- Age-related Changes of Antigen Presenting Cells in Rat Brain
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Jung HS, Yoo KS, Kim HD
- KMID: 1598727
- Korean J Phys Anthropol.
- 2005 Dec;18(4):271-282.
Activation of T cells for an immune response requires the participation of antigen presenting cells that express class II major histocompatibility complex gene products on their surface. As far as... -
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- Antigen Presenting Cells in the Palatine Tonsils and Adenoids
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Sung MW, Chung WH, Oh SH
- KMID: 2274270
- Korean J Otolaryngol-Head Neck Surg.
- 1997 Jan;40(1):34-41.
The functions of the palatine tonsils and adenoids have been investigated for many years, but there are still a lot of debates on their immunological roles. The aim of this... -
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- Distinct features of dendritic cell-based immunotherapy as cancer vaccines
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Lee C, Lee M, Rhee I
- KMID: 2402534
- Clin Exp Vaccine Res.
- 2018 Jan;7(1):16-23.
- doi: 10.7774/cevr.2018.7.1.16
Dendritic cells (DCs) are the most professional antigen presenting cells that play important roles in connection between innate and adaptive immune responses. Numerous studies revealed that the functions of DCs... -
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- Fundamental role of dendritic cells in inducing Th2 responses
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Kim B, Kim TH
- KMID: 2411574
- Korean J Intern Med.
- 2018 May;33(3):483-489.
- doi: 10.3904/kjim.2016.227
A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper... -
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- T cell costimulation by CD28, CTLA-4, and ICOS
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Lee KM
- KMID: 2054219
- Immune Netw.
- 2001 Aug;1(2):95-103.
- doi: 10.4110/in.2001.1.2.95
T cells play a central role in the initiation and regulation of the immune response to foreign antigens. Full activation of T cells requires the engagement of T cell receptor complex... -
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- B Cells Promote Th1- Skewed NKT Cell Response by CD1d-TCR Interaction
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Shin JH, Park SH
- KMID: 1493617
- Immune Netw.
- 2013 Oct;13(5):218-221.
- doi: 10.4110/in.2013.13.5.218
CD1d expressing dendritic cells (DCs) are good glyco-lipid antigen presenting cells for NKT cells. However, resting B cells are very weak stimulators for NKT cells. Although alpha-galactosylceramide (alpha-GalCer) loaded B... -
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- Metformin Suppresses MHC-Restricted Antigen Presentation by Inhibiting Co-Stimulatory Factors and MHC Molecules in APCs
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Shin S, Hyun B, Lee A, Kong H, Han S, Lee CK, Ha NJ, Kim K
- KMID: 2170683
- Biomol Ther.
- 2013 Jan;21(1):35-41.
Metformin is widely used for T2D therapy but its cellular mechanism of action is undefined. Recent studies on the mechanism of metformin in T2D have demonstrated involvement of the immune... -
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- Polarization of T helper Cells Depends on the Presence of Antigen Presentation
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Kim JG, Hahn YS
- KMID: 1550784
- Korean J Immunol.
- 1999 Jun;21(2):137-145.
There are strong evidences suggesting that Thl and Th2 lymphocytes develop from the same Thlymphocyte precursor under the influence of environmental or genetic factors acting at the level of antigen... -
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- Efficient amplification of melanoma-specific CD8+ T cells using artificial antigen presenting complex
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Chang J
- KMID: 1115936
- Exp Mol Med.
- 2006 Dec;38(6):591-598.
In vitro large amplification of tumor-specific cytotoxic T lymphocytes (CTLs) and adoptive transfer of these cells is one of the most promising approaches to treat malignant diseases in which an... -
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- The Role of B Cells in Transplantation Rejection
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Kim TJ
- KMID: 2408661
- J Korean Soc Transplant.
- 2018 Mar;32(1):1-6.
- doi: 10.4285/jkstn.2018.32.1.1
B cells play a role in graft rejection via several mechanisms. Specifically, B cells produce high-affinity antibodies to alloantigens including allogeneic major histocompatibility complex (MHC) with the help of follicular... -
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- The Use of Canine Bone-Marrow Stromal Cell Line, DO64, as Feeder Cells for The Efficient Cloning of Human B Lymphoblastoid Cell Lines ( B-LCLs )
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Kim TG, Han H, Kim YS, Cho HI
- KMID: 1550780
- Korean J Immunol.
- 1999 Jun;21(2):109-113.
Epstein-Barr virus (EBV) is a potent inducer of polyclonal B lymphocyte proliferation and a tool for the establishment of human B lymphoblastoid cell lines (B-LCLs), which have proven useful for... -
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- Vaccine strategies utilizing C-type lectin receptors on dendritic cells in vivo
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Park CG
- KMID: 1730619
- Clin Exp Vaccine Res.
- 2014 Jul;3(2):149-154.
- doi: 10.7774/cevr.2014.3.2.149
Dendritic cells (DCs) are professional antigen-presenting cells capable of initiating and regulating innate and adaptive immunity. The development of effective ways to produce a large number of DCs in laboratories... -
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- Enhancement of Proliferation and Antigen Presentation of Human B Cells in Vitro by K562 Cells Expressing CD40L
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Park JY, Yoon SH, Kim EK, Yun SO, Sohn HJ, Kim TG
- KMID: 2150630
- Immune Netw.
- 2007 Jun;7(2):80-86.
- doi: 10.4110/in.2007.7.2.80
BACKGROUND: CD40-activated B (CD40-B) cells might be an attractive source of autologous antigen-presenting cells (APCs) for immunotherapy due to the convenience to obtain from peripheral blood and expand in vitro.... -
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- Induction of Donor-Specific Tolerance: Is This Achievable?
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Cho EJ, Park JI, An JN, Kim YS
- KMID: 1776577
- Korean J Intern Med.
- 2012 Mar;27(1):114-114.
- doi: 10.3904/kjim.2012.27.1.114
No abstract available. -
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- Emerging Co-signaling Networks in T Cell Immune Regulation
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Jung K, Choi I
- KMID: 1493612
- Immune Netw.
- 2013 Oct;13(5):184-193.
- doi: 10.4110/in.2013.13.5.184
Co-signaling molecules are surface glycoproteins that positively or negatively regulate the T cell response to antigen. Co-signaling ligands and receptors crosstalk between the surfaces of antigen-presenting cells (APCs) and T... -
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- Cordyceps militaris Enhances MHC-restricted Antigen Presentation via the Induced Expression of MHC Molecules and Production of Cytokines
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Shin S, Park Y, Kim S, Oh HE, Ko YW, Han S, Lee S, Lee CK, Cho K, Kim K
- KMID: 2150672
- Immune Netw.
- 2010 Aug;10(4):135-143.
- doi: 10.4110/in.2010.10.4.135
BACKGROUND: Cordyceps militarys water extract (CME) has been reported to exert antitumor and immunomodulatory activities in vivo and in vitro. However, the therapeutic mechanism has not yet been elucidated. In... -
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- Recent progress of elucidating the mechanisms of drug hypersensitivity
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Hashizume
- KMID: 2397483
- Asia Pac Allergy.
- 2012 Jul;2(3):203-209.
- doi: 10.5415/apallergy.2012.2.3.203
Recent technical approaches to investigating drug hypersensitivity have provided a great deal of information to solve the mechanisms that remain poorly understood. First, immunological investigations and in silico analysis have... -
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- TGF-beta-treated antigen presenting cells suppress collagen-induced arthritis through the promotion of Th2 responses
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Jung S, Park YK, Lee H, Shin JH, Lee GR, Park SH
- KMID: 946651
- Exp Mol Med.
- 2010 Mar;42(3):187-194.
- doi: 10.3858/emm.2010.42.3.019
Collagen-induced arthritis (CIA) is mediated by self-reactive CD4+ T cells that produce inflammatory cytokines. TGF-beta2-treated tolerogenic antigen-presenting cells (Tol-APCs) are known to induce tolerance in various autoimmune diseases. In this... -
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- Effect of Lipofectin on Antigen-presenting Function and Anti-tumor Activity of Dendritic Cells
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Noh YW, Lim JS
- KMID: 2150620
- Immune Netw.
- 2006 Jun;6(2):102-111.
- doi: 10.4110/in.2006.6.2.102
BACKGROUND: Dendritic cells (DC) are professional antigen-presenting cells in the immune system and can induce T cell response against virus infections, microbial pathogens, and tumors. Therefore, immunization using DC loaded... -
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- Dendritic Cell Functions in Allergen Recognition and Response
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Han M
- KMID: 2314366
- Pediatr Allergy Respir Dis.
- 2005 Jun;15(2):87-97.
Dendritic cells (DCs) are crucial in the defense against pathogens and allergen. The ability of allergens to cause allergic inflammation is contingent upon the presence of microenvironment that either privileges... -
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