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Effects of Sub Minimal Inhibitory Concentration of Metronidazole and Penicillin on Morphology of Aggregatibacter actinomycetemcomitans: Scanning Electron Microscopy Observation

Kwon YW, Lee SY

Minimal inhibitory concentration (MIC) is the lowest concentration of antibiotics that inhibits the visible growth of bacteria. It has been reported that sub-MIC of antibiotics may result in morphological alterations,...
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Prosthetic Valve Endocarditis caused by HACEK Organisms: a Case Report and Systematic Review of the Literature

Choi HN, Park KH, Park S, Kim JM, Kang HJ, Park JH, Lee MS

HACEK is a rare cause of prosthetic valve endocarditis (PVE). We describe 42-year-old male patient who presented with Aggregatibacter aphrophilus PVE and cerebral infarct. A. aphrophilus was isolated from his...
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Identification of Non-Aggregatibacter actinomycetemcomitans Bacteria Grown on the Tryptic soy-Serum-Bacitracin-Vancomycin Medium

Jo E, Park SN, Kook JK

The aim of this study was to identify the non-Aggregatibacter actinomycetemcomitans bacteria grown on the tryptic soy-serum-bacitracin-vancomycin (TSBV) medium, an A. actinomycetemcomitans selective medium. A total of 82 unidentified bacterial...
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Induction of osteoclastogenesis-inducing cytokines and invasion by alive Aggregatibacter actinomycetemcomitans in osteoblasts

Choi HK, Lee YS, Kim MY, Kim KD, Cha JH, Yoo YJ

Osteoblasts regulate osteoclastogenesis by production of various cytokines. Aggregatibacter(A) actinomycetemcomitans is one of periodontopathogens which invades gingival tissue. Therefore, clarifying the effect of alive A. actinomycetemcomitans on osteoblasts is important...
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A Case of Pyogenic Spondylitis Due to Aggregatibacter aphrophilus

Kim KH, Kim N, Shin KH, Kim SY, Chang CL, Yi J

Aggregatibacter aphrophilus, a normal component of oral cavity flora, mostly causes infective endocarditis and only rarely causes spondylitis; no spondylitis cases have been previously reported in Korea. We report a...
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Nuclear Factor-kappaB Dependent Induction of TNF-alpha and IL-1beta by the Aggregatibacter actinomycetemcomitans Lipopolysaccharide in RAW 264.7 Cells

Na HS, Jeong SY, Park MH, Kim S, Chung J

  • KMID: 1703487
  • Int J Oral Biol.
  • 2014 Mar;39(1):15-22.
Aggregatibacter actinomycetemcomitans is an important pathogen in the development of localized aggressive periodontitis. Lipopolysaccharide (LPS) is a virulent factor of periodontal pathogens that contributes to alveolar bone loss and connective...
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Ursodeoxycholic Acid Inhibits Inflammatory Cytokine Expression in THP-1 Cells Infected with Aggregatibacter actinomycetemcomitans

Song Y, Kim S, Park MH, Na HS, Chung J

BACKGROUND: Periodontitis is an inflammatory disease characterized by the breakdown of tooth-supporting tissues, leading to tooth loss. Aggregatibacter actinomycetemcomitans are major etiologic bacterium causing aggressive periodontitis. Ursodeoxycholic acid (UDCA), a...
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Effect of Sub-Minimal Inhibitory Concentration Antibiotics on Morphology of Periodontal Pathogens

Kwon YW, Lee SY

  • KMID: 1737505
  • Int J Oral Biol.
  • 2014 Jun;39(2):115-120.
Minimal inhibitory concentration (MIC) is the lowest concentration of antibiotics that inhibits the visible growth of a microorganism. It has been reported that sub-MIC of antibiotics may result in morphological...
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Effect of Various Agents on Oral Bacterial Phagocytosis in THP-1 Cells

Song Y, Lee HA, Na HS, Chung J

Phagocytosis is a fundamental process in which phagocytes capture and ingest foreign particles including pathogenic bacteria. Several oral pathogens have anti-phagocytic strategies, which allow them to escape from and survive...
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Antimicrobial Activity of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Periodontopathogens

Park SN, Kook JK

  • KMID: 1709608
  • Int J Oral Biol.
  • 2013 Dec;38(4):149-154.
In general, oleanolic acid (OA) and ursolic acid (UA) have antimicrobial effect against Gram-positive bacteria but not Gram-negative bacteria whereas sophoraflavanone G has antimicrobial activity against both bacterial types. However,...
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Actinobacillus actinomycetemcomitans Indeces Apoptosis of Jurkat Cell Line Through the Cleavage of Poly (ADP-ribose) Polymerase

Lee SH, Seo SY, Jeong SJ, Yoo SH, Park SM, Jeong MH, Yee ST, Kim JM

  • KMID: 2099299
  • J Korean Soc Microbiol.
  • 1998 Oct;33(5):507-519.
No abstract available.
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The effect of photodynamic therapy on Aggregatibacter actinomycetemcomitans attached to surface-modified titanium

Cho K, Lee SY, Chang BS, Um HS, Lee JK

PURPOSE: The purpose of this study was to evaluate the effect of photodynamic therapy (PDT) using erythrosine and a green light emitting diode (LED) light source on biofilms of Aggregatibacter...
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Antimicrobial Effect of Coptidis rhizome Extract against Mutans Streptococci and Periodontopathogens

Park SN, Lim YK, Kook JK

The purpose of the study was to investigate the antimicrobial activity of the methanol extract of Coptidis rhizome against the type strains of cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus,...
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The effect of Actinobacillus actinomycetemcomitans lipopolysaccharide on rat periodontal tissues

Kim CC, Cui DZ, Kim YJ

No abstract available.
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Antimicrobial Activity of Mulberry Leaf against Mutans Streptococci and Periodontopathogens

Park SN, Lim YK, Cho E, Jo E, Park PS, Kook JK

This study investigated the antimicrobial activity of methanol extract of mulberry leaf against 16 strains of mutans streptococci and four species of periodontopathogens: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and...
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Cloning and protein expression of Actinobacillus actinomycetemcomitans cytolethal distending toxin subunit CdtA

Ko SY, Jeong DK, Ryu SH, Kim HS

No abstract available.
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Antimicrobial Activity of Berberine against Oral Bacteria Related to Endodontic Infections

Lee D, Kim MJ, Park SN, Lim YK, Min JB, Hwang HK, Kook JK

  • KMID: 1709607
  • Int J Oral Biol.
  • 2013 Dec;38(4):141-147.
It has been established that berberine has strong antimicrobial effects. Little is known however regarding the antimicrobial activity of berberine against endodontic pathogenic bacteria or its cytotoxicity in human oral...
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Influence of the Sonic Power Toothbrush on Reduction of Gingival inflammation and on the Amount of Interleukin-6, Prevotella intermedia and Actinobacillus actinomycetemcomitans in Periodontal Pocket

Hong JY, Chae GJ, Jung SW, Um YJ, Choi SH, Kim CK

No abstract available.
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Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts from Artemisia annua L.

Kim WS, Choi WJ, Lee S, Kim WJ, Lee DC, Sohn UD, Shin HS, Kim W

The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin-containing extracts had anti-inflammatory effects. Of...
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Identification of Antimicrobial Peptide Hexamers against Oral Pathogens through Rapid Screening of a Synthetic Combinatorial Peptide Library

Song JS, Cho KJ, Kim J, Kim JH

A positional scanning synthetic peptide combinatorial library (PS-SCL) was screened in order to identify antimicrobial peptides against the cariogenic oral bacteria, Streptococcus mutans. Activity against Streptococcus gordonii and Aggregatibacter actinomycetemcomitans...
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