- Apolipoprotein E4: A Risk Factor for Successful Cognitive Aging
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Kwon OD
- KMID: 2442847
- Dement Neurocogn Disord.
- 2016 Sep;15(3):61-67.
- doi: 10.12779/dnd.2016.15.3.61
Apolipoprotein E is a plasma protein that has an important role in transport and metabolism of lipids in serum as well as central nervous system. Among the 3 common alleles,... -
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- Interaction of Apolipoprotein E epsilon4 and Education on Cognitive Decline in Korean Elders
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Kim JM, Shin IS, Kim SW, Yang SJ, Park SW, Shin HY, Yoon JS
- KMID: 1770033
- Korean J Biol Psychiatry.
- 2008 Feb;15(1):29-34.
OBJECTIVES: This study aimed to test potential modifying effects of education on the association between apolipoprotein E epsilon4 (Apo E4) and cognitive decline. METHODS: A community cohort(N=683) aged 65 or over... -
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- Apolipoprotein E4 Genotype and Depressive Symptoms as Risk Factors for Dementia in an Older Korean Population
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Kim JM, Kim SY, Bae KY, Kim SW, Shin IS, Yang SJ, Song YH, Yoon JS
- KMID: 2315879
- Psychiatry Investig.
- 2010 Jun;7(2):135-140.
OBJECTIVE: Growing evidence suggests the separate associations of apolipoprotein E e4 allele (apo E4) and depression with incident dementia. This study investigated the separate and combined effects of apo E4... -
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- Apolipoprotein E Polymorphism and Cholesterol in Stones and Bile of Patients with Cholelithiasis
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Park JS, Seo DW, Yoo KS, Park KM, Lee YJ, Chun SI, Min WK, Lee SK, Kim MH, Lee SG, Min YI
- KMID: 2240364
- Korean J Gastroenterol.
- 2000 Apr;35(4):475-483.
BACKGROUND/AIMS: Apolipoprotein E4 (apo E4) has been reported to be a risk factor for cholesterol gallstone formation. As a cause of cholesterol gallstone formation, increased hepatic uptake of cholesterol absorbed from intestine and... -
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- Analysis of Apolipoprotein E Genotypes in Several Demential diseases
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Park YM, Jeon YM, Kwon GC, Koo SH, Park JW
- KMID: 2225896
- Korean J Clin Pathol.
- 1999 Dec;19(6):642-646.
BACKGROUND: An increased frequency of the epsilon4 allele in Alzheimer's disease has been reported, which suggested a functional role of apolipoprotein E isoforms in pathophysiology of Alzheimer's disease. The aims... -
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- Apolipoprotein E Genetic Polymorphism and Diabetic Microangiopathy in Type 2 Diabetic Patients
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Park JS, Nam JY, Kim CS, Kim DM, Cho MH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC
- KMID: 2008179
- J Korean Diabetes Assoc.
- 2004 Dec;28(6):511-520.
BACKGROUND: The pathophysiological causes for the development and progression of diabetic microangiopathy are not well known, but the apo E genetic polymorphism has been proposed to be involved in the... -
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- Apolipoprotein E Polymorphism in Patients with Gallstones
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Moon JH, Lee YK, Cho YD, Hong SJ, Kim YS, Lee MS, Shim CS
- KMID: 2084904
- Korean J Gastroenterol.
- 1999 Mar;33(3):384-394.
BACKGROUND/AIMS: Cholesterol gallstones which are the most common gallbladder stone found in Western countries are recently increasing in Orient including Korea. The formation of cholesterol stone is frequently associated with... -
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- The Impact of Apolipoprotein E Genetic Polymorphism on Bone Mineral Density in Postmenopausal Women with Rheumatoid Arthritis
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Lee SI, Park JY, Oh SJ, Na YG, Chung CR, Choi YH, Yun HJ, Yoo WH
- KMID: 2202204
- J Korean Rheum Assoc.
- 2006 Dec;13(4):299-305.
OBJECTIVE: To evaluate the relationship between the presence of apolipoprotein E (Apo E) 4 allele and bone mineral density (BMD) and severity of joint destruction in postmenopausal women with rheumatoid... -
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- Blood Lipid Levels, Nutrient Intakes and Health-Related Lifestyles of Industrial Male Workers According to Apolipoprotein E Polymorphisms
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Park YK, Cho SW, Kang JY, Paek YM, Sung SH, Choi TI
- KMID: 2239193
- Korean J Community Nutr.
- 2008 Oct;13(5):713-722.
The purpose of this study was to investigate the association among nutrient intakes and health-related lifestyles with cardiovascular disease risk assessed by blood lipid profile according to Apolipoprotein E genotypes.... -
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- Apolipoprotein E and ACE genetic polymorphism and nephropathy in type 2 diabetic patients
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Park JS, Nam JY, Kim CS, Kim DM, Cho MH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC
- KMID: 2252436
- Korean J Med.
- 2005 May;68(5):511-518.
BACKGROUND: The aim of this study was to investigate the association between apo E and ACE genetic polymorphism and diabetic nephropathy. METHODS: One hundred eighteen patients with type 2 diabetes who... -
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- Apolipoprotein E Genotyping in the Diagnosis and Differential Diagnosis of Alzheimer's Disease
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Bang OY, Kwak YT
- KMID: 2065449
- J Korean Neurol Assoc.
- 2000 Sep;18(5):568-574.
BACKGROUND: There is a growing interest in the use of genetic markers in predicting the various types of dementia such as Alzheimer's disease (AD) and vascular dementia (VD). It is... -
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- Increased Frequency of Apolipoprotein E4 Genotype in Childhood Minimal Change Nephrotic Syndrome (MCNS)
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Kim SD, Bae YM, Cho BS, Cho YW, Kim IS
- KMID: 2144694
- J Korean Soc Pediatr Nephrol.
- 2001 Oct;5(2):87-99.
PURPOSE: We studied to find out apo-E genotype polymorphism in minimal change nephrotic syndrome(MCNS) and IgA nephropathy(IgAN) and to determine the relationship between apo-E genotype and clinical course of MCNS. MATERIALS... -
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- Association of apolipoprotein E polymorphisms with serum lipid profiles in obese adolescent
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Yoon JM, Lim JW, Cheon EJ, Ko KO
- KMID: 1487157
- Korean J Pediatr.
- 2008 Jan;51(1):42-46.
- doi: 10.3345/kjp.2008.51.1.42
PURPOSE: Apolipoprotein E (Apo E) plays a major role in lipoprotein metabolism and lipid transport. Many investigators have described that Apo E polymorphisms is one of the most important genetic... -
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- Influence of Apolipoprotein E Polymorphism into Alteration of Atherosclerotic Cardiovascular Disease in CAPD Patients
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Lee JS, Kang JY, Kim YI, Yang WS, Chae DW, Shin YT, Park JS
- KMID: 2079032
- Korean J Nephrol.
- 1998 Sep;17(5):762-770.
Specific apolipoprotein (apo) E genotype has been suggested as a risk factor for atherosclerosis in the general population. Lipid metabolism is known to be modulated by apo E genotype. In... -
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- Apolipoprotein E Gene and Alpha 1-Antichymotrypsin Gene in Brain of Sporadic Alzheimer's Disease
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Kim SH, Han SY, Choi YS, Lee KS
- KMID: 2137968
- J Korean Neurol Assoc.
- 2002 Nov;20(6):641-651.
BACKGROUND: This study aims to detect any causative genetic alterations and to demonstrate any correlations of these genes in the pathogenesis of mostly late-occurring sporadic type of Alzheimer's disease (AD). METHODS:... -
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- Cerebrospinal Fluid Aspartate Aminotransferase in Alzheimer Disease and Vascular Dementia
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Kim DS, Kwak YT
- KMID: 2188717
- J Korean Geriatr Soc.
- 2001 Mar;5(1):50-55.
BACKGROUND: To evaluate usefulness of cerebrospinal aspartate aminotransferase(AST) as a biologic marker for differentiation of Alzheimer's disease(AD) and Vascular dementia(VD) METHODS: A consecutive series of patients who met either the... -
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- Influences of the Apolipoprotein E Polymorphism on the Development of Coronary Artery Disease and on Serum Lipids in the Korean Males
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Ryu JC, Kim DK, Kim JW, Park WH, Choi JS, Choo JA, Choi YR, Kim MK, Cho BR, Gwon HC, Park SW, Kim JS, Lee SH, Hong KP, Kim DW, Park JE, Lee WR
- KMID: 2093599
- Korean Circ J.
- 1997 Mar;27(3):279-286.
- doi: 10.4070/kcj.1997.27.3.279
BACKGROUND: Apo E lipoprotein is polymorphic and exists in three common isoforms (E2, E3 and E4), which are the gene products of three apo E alleles, e2, e3 and e4.... -
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- Changes of Body Weight and Lipid Profiles According to Apolipoprotein E Polymorphism in Children with Antiepileptics
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Jang SH, Choi EK, Eun SH, Kim SJ
- KMID: 2335565
- J Korean Pediatr Soc.
- 2002 Jan;45(1):88-94.
PURPOSE: Weight changes, especially weight gain, is a side effect of antiepileptics(especially valproate and carbamazepine). This may be sufficiently severe to cause noncompliance or to require the withdrawal of effective... -
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- Association of Apolipoprotein E Genotypes with Late-onset Alzheimer's Disease in Korea
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Lee YS, Na DL, Kim JW
- KMID: 2342525
- J Korean Neurol Assoc.
- 1996 Jun;14(2):538-542.
Apolipoprotein E-epsilon4(APOE4) is recently known as a susceptibility gene or risk factor associated with late-onset Alzheimer's disease (AD). Association between APOE4 and probable AD was determined in Korean population. Twenty... -
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- Interactions of Vascular Risk Factors and Apolipoprotein E4 on Geriatric Depression
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Park HY, Kim JM, Shin IS, Yang SJ, Kim SW, Kim SY, Shin HY, Yoon JS
- KMID: 2249104
- Korean J Biol Psychiatry.
- 2006 May;13(2):103-109.
OBJECTIVE: Associations of vascular risk/disease or apolipoprotein E epsilon4(APOE4) with geriatric depression has been unclear at a population level. This study aimed to evaluate whether there would be interactions of... -
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