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Relationships between [¹⁸F]-THK5351 Retention and Language Functions in Primary Progressive Aphasia

Jeong HJ, Yoon CW, Seo S, Lee SY, Suh MK, Seo HE, Kim WR, Lee H, Heo JH, Lee YB, Park KH, Choi SH, Ido T, Lee KM, Noh Y

BACKGROUND AND PURPOSE: There are three distinct subtypes of primary progressive aphasia (PPA): the nonfluent/agrammatic variant (nfvPPA), the semantic variant (svPPA), and the logopenic variant (lvPPA). We sought to characterize...
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¹⁸F-THK5351 PET Imaging in Nonfluent-Agrammatic Variant Primary Progressive Aphasia

Yoon CW, Jeong HJ, Seo S, Lee SY, Suh MK, Heo JH, Lee YB, Park KH, Okamura N, Lee KM, Noh Y

BACKGROUND AND PURPOSE: To analyze 18F-THK5351 positron emission tomography (PET) scans of patients with clinically diagnosed nonfluent/agrammatic variant primary progressive aphasia (navPPA). METHODS: Thirty-one participants, including those with Alzheimer's disease (AD,...
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Early Onset Alzheimer's Disease Presenting as Logopenic Primary Progressive Aphasia

Oh MJ, Kim S, Park YH, Suh J, Yi S

No abstract available.
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An Autopsy Confirmed Case of Semantic Variant Primary Progressive Aphasia with Frontotemporal Lobar Degeneration-TDP type C

Jung NY, Lee MJ, Lee JH, Shin JH, Lee YM, Shin MJ, Pak K, Hwang C, Ahn JW, Sung S, Choi KU, Huh GY, Kim EJ

A 62-year-old man presented with a one-year history of word finding difficulty, impaired single word comprehension and personality changes including aggression, apathy and eating change. Brain MRIs showed severe atrophy...
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Role of Positron Emission Tomography as a Biologic Marker in the Diagnosis of Primary Progressive Aphasia: Two Case Reports

Jeong YJ, Park KW, Kang DY

Primary progressive aphasia (PPA) is a heterogenous neurodegenerative disorder characterized by declining language and speech ability. Various underlying neuropathologies can induce PPA, and the disorder is divided into three subtypes—progressive...
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Corticobasal Degeneration Presenting as Non-Fluent/Agrammatic Primary Progressive Aphasia: A Case Report

Kim JS, Lee GB, Hong YJ, Park KW

BACKGROUND: Non-fluent agrammatic primary progressive aphasia (naPPA) is characterized by progressive non-fluent speech disorder and might be associated with taupathy such as corticobasal degeneration (CBD) and progressive supranuclear palsy. We...
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Primary Progressive Aphasia and the Left Hemisphere Language Network

Mesulam MM

Primary progressive aphasia (PPA) is a clinical syndrome diagnosed when three core criteria are met. First, there should be a language impairment (i.e., aphasia) that interferes with the usage or...
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Longitudinal Clinical Changes of Non-Fluent/Agrammatic Primary Progressive Aphasia as Tau Spectrum Disorder: A Case Report

Kim JS, Jang JW, Kim SH, Wang MJ, Park YH, Kim S

BACKGROUND: Tauopathies are a group of diseases caused by the accumulation of hyperphosphorylated tau protein in the central nervous system. Previous studies have revealed that there is considerable overlap in...
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A Case of the Fluent Form of Primary Progressive Aphasia Presenting as Conduction Aphasia

Park KW, Kang DY, Kim JW

  • KMID: 2342999
  • J Korean Neurol Assoc.
  • 2002 Jul;20(4):410-413.
Primary progressive aphasia(PPA) can be classified into nonfluent and fluent types. The fluent PPA usually manifests as Wernicke's or transcortical sensory aphasia. We report a 61-year-old right-handed woman who presented...
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Two Cases of Primary Progressive Aphasia

Reu JH, Hwang SR, Jung WY

  • KMID: 2342834
  • J Korean Neurol Assoc.
  • 2000 Jul;18(4):459-464.
Primary progressive aphasia (PPA) is an uncommon neurodegenerative syndrome characterized by a progressive deterioration of language, while nonverbal cognitive and other neurological functions of PPA are relatively preserved for a...
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A case of Primary Progressive Aphasia (PPA)

Lee AY, Oh SK, Kim J, Kim JM

  • KMID: 2342650
  • J Korean Neurol Assoc.
  • 1998 Apr;16(2):219-223.
BACKGROUND AND SIGNIFICANCE: PPA is the clinical syndrome that reveals a marked, progressive loss of language functions over time with relative preservation of non-linguistic cognitive functions. Patients with this syndrome...
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