- A Comparison of the Effects of Intranasal and Sublingual Nifedipine for the Treatment of Hypertension during Laparoscopic Cholecystectomy
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Park JW, Baek CW
- KMID: 2237557
- Korean J Anesthesiol.
- 2004 Jul;47(1):54-58.
- doi: 10.4097/kjae.2004.47.1.54
BACKGROUND: Intranasal drug administration has been suggested to be method for the treatment of various systemic cardiovascular disorders such as systemic hypertension and angina pectoris. Nifedipine is usually administered... -
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- Antihypertensive Effects of Nasal Administration of Nifedipine in Patients Anesthetized with Diethyl - Ether
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Nam KY, Park YC, Shin DH, Baik SW, Kim IS, Chung KS
- KMID: 1933126
- Korean J Anesthesiol.
- 1988 Aug;21(4):555-563.
- doi: 10.4097/kjae.1988.21.4.555
The effect of intranasal nifedipine drops in 20 randomly chosen patients with diethyl-ether induced hypertension by inhalation anesthesia was observed. Patients were placed in two groups: the first group received... -
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- Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency
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Jiao J, Zhang L
- KMID: 2442043
- Allergy Asthma Immunol Res.
- 2019 May;11(3):306-319.
- doi: 10.4168/aair.2019.11.3.306
The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract. Intranasal drugs and additives can... -
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- Intranasally Administered Adjunctive Dexmedetomidine Reduces Perioperative Anesthetic Requirements in General Anesthesia
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Wu X, Hang LH, Wang H, Shao DH, Xu YG, Cui W, Chen Z
- KMID: 2374135
- Yonsei Med J.
- 2016 Jul;57(4):998-1005.
- doi: 10.3349/ymj.2016.57.4.998
PURPOSE: Intranasal dexmedetomidine is an effective sedative for premedication and is regularly used to reduce preoperative tension and anxiety in children. This study aimed to assess the effect of intranasally... -
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- Anxiolytic Action of Taurine via Intranasal Administration in Mice
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Jung JH, Kim SJ
- KMID: 2456219
- Biomol Ther.
- 2019 Sep;27(5):450-456.
- doi: 10.4062/biomolther.2018.218
Taurine has a number of beneficial pharmacological actions in the brain such as anxiolytic and neuroprotective actions. We explored to test whether taurine could be transported to the central nervous... -
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- A Comparison Study of Two Different Methods of Administration: Intranasal versus Intramuscular for Pediatric Procedural Sedation and Analgesia
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An KC, Ahn JH, Lee KJ, Jung YS, Choi SC, Cho YS, Lee JS, Lee CA, Kim GW
- KMID: 2332664
- J Korean Soc Emerg Med.
- 2009 Aug;20(4):422-427.
PURPOSE: To compare the efficacy of ketamine between intranasal (IN) administration and intramuscular (IM) injection for pediatric procedural sedation and analgesia (PPSA). METHODS: A prospective study was conducted during 3 months.... -
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- Gene Knockdown in the Olfactory Bulb, Amygdala, and Hypothalamus by Intranasal siRNA Administration
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Kim ID, Kim SW, Lee JK
- KMID: 1472480
- Korean J Anat.
- 2009 Dec;42(4):285-292.
Intranasal administration provides a method of bypassing the blood brain barrier, which separates the systemic circulating system and central interstitial fluid, and directly delivering drugs to the central nervous system.... -
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- Intranasal administration of dexmedetomidine (DEX) as a premedication for pediatric patients undergoing general anesthesia for dental treatment
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Lee Y, Kim J, Kim S, Kim J
- KMID: 2308762
- J Dent Anesth Pain Med.
- 2016 Mar;16(1):25-29.
- doi: 10.17245/jdapm.2016.16.1.25
BACKGROUND: The most important reason for pre-operative administration of medication is to reduce anxiety. Alleviation of fear and anxiety about surgery enables patients to remain comfortable during treatment. Dexmedetomidine (DEX)... -
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- Pulmonary Edema following Phenylephrine Intranasal Spray Administration during the Induction of General Anesthesia in a Child
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Son JS, Lee SK
- KMID: 1734061
- Yonsei Med J.
- 2005 Apr;46(2):305-308.
- doi: 10.3349/ymj.2005.46.2.305
Topical phenylephrine, an agent used to facilitate nasotracheal intubation and prevent nasal mucosal bleeding, can cause severe hypertension in some patients, secondary to its stimulation of alpha-adrenergic receptors. Moreover, a... -
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- Intranasal Administration of Interleukin-1 Receptor Antagonist in a Transient Focal Cerebral Ischemia Rat Model
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Lee JH, Kam EH, Kim JM, Kim SY, Kim EJ, Cheon SY, Koo BN
- KMID: 2375034
- Biomol Ther.
- 2017 Mar;25(2):149-157.
- doi: 10.4062/biomolther.2016.050
The interleukin-1 receptor antagonist (IL-1RA) is a potential stroke treatment candidate. Intranasal delivery is a novel method thereby a therapeutic protein can be penetrated into the brain parenchyma by bypassing... -
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- Effects of Topical Intranasal Doxycycline Treatment in the Rat Allergic Rhinitis Model
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Avincsal M, Ozbal S, Ikiz AO, Pekcetin C, Guneri EA
- KMID: 2278383
- Clin Exp Otorhinolaryngol.
- 2014 Jun;7(2):106-111.
OBJECTIVES: Allergic rhinitis (AR) is a chronic upper respiratory tract disease that inflames the mucous membranes of the nose and occurs when circulating inflammatory cells including eosinophils and basophils migrate... -
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- Intranasal Administration of Oxytocin Attenuates Stress Responses Following Chronic Complicated Stress in Rats
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Yang Y, Yu H, Babygirija R, Shi B, Sun W, Zheng X, Zheng J
- KMID: 2460490
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):611-622.
- doi: 10.5056/jnm19065
BACKGROUND/AIMS: Gastrointestinal (GI) symptoms may develop when we fail to adapt to various stressors of our daily life. Central oxytocin (OXT) can counteract the biological actions of corticotropin-releasing factor (CRF),... -
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- dNP2-ctCTLA-4 inhibits German cockroach extract-induced allergic airway inflammation and hyper-responsiveness via inhibition of Th2 responses
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Lim S, Sohn JH, Koo JH, Park JW, Choi JM
- KMID: 2389290
- Exp Mol Med.
- 2017 Aug;49(8):e362.
- doi: 10.1038/emm.2017.107
German cockroaches are major household allergens that can trigger allergic airway inflammatory diseases with sensitive T-cell responses. Although the use of immune modulatory biologics, such as antibodies, to mediate allergic... -
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- Baculovirus-based Vaccine Displaying Respiratory Syncytial Virus Glycoprotein Induces Protective Immunity against RSV Infection without Vaccine-Enhanced Disease
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Kim S, Chang J
- KMID: 2014651
- Immune Netw.
- 2012 Feb;12(1):8-17.
- doi: 10.4110/in.2012.12.1.8
BACKGROUND: Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract diseases in infancy and early childhood. Despite its importance as a pathogen, there is no licensed... -
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- Increasing the Efficiency of Parkinson's Disease Treatment Using a poly(lactic-co-glycolic acid) (PLGA) Based L-DOPA Delivery System
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Gambaryan , Kondrasheva IG, Severin ES, Guseva AA, Kamensky A
- KMID: 2165529
- Exp Neurobiol.
- 2014 Sep;23(3):246-252.
- doi: 10.5607/en.2014.23.3.246
To compare the efficacy of L-DOPA administered intranasally in the form of nanoparticles (nano-DOPA) and in standard drug forms using a rat Parkinson's Disease (PD) model. L-DOPA-containing nanoparticles (250+/-50 nm)... -
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- The alternative of oral sedation for pediatric dental care
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Kim J, Kim S, Lee DW, Ryu DS
- KMID: 2310703
- J Dent Anesth Pain Med.
- 2015 Mar;15(1):1-4.
In pediatric dentistry, chloral hydrate is habitually selected for sedation of uncooperative children. Although chloral hydrate has been used for decades, various adverse effects are reported and necessity for new... -
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- Intranasal Administration Model for Evaluating Protection Against Influenza Virus in Mice
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Choi SW, Youn HN, Hong W, Park JK, Yuk SS, Kwon JH, Noh JY, Kang JS, Cho KJ, Ryu JJ, Lee JB, Park SY, Choi IS, Lee SW, Song CS
- KMID: 2168703
- J Bacteriol Virol.
- 2015 Mar;45(1):44-50.
- doi: 10.4167/jbv.2015.45.1.44
Antiviral activity against Influenza virus of 14 Lactobacillus species isolated from food was monitored. Lactobacillus species were isolated from traditional Korean fermented food. Each live Lactobacillus was administered into the... -
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- Effect of intranasal steroids on chronic cough caused by upper airway cough syndrome
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Na GW, Lee DG, Kim JY, Park WI, Lee KB, Lee WJ, Kim JE
- KMID: 1803544
- Allergy Asthma Respir Dis.
- 2014 Nov;2(5):362-369.
- doi: 10.4168/aard.2014.2.5.362
PURPOSE: Although upper airway cough syndrome (UACS) is one of the most common causes of chronic cough, there are few reports on the effects of intranasal steroids (INS) on improvement... -
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- Down regulation induced by intermitent intranasal spraying of gonadotropin releasing hormone(GnRH) in idiopathic male infertility
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Kim YC, Choi HK, Cha KY
- KMID: 1960407
- J Korean Androl Soc.
- 1991 Jun;9(1):37-40.
Gonadotropin Releasing Hormone(GnRH) appears to represent a more physiologic approach to increasing the release of the pituitary gonadotropin endogenously. This therapeutic agent is still being investigated. Among various modes of... -
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- A Novel Recombinant BCG Vaccine Encoding Eimeria tenella Rhomboid and Chicken IL-2 Induces Protective Immunity Against Coccidiosis
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Wang Q, Chen L, Li J, Zheng J, Cai N, Gong P, Li S, Li H, Zhang X
- KMID: 1792178
- Korean J Parasitol.
- 2014 Jun;52(3):251-256.
A novel recombinant Bacille Calmette-Guerin (rBCG) vaccine co-expressed Eimeria tenella rhomboid and cytokine chicken IL-2 (chIL-2) was constructed, and its efficacy against E. tenella challenge was observed. The rhomboid gene... -
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