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Rapid onset of Stevens-Johnson syndrome and toxic epidermal necrolysis after ingestion of acetaminophen

Kim EJ, Lim H, Park SY, Kim S, Yoon SY, Bae YJ, Kwon HS, Cho YS, Moon HB, Kim TB

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, but life-threatening, severe cutaneous adverse reactions most frequently caused by exposure to drugs. Several reports have associated the use of...
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Drug hypersensitivity in human immunodeficiency virus-infected patient: challenging diagnosis and management

Yunihastuti E, Widhani A, Karjadi TH

Human immunodeficiency virus (HIV)-infected patients present complex immunological alterations. Multiple drugs that usually prescribed for prevention or treatment of opportunistic infections and antiretroviral pose these patients a higher risk of...
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Frequently asked questions in allergy practice

Tan XX, Xie P, Kwek JL, Kwek SY, Yang Z, Soon W, Leong JL, Wang DY

BACKGROUND: Over the last 10-20 years, international guidelines and consensus statements for the management of common allergic diseases (e.g. allergic rhinitis and asthma) have been developed and disseminated worldwide. However,...
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Age of onset as a risk factor of renal involvement in Henoch-Schönlein purpura

Ghrahani R, Ledika MA, Sapartini , Setiabudiawan B

BACKGROUND: Henoch-Schönlein purpura (HSP) is the most common vasculitis in children, characterized by triad of symptoms; palpable purpura without thrombocytopenia, abdominal pain, and arthritis. Renal involvement often occur in children...
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Effects of wheezing in early childhood in the development of allergic rhinitis in later years

Cetinkaya , Atalay OO

BACKGROUND: Studies on the long-term effects of wheezing in infancy have particularly focused on asthma. There isn't adequate information about the effects of wheezing in the development of allergic rhinitis...
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The pH of antiseptic cleansers

Kulthanan , Maneeprasopchoke P, Varothai S, Nuchkull P

BACKGROUND: Daily bathing with antiseptic cleansers are proposed by some physicians as an adjunctive management of atopic dermatitis (AD). As atopic skin is sensitive, selection of cleansing products becomes a...
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Prevalence of asthma and allergic rhinitis among adult population in Ulaanbaatar, Mongolia

Sonomjamts M, Dashdemberel S, Logii N, Nakae K, Chigusa Y, Ohhira S, Ito C, Sagara H, Makino S

BACKGROUND: Mongolia is changing lifestyle, unhealthy habits, increase of air pollution, increasing life expectancy have led to an up rise of chronic respiratory diseases. Over 10 years ago, the prevalence...
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Airway remodelling in asthma: role for mechanical forces

Manuyakorn W

Asthma is a chronic airway inflammatory disease with functional and structural changes, leading to bronchial hyperresponsiveness and airflow obstruction. Airway structural changes or airway remodelling consist of epithelial injury, goblet...
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Epigenetic regulation in allergic diseases and related studies

Kuo CH, Hsieh CC, Lee MS, Chang KT, Kuo HF, Hung CH

Asthma, a chronic inflammatory disorder of the airway, has features of both heritability as well as environmental influences which can be introduced in utero exposures and modified through aging, and...
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Changing the paradigm for cough: does 'cough hypersensitivity' aid our understanding?

Song WJ, Chang YS, Morice AH

Chronic cough is a common reason for patients to seek medication attention. Over the last few decades, we have experienced significant clinical success by applying the paradigm of 'evaluating and...
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Asia Pacific, and beyond

Chang YS, Lee SI

No abstract available.
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