
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- Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat
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Baek MW, Seok SH, Lee HY, Kim DJ, Lee BH, Ahn YT, Lim KS, Huh CS, Park JH
- KMID: 1102951
- J Vet Sci.
- 2008 Mar;9(1):31-37.
- doi: 10.4142/jvs.2008.9.1.31
An herbal extract mixture and yogurt added to the herbal extract mixture were tested for their protective and therapeutic effects on ethanol-induced liver injury. The herbal extract mixture, yogurt and... -
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- Pyridoxine induced neuropathy by subcutaneous administration in dogs
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Chung JY, Choi JH, Hwang CY, Youn HY
- KMID: 1106227
- J Vet Sci.
- 2008 Jun;9(2):127-131.
- doi: 10.4142/jvs.2008.9.2.127
To construct a sensory neuropathy model, excess pyridoxine (150 mg/kg s.i.d.) was injected subcutaneously in dogs over a period of 7 days. During the administrations period, the dogs experienced body... -
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- Development of Rat Prostatitis Model by Oral Administration of Isoflavone and Its Characteristics
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Kwon SM, Kim SI, Chun DC, Cho NH, Chung BC, Park BW, Hong SJ
- KMID: 720643
- Yonsei Med J.
- 2001 Aug;42(4):395-404.
- doi: 10.3349/ymj.2001.42.4.395
Inflammation of the prostate can be induced experimentally in rats by the subcutaneous administration of estrogen. However, it is usually achieved at the price of some alteration in the sex... -
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- Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats
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Oh TJ, Shin JY, Kang GH, Park KS, Cho YM
- KMID: 2154249
- Exp Mol Med.
- 2013 Jul;45(7):e30.
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-alpha-dependent manner. We investigated whether a PPARalpha... -
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- Anti-obesity effects of Lysimachia foenum-graecum characterized by decreased adipogenesis and regulated lipid metabolism
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Seo JB, Choe SS, Jeong HW, Park SW, Shin HJ, Choi SM, Park JY, Choi EW, Kim JB, Seen DS, Jeong JY, Lee TG
- KMID: 1104390
- Exp Mol Med.
- 2011 Apr;43(4):205-215.
- doi: 10.3858/emm.2011.43.4.025
Lysimachia foenum-graecum has been used as an oriental medicine with anti-inflammatory effect. The anti-obesity effect of L. foenum-graecum extract (LFE) was first discovered in our screening of natural product extract... -
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- Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver
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Kweon S, Kim Y, Choi H
- KMID: 1093609
- Exp Mol Med.
- 2003 Oct;35(5):371-378.
This study was conducted to examine the effects of dietary grape extracts on preneoplastic foci formation in rat hepatocarcinogenesis, and related hepatic enzymes. Male Sprague-Dawley rats were fed basal diet... -
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- Pirfenidone Suppressed the Development of Glomerulosclerosis in the FGS/Kist mouse
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Park HS, Bao L, Kim YJ, Cho IH, Lee CH, Hyun BH, Margolin S, Park YH
- KMID: 648904
- J Korean Med Sci.
- 2003 Aug;18(4):527-533.
- doi: 10.3346/jkms.2003.18.4.527
Pirfenidone(PFD) is a newly developed anti-fibrotic agent. We evaluated the effect of PFD for the prevention of renal fibrosis using a spontaneous progressive glomerulosclerosis animal model, FGS/Kist mice. Male and... -
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- Effects of Antioxidant on Reduction of Hindlimb Muscle Atrophy Induced by Cisplatin in Rats
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Kim JI, Choe MA
- KMID: 1791866
- J Korean Acad Nurs.
- 2014 Aug;44(4):371-380.
- doi: 10.4040/jkan.2014.44.4.371
PURPOSE: The purpose of this study was to examine the effects of Cu/Zn SOD on reduction of hindlimb muscular atrophy induced by cisplatin in rats. METHODS: Forty-two rats were assigned to... -
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- Glutamine on the Luminal Microbial Environment After Massive Small Bowel Resection
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Choi SH, Lee S, Lee MD
- KMID: 648787
- J Korean Med Sci.
- 2002 Dec;17(6):778-783.
- doi: 10.3346/jkms.2002.17.6.778
To evaluate the oral glutamine (GLN) on the luminal microbes and bacterial translocation (BT) in short bowel, 45 Wistar rats were utilized in three groups; A (control), and B... -
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- Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats
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Kang HG, Jeong SH, Cho MH, Cho JH
- KMID: 1106216
- J Vet Sci.
- 2007 Dec;8(4):361-368.
- doi: 10.4142/jvs.2007.8.4.361
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants present in air and food. Among PAHs, benzo(a)pyrene(BaP), phenanthrene (PH) and pyrene (PY) are considered to be important for their toxicity or... -
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- The Effect of alpha MSH Analogues on Rat Bones
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Lim SK, Li SZ, Rhee Y, Chung SS, Jin YJ, Yook JI
- KMID: 1122009
- Yonsei Med J.
- 2002 Aug;43(4):500-510.
- doi: 10.3349/ymj.2002.43.4.500
Melanocortin is the downstream mediator of leptin signaling and absence of leptin signaling in ob/ob and db/db mice revealed the enhancement of bone formation through the central regulation. While alpha-melanocyte-stimulating... -
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