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Liver Abscess in Advanced Hepatocellular Carcinoma after Sorafenib Treatment

Shin SK, Jung YK, Yoon HH, Kwon OS, Kim YS, Choi DJ, Kim JH

Hepatocellular carcinoma (HCC) is a critical global health issue and the third most common cause of cancer-related deaths worldwide. The majority of patients who present HCC are already at an...
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Immune-Checkpoint Inhibitors in the Era of Precision Medicine: What Radiologists Should Know

Braschi-Amirfarzan M, Tirumani S, Hodi FS, Nishino M

Over the past five years immune-checkpoint inhibitors have dramatically changed the therapeutic landscape of advanced solid and hematologic malignancies. The currently approved immune-checkpoint inhibitors include antibodies to cytotoxic T-lymphocyte antigen-4,...
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A Case of Disseminated Intra-abdominal Gastrointestinal Stromal Tumor Managed with Low Dose Imatinib

Jang BH, Kim BW, Lim KJ, Kim BG, Park SM, Kim JS, Ji JS, Choi H

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. Imatinib mesylate is recommended as adjuvant therapy for GIST after surgical resection. However, drug-related adverse events...
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A Case of Pneumatosis Intestinalis Associated with Sunitinib Treatment for Renal Cell Carcinoma

Choi YA, Sim EH, Lee KE, Ko SY, Seo MJ, Yang YJ, Park JC, Park SY

Sunitinib as a multitarget tyrosine kinase inhibitor is one of the anti-tumor agents, approved by the United States Food and Drug Administration to use treat gastrointestinal stromal tumor and metastatic...
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Pralatrexate in Combination with Bortezomib for Relapsed or Refractory Peripheral T Cell Lymphoma in 5 Elderly Patients

Lee SS, Jung SH, Ahn JS, Kim YK, Cho MS, Jung SY, Lee JJ, Kim HJ, Yang DH

Peripheral T cell lymphoma (PTCL) is a heterogeneous group of aggressive lymphomas with poor prognosis. Elderly (age ≥ 65years) patients generally have impaired bone marrow function, altered drug metabolism, comorbidities,...
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Efficacy and safety of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma as first-line therapy

Oh MJ, Lee HJ, Lee SH

BACKGROUND/AIMS: Hepatic arterial infusion chemotherapy (HAIC) with 5-fluorouracil and cisplatin for intractable advanced hepatocellular carcinoma (HCC) may have survival benefits. We aimed to determine the efficacy and safety of HAIC...
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A Meta-analysis of Chemotherapy related Cognitive Impairment in Patients with Breast Cancer

Park JH, Bae SH

PURPOSE: The purpose of this study was to evaluate the cognitive effects of chemotherapy in patients with breast cancer. METHODS: Using several databases, prospective studies were collected up to August 2011....
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Third-line docetaxel chemotherapy for recurrent and metastatic gastric cancer

Lee JH, Kim SH, Oh SY, Lee S, Lee H, Lee HJ, Kim HJ

BACKGROUND/AIMS: To determine the efficacy and toxicity of docetaxel as a third-line therapy for patients with relapsed gastric cancer who have undergone modified oxaliplatin-fluorouracil (m-FOLFOX)-4 and modified irinotecan-fluorouracil (m-FOLFIRI) regimens. METHODS:...
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A comparative study of sorafenib and metronomic chemotherapy for Barcelona Clinic Liver Cancer-stage C hepatocellular carcinoma with poor liver function

Yang H, Woo HY, Lee SK, Han JW, Jang B, Nam HC, Lee HL, Lee SW, Song DS, Song MJ, Oh JS, Chun HJ, Jang JW, Lozada A, Bae SH, Choi JY, Yoon SK

BACKGROUND/AIMS: Metronomic chemotherapy (MET) is frequently administered in comparatively low doses as a continuous chemotherapeutic agent. The aim of this study was to evaluate the feasibility and overall survival (OS)...
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A study of hepatitis B virus reactivation associated with rituximab therapy in real-world clinical practice: a single-center experience

Oh MJ, Lee HJ

BACKGROUND/AIMS: The widespread use of cytotoxic chemotherapy and immunosuppressants has resulted in reactivation of hepatitis B virus (HBV) recently becoming an issue. Although rituximab (an anti-CD20 monoclonal antibody) has revolutionized...
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Pancreatic Endocrine Tumors: A Report on a Patient Treated with Sorafenib

Jeong HK, Roh SY, Hong SH, Won HS, Jeon EK, Shin OR, Lee SL, Ko YH

A 31-yr-old man with abdominal pain was diagnosed with a pancreatic endocrine tumor and multiple hepatic metastases. Despite optimal treatment with interferon alpha, a somatostatin analog, local therapy with high-intensity...
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Practical Effect of Sorafenib Monotherapy on Advanced Hepatocellular Carcinoma and Portal Vein Tumor Thrombosis

Jeong SW, Jang JY, Shim KY, Lee SH, Kim SG, Cha SW, Kim YS, Cho YD, Kim HS, Kim BS, Kim KH, Kim JH

  • KMID: 1712330
  • Gut Liver.
  • 2013 Nov;7(6):696-703.
BACKGROUND/AIMS: We investigated the effects of sorafenib monotherapy on advanced hepatocellular carcinoma (HCC) and portal vein tumor thrombosis (PVTT) in a clinical setting. METHODS: In total, 143 consecutive patients with unresectable...
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Late-onset Neutropenia Following Rituximab Therapy as a Treatment of Diffuse Large B-cell Lymphoma: A Single Institution Study

Kim M, Lee JK, Hong YJ, Hong SI, Kang HJ, Chang YH

BACKGROUND: Late-onset neutropenia (LON) following rituximab therapy has been reported in recent years. However, its incidence has not been reported in Korea. The aim of this study is to investigate...
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Efficacy and Safety of Cabergoline as First Line Treatment for Invasive Giant Prolactinoma

Cho EH, Lee SA, Chung JY, Koh EH, Cho YH, Kim JH, Kim CJ, Kim MS

Although cabergoline is effective in the treatment of micro- and macro-prolactinoma, little is known about its efficacy in the treatment of invasive giant prolactinoma. We investigated the efficacy and safety...
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The prognostic impact of inflammatory factors in patients with multiple myeloma treated with thalidomide in Korea

Kim C, Lee HS, Min CK, Lee JJ, Kim K, Yoon DH, Eom HS, Lee H, Lee WS, Shin HJ, Lee JH, Park Y, Jo JC, Do YR, Mun YC

BACKGROUND/AIMS: The purpose of this study was to determine the correlations between inflammatory factors-including absolute lymphocyte count, lactate dehydrogenase, beta2-microglobulin, albumin, C-reactive protein, and ferritin-and the prognosis for survival in...
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