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A case of living-related kidney transplantation in Bartter's syndrome

Kim JY, Kim GA, Song JH, Lee SW, Han JY, Lee JS, Kim MJ

Bartter's syndrome is a renal tubular disorder characterized by hypokalemia, metabolic alkalosis, increased urinary excretion of potassium and prostaglandins, a relative vascular resistance to the pressor effects of exogenous angiotensin...
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Drug-Induced Liver Injury: Pattern Recognition and Future Directions

Haque T, Sasatomi E, Hayashi PH

Drug-induced liver injury (DILI) remains a significant clinical challenge and is the leading cause of acute liver failure in most countries. An aging population that uses more medications, a constant...
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Risk Factors of Drug Interaction between Warfarin and Nonsteroidal Anti-Inflammatory Drugs in Practical Setting

Choi KH, Kim AJ, Son IJ, Kim KH, Kim KB, Ahn H, Lee EB

Nonsteroidal anti-inflammatory drugs (NSAIDs) are known to interact with the oral anticoagulant warfarin and can cause a serious bleeding complication. In this study, we evaluated the risk factors for international...
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Differences in risk for type 1 and type 2 ovarian cancer in a large cancer screening trial

Terada KY, Ahn HJ, Kessel B

OBJECTIVE: To investigate the role of previous gynecologic surgery, hormone use, and use of non-steroidal anti-inflammatory drugs on the risk of type 1 and type 2 ovarian cancer. METHODS: We utilized...
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Safe Re-administration of Tumor Necrosis Factor-alpha (TNFalpha) Inhibitors in Patients with Rheumatoid Arthritis or Ankylosing Spondylitis Who Developed Active Tuberculosis on Previous Anti-TNFalpha Therapy

Suh YS, Kwok SK, Ju JH, Park KS, Park SH, Yoon CH

There is no consensus on whether it is safe to re-administer tumor necrosis factor-alpha (TNFalpha) inhibitors in patients with rheumatoid arthritis (RA) or ankylosing spondylitis (AS) flared after withdrawal of...
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The Prescription Pattern of Acetaminophen and Non-Steroidal Anti-Inflammatory Drugs in Patients with Liver Cirrhosis

Hong YM, Yoon KT, Heo J, Woo HY, Lim W, An DS, Han JH, Cho M

Analgesics, known to be hepatotoxic drugs, are frequently prescribed to patients with liver cirrhosis who are prone to drug-induced liver injury. No guidelines are available regarding the prescription of analgesics...
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Spontaneously Reported Hepatic Adverse Drug Events in Korea: Multicenter Study

Kwon H, Lee SH, Kim SE, Lee JH, Jee YK, Kang HR, Park BJ, Park JW, Hong CS

Hepatic adverse drug reactions (ADRs) to certain drugs may differ within each country, reflecting different patterns of prescription, socioeconomic status, and culture. The purpose of this study was to assess...
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25 Years of Proton Pump Inhibitors: A Comprehensive Review

Strand DS, Kim D, Peura DA

Proton pump inhibitors (PPIs) were clinically introduced more than 25 years ago and have since proven to be invaluable, safe, and effective agents for the management of a variety of...
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Changes in Upper Gastrointestinal Diseases according to Improvement of Helicobacter pylori Prevalence Rate in Korea

Park SH

Helicobacter pylori can cause variety of upper gastrointestinal disorders such as peptic ulcer, mucosa associated lymphoid tissue (MALT)-lymphoma, and gastric cancer. The prevalence of H. pylori infection has significantly decreased...
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Serum Specific IgE to Thyroid Peroxidase Activates Basophils in Aspirin Intolerant Urticaria

Shin YS, Suh DH, Yang EM, Ye YM, Park HS

Thyroid antibodies are frequently observed in urticaria patients, but their roles in urticaria are not clearly elucidated. We investigated the role of serum specific IgE to thyroid peroxidase (TPO) in...
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Analysis of Risk Factors for Colonic Diverticular Bleeding: A Matched Case-Control Study

Sugihara Y, Kudo SE, Miyachi H, Misawa M, Okoshi S, Okada H, Yamamoto K

BACKGROUND/AIMS: Diverticular bleeding can occasionally cause massive bleeding that requires urgent colonoscopy (CS) and treatment. The aim of this study was to identify significant risk factors for colonic diverticular hemorrhage. METHODS:...
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A Rare Case of Free Bowel Perforation Associated with Infliximab Treatment for Stricturing Crohn's Disease

Lim CS, Moon W, Park SJ, Park MI, Kim HH, Kim JB, Choi JM, Chang HK, Lee SH

Crohn's disease is characterized by chronic transmural inflammation of the bowel and is associated with serious complications, such as bowel strictures, abscesses, fistula formation, and perforation. As neither medical nor...
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Characteristics of urinary retention in female inpatients managed with medical treatments

Lee CY, Kim CS, Cho WJ

PURPOSE: We aimed to analyze the characteristics of urinary retention (UR) in female inpatients managed with medical treatments. MATERIALS AND METHODS: We retrospectively analyzed the medical records of female inpatients referred...
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A Case of Acute Pancreatitis Induced by Multiple Drugs in a Patient with Ulcerative Colitis

Son CN, Lee HL, Joo YW, Lee OY, Han DS, Yoon BC, Choi HS, Hahm JS

  • KMID: 1767625
  • Korean J Gastroenterol.
  • 2008 Sep;52(3):192-195.
Acute pancreatitis is a serious disease with fatality rate up to 15%. We recently experienced a case of acute pancreatitis induced by multiple drugs in a patient with ulcerative colitis....
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The Risk of Tuberculosis in Korean Patients with Inflammatory Bowel Disease Receiving Tumor Necrosis Factor-alpha Blockers

Byun JM, Lee CK, Rhee SY, Kim HJ, Kim JW, Shim JJ, Jang JY

The aims of this study were to assess the risk of tuberculosis (TB) and the status of latent tuberculosis infection (LTBI) in Korean patients with inflammatory bowel disease (IBD) receiving...
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A Case of BOOP Developed during Bucillamine Treatment for Rheumatoid

Lee YH, Kim YR, Ji JD, Shim JJ, Kang KH, Lee JH, Kim HK, Song GG

  • KMID: 759533
  • Korean J Intern Med.
  • 2001 Mar;16(1):36-39.
We describe a patient with rheumatoid arthritis(RA) who developed bronchiolitis obliterans organizing pneumonia(BOOP) during the treatment of bucillamine. A 51 year-old man was admitted to the hospital for an abnormal...
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Gastroprotective Effect of Cochinchina momordica Seed Extract in Nonsteroidal Anti-Inflammatory Drug-Induced Acute Gastric Damage in a Rat Model

Lim JH, Kim JH, Kim N, Lee BH, Seo PJ, Kang JM, Jo SY, Park JH, Nam RH, Chang H, Kwon JW, Lee DH

  • KMID: 1774528
  • Gut Liver.
  • 2014 Jan;8(1):49-57.
BACKGROUND/AIMS: The major compounds of Cochinchina momordica seed extract (SK-MS10) include momordica saponins. We report that the gastroprotective effect of SK-MS10 in an ethanol-induced gastric damage rat model is mediated...
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Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Induced by Celecoxib and Anti-tuberculosis Drugs

Lee JH, Park HK, Heo J, Kim TO, Kim GH, Kang DH, Song GA, Cho M, Kim DS, Kim HW, Lee CH

Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome reflects a serious hypersensitivity reaction to drugs, characterized by skin rash, fever, lymph node enlargement, and internal organ involvement. So far,...
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