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Role of Murine Asthma Model in Discovering Asthma Susceptible Genes

Park CS

No abstract available.
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Munchausen Stridor-A Strong False Alarm of Anaphylaxis

Bahna SL, Oldham JL

The diagnosis of anaphylaxis is often based on reported symptoms which may not be accurate and lead to major psychosocial and financial impacts. We describe two adult patients who were...
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A Case of Chronic Cough Caused by Achalasia Misconceived as Gastroesophageal Reflux Disease

Kwon HY, Lim JH, Shin YW, Kim CW

Cough is one of the most common symptoms that causes patients to seek outpatient medical care. If cough persists longer than 8 weeks, common causes of chronic cough, such as...
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Diagnosis and Management of Immediate Hypersensitivity Reactions to Cephalosporins

Kim MH, Lee JM

Cephalosporins can cause a range of hypersensitivity reactions, including IgE-mediated, immediate reactions. Cephalosporin allergy has been reported with use of a specific cephalosporin, as a cross-reaction between different cephalosporins or...
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Food Hypersensitivity in Mexican Adults at 18 to 50 Years of Age: A Questionnaire Survey

Bedolla-Barajas M, Bedolla-Pulido TR, Camacho-Pena AS, Gonzalez-Garcia E, Morales-Romero J

PURPOSE: There is limited epidemiological evidence of food hypersensitivity (FH) in the adult population. We aimed to determine the prevalence of FH in Mexican adults, their clinical features and to...
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The Importance of Allergen Avoidance in High Risk Infants and Sensitized Patients: A Meta-analysis Study

Huiyan W, Yuhe G, Juan W, Junyan Z, Shan W, Xiaojun Z, Ailin T

PURPOSE: At this time, there is uncertainty regarding whether allergen avoidance is the most appropriate strategy for managing or preventing allergies. The purpose of this study was to evaluate the...
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Novel genes in Human Asthma Based on a Mouse Model of Allergic Airway Inflammation and Human Investigations

Temesi G, Virag V, Hadadi E, Ungvari I, Fodor LE, Bikov A, Nagy A, Galffy G, Tamasi L, Horvath I, Kiss A, Hullam G, Gezsi A, Sarkozy P, Antal P, Buzas E, Szalai C

PURPOSE: Based on a previous gene expression study in a mouse model of asthma, we selected 60 candidate genes and investigated their possible roles in human asthma. METHODS: In these candidate...
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The Effects of Environmental Toxins on Allergic Inflammation

Yang SN, Hsieh CC, Kuo HF, Lee MS, Huang MY, Kuo CH, Hung CH

The prevalence of asthma and allergic disease has increased worldwide over the last few decades. Many common environmental factors are associated with this increase. Several theories have been proposed to...
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Reference Ranges and Determinant Factors for Exhaled Nitric Oxide in a Healthy Korean Elderly Population

Jo EJ, Song WJ, Kim TW, Park HW, Chang YS, Kim TB, Kim SH, Hur GY, Lee JH, Yoon HJ, Park HS, Cho NH, Moon HB, Min KU, Cho SH

PURPOSE: Exhaled nitric oxide (NO) is a useful non-invasive biomarker for asthma diagnosis; however, the literature suggests that exhaled NO levels may be affected by demographic factors. The present analysis...
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Oral Lovastatin Attenuates Airway Inflammation and Mucus Secretion in Ovalbumin-Induced Murine Model of Asthma

Liou CJ, Cheng PY, Huang WC, Chan CC, Chen MC, Kuo ML, Shen JJ

PURPOSE: Lovastatin is an effective inhibitor of cholesterol synthesis. A previous study demonstrated that lovastatin can also suppress airway hyperresponsiveness (AHR) in murine model of asthma. We aimed to investigate...
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Long-term Effects of Specific Allergen Immunotherapy Against House Dust Mites in Polysensitized Patients With Allergic Rhinitis

Kim SH, Shin SY, Lee KH, Kim SW, Cho JS

PURPOSE: Allergen-specific immunotherapy is the only currently available treatment to modify the natural history of allergic rhinitis (AR). If patients are polysensitized, it is difficult to identify the allergen causing...
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Development of a Questionnaire for the Assessment of Quality of Life in Korean Children With Allergic Rhinitis

Kim JH, Ahn YM, Kim HJ, Lim DH, Son BK, Kang HS, Song YE, Lee HY

PURPOSE: Korean children have their own unique lifestyle based on their living environment and culture. This study aimed to develop a questionnaire to evaluate the quality of life in Korean...
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Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-kappaB Pathways in Nasal Fibroblasts

Park IH, Um JY, Cho JS, Lee SH, Lee SH, Lee HM

PURPOSE: Based on the close relationship between histamine and interleukin 6 (IL-6), we hypothesized that histamine may regulate the production of cytokines, such as IL-6, during allergic inflammation. Here, we...
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The Serine Protease Inhibitor, 4-(2-aminoethyl) Benzene Sulfonyl Fluoride Hydrochloride, Reduces Allergic Inflammation in a House Dust Mite Allergic Rhinitis Mouse Model

Kim BY, Park HR, Shin JH, Kim SW, Cho JH, Park YJ, Kim SW

PURPOSE: Serine protease inhibitors are involved in immune development, anti-inflammatory mechanisms, and tissue repair. In the present study, the serine protease inhibitor 4-(2-aminoethyl) benzene sulfonyl fluoride hydrochloride (AEBSF) was evaluated...
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Relationship Between Indoor Air Pollutant Levels and Residential Environment in Children With Atopic Dermatitis

Lee JH, Lee HS, Park MR, Lee SW, Kim EH, Cho JB, Kim J, Han Y, Jung K, Cheong HK, Lee SI, Ahn K

PURPOSE: This study was aimed to investigate the relationship between indoor air pollutant levels and residential environment in children with atopic dermatitis (AD) living in Seoul. METHODS: A total of 150...
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