Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

12 results
Display

Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy

Yu T, Tang B, Sun X

Hypoxia is frequently observed in solid tumors and also one of the major obstacles for effective cancer therapies. Cancer cells take advantage of their ability to adapt hypoxia to initiate...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Relationship between HIF-2α and VEGF with Radiographic Severity in the Primary Osteoarthritic Knee

Jian-lin Z, Hong-song , Hao P, Shuang D, Shen C, Jian-ping , Bo Q, Jin-qing W, Feng L

PURPOSE: The aim of this study was to determine the relationship of hypoxia-inducible factor-2 (HIF-2α) and vascular endothelial growth factor (VEGF) with radiographic severity in primary osteoarthritis (OA) of the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Risk Factors for Metachronous Gastric Neoplasms in Patients Who Underwent Endoscopic Resection of a Gastric Neoplasm

Yoon H, Kim N, Shin CM, Lee HS, Kim BK, Kang GH, Kim JM, Kim JS, Lee DH, Jung HC

BACKGROUND/AIMS: To identify the risk factors for metachronous gastric neoplasms in patients who underwent an endoscopic resection of a gastric neoplasm. METHODS: We prospectively collected clinicopathologic data and measured the methylation...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Crosstalk between FLS and chondrocytes is regulated by HIF-2alpha-mediated cytokines in arthritis

Huh YH, Lee G, Song WH, Koh JT, Ryu JH

Rheumatoid arthritis (RA) and osteoarthritis (OA), two common types of arthritis, affect the joints mainly by targeting the synovium and cartilage. Increasing evidence indicates that a significant network connects synovitis...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of abnormal gene expression in bovine transgenic somatic cell nuclear transfer embryos

Cho J, Kang S, Lee BC

This study was conducted to investigate the expression of three genes related to early embryonic development in bovine transgenic cloned embryos. To accomplish this, development of bovine transgenic somatic cell...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Regulatory Role of Hypoxia Inducible Factor in the Biological Behavior of Nucleus Pulposus Cells

Li H, Liang CZ, Chen QX

Intervertebral disc (IVD) degeneration is implicated as a major cause of low back pain. The alternated phenotypes, reduced cell survival, decreased metabolic activity, loss of matrix production and dystrophic mineralization...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Circadian regulation of low density lipoprotein receptor promoter activity by CLOCK/BMAL1, Hes1 and Hes6

Lee YJ, Han DH, Pak YK, Cho S

  • KMID: 1401756
  • Exp Mol Med.
  • 2012 Nov;44(11):642-652.
Low density lipoprotein receptor (LDLR) plays an important role in the cholesterol homeostasis. We examined the possible circadian regulation of LDLR and mechanism(s) underlying it. In mice, blood glucose and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
ID4 mediates proliferation of astrocytes after excitotoxic damage in the mouse hippocampus

Lee YS, Kang JW, Lee YH, Kim DW

Inhibitor of DNA binding (ID) proteins bind to and inhibit the function of basic helix-loop-helix transcription factors, including those that regulate proliferation and differentiation during development. However, little is known...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic beta cells

Ma WN, Park SY, Han JS

As glucose is known to induce insulin secretion in pancreatic beta cells, this study investigated the role of a phospholipase D (PLD)-related signaling pathway in insulin secretion caused by high...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of a Novel Deletion Region in 3q29 Microdeletion Syndrome by Oligonucleotide Array Comparative Genomic Hybridization

Seo EJ, Jun KR, Yoo HW, Yoo HK, Lee JO

BACKGROUND: The 3q29 microdeletion syndrome is a genomic disorder characterized by mental retardation, developmental delay, microcephaly, and slight facial dysmorphism. In most cases, the microdeletion spans a 1.6-Mb region between...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Novel Translocation t(1;5)(p32;q31) that Was Not Associated with the TAL1 Rearrangement in a Case of T Lymphoblastic Leukemia/Lymphoma

Cho HS, Kim MK, Bae YK

Chromosome 1 band p32 (1p32) aberrations are common in T lymphoblastic leukemia/lymphoma (T-ALL/LBL). Two types of 1p32 aberrations include translocations with different partners and submicroscopic interstitial deletion. Both aberrations are...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer

Song IS, Wang AG, Yoon SY, Kim JM, Kim JH, Lee DS, Kim NS

Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of target genes involved in crucial aspects of cancer development. This study investigated the expression of HIFs and their contribution...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr