Allergy Asthma Immunol Res.  2014 Nov;6(6):475-477. 10.4168/aair.2014.6.6.475.

Role of Murine Asthma Model in Discovering Asthma Susceptible Genes

Affiliations
  • 1Division of Allergy & Respiratory Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. mdcspark@hanmail.net

Abstract

No abstract available.


MeSH Terms

Asthma*

Reference

1. Burrows B, Martinez FD, Halonen M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N Engl J Med. 1989; 320:271–277.
2. Burrows B, Sears MR, Flannery EM, Herbison GP, Holdaway MD, Silva PA. Relation of the course of bronchial responsiveness from age 9 to age 15 to allergy. Am J Respir Crit Care Med. 1995; 152:1302–1308.
3. Bousquet J, Chanez P, Vignola AM, Lacoste JY, Michel FB. Eosinophil inflammation in asthma. Am J Respir Crit Care Med. 1994; 150:S33–S38.
4. Renz H, Autenrieth IB, Brandtzæg P, Cookson WO, Holgate S, von Mutius E, et al. Gene-environment interaction in chronic disease: a European Science Foundation Forward Look. J Allergy Clin Immunol. 2011; 128:S27–S49.
5. Zhang G, Khoo SK, Mäkelä MJ, Candelaria P, Hayden CM, von Hertzen L, et al. Maternal genetic variants of IL4/IL13 pathway genes on IgE with "Western or Eastern environments/lifestyles". Allergy Asthma Immunol Res. 2014; 6:350–356.
6. Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med. 2012; 18:716–725.
7. Kim SH, Sutherland ER, Gelfand EW. Is there a link between obesity and asthma? Allergy Asthma Immunol Res. 2014; 6:189–195.
8. Lee SH, Park JS, Park CS. The search for genetic variants and epigenetics related to asthma. Allergy Asthma Immunol Res. 2011; 3:236–244.
9. Temesi G, Virág V, Hadadi É, Ungvári I, Fodor LE, Bikov A, et al. Novel genes in human asthma based on a mouse model of allergic airway inflammation and human investigations. Allergy Asthma Immunol Res. 2014; 6:496–503.
10. Tölgyesi G, Molnár V, Semsei AF, Kiszel P, Ungvári I, Pócza P, et al. Gene expression profiling of experimental asthma reveals a possible role of paraoxonase-1 in the disease. Int Immunol. 2009; 21:967–975.
11. Ohkawara Y, Lei XF, Stämpfli MR, Marshall JS, Xing Z, Jordana M. Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation. Am J Respir Cell Mol Biol. 1997; 16:510–520.
12. Karp CL, Grupe A, Schadt E, Ewart SL, Keane-Moore M, Cuomo PJ, et al. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nat Immunol. 2000; 1:221–226.
13. Zimmermann N, King NE, Laporte J, Yang M, Mishra A, Pope SM, et al. Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest. 2003; 111:1863–1874.
14. Wirtenberger M, Tchatchou S, Hemminki K, Schmutzhard J, Sutter C, Schmutzler RK, et al. Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer. Carcinogenesis. 2006; 27:2201–2208.
15. Kressler D, Schreiber SN, Knutti D, Kralli A. The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha. J Biol Chem. 2002; 277:13918–13925.
16. Halapi E, Gudbjartsson DF, Jonsdottir GM, Bjornsdottir US, Thorleifsson G, Helgadottir H, et al. A sequence variant on 17q21 is associated with age at onset and severity of asthma. Eur J Hum Genet. 2010; 18:902–908.
17. Ehre C, Rossi AH, Abdullah LH, De Pestel K, Hill S, Olsen JC, et al. Barrier role of actin filaments in regulated mucin secretion from airway goblet cells. Am J Physiol Cell Physiol. 2005; 288:C46–C56.
18. Davis CW, Dickey BF. Regulated airway goblet cell mucin secretion. Annu Rev Physiol. 2008; 70:487–512.
19. Di Valentin E, Crahay C, Garbacki N, Hennuy B, Guéders M, Noël A, et al. New asthma biomarkers: lessons from murine models of acute and chronic asthma. Am J Physiol Lung Cell Mol Physiol. 2009; 296:L185–L197.
20. Blanchet MR, Gold MJ, McNagny KM. Mouse models to evaluate the function of genes associated with allergic airway disease. Curr Opin Allergy Clin Immunol. 2012; 12:467–474.
21. Maddur MS, Miossec P, Kaveri SV, Bayry J. Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies. Am J Pathol. 2012; 181:8–18.
22. Bhakta NR, Woodruff PG. Human asthma phenotypes: from the clinic, to cytokines, and back again. Immunol Rev. 2011; 242:220–232.
23. Allen IC, Jania CM, Wilson JE, Tekeppe EM, Hua X, Brickey WJ, et al. Analysis of NLRP3 in the development of allergic airway disease in mice. J Immunol. 2012; 188:2884–2893.
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