- Roles of Protein Arginine Methyltransferases in the Control of Glucose Metabolism
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Han HS, Choi D, Choi S, Koo SH
- KMID: 2384238
- Endocrinol Metab.
- 2014 Dec;29(4):435-440.
- doi: 10.3803/EnM.2014.29.4.435
Glucose homeostasis is tightly controlled by the regulation of glucose production in the liver and glucose uptake into peripheral tissues, such as skeletal muscle and adipose tissue. Under prolonged fasting,... -
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- The Histone Acetyltransferase hMOF is Overexpressed in Non-small Cell Lung Carcinoma
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Song JS, Chun SM, Lee JY, Kim DK, Kim YH, Jang SJ
- KMID: 2277503
- Korean J Pathol.
- 2011 Aug;45(4):386-396.
BACKGROUND: One of the histone acetyltransferases (HATs) family of proteins, human MOF (hMOF, MYST1), is involved in histone H4 acetylation, particularly at lysine 16 (H4K16Ac), an epigenetic mark of active... -
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- Modulation of gene expression dynamics by co-transcriptional histone methylations
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Woo H, Ha SD, Lee SB, Buratowski S, Kim T
- KMID: 2382717
- Exp Mol Med.
- 2017 Apr;49(4):e326.
- doi: 10.1038/emm.2017.19
Co-transcriptional methylations of histone H3 at lysines 4 and 36, highly conserved methyl marks from yeast to humans, have profound roles in regulation of histone acetylation. These modifications function to... -
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- Expression of a recombinant branched chain alpha-oxo acid dehydrogenase complex E2 (BCOADC-E2) in insect cells and its immunoreactivity to autoimmune sera
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Lee SM, Ko SH, Park JE, Cha SH
- KMID: 754990
- Exp Mol Med.
- 1998 Jun;30(2):65-71.
Preparation of a pure autoantigen by way of recombinant DNA technology has an important value in an accurate diagnosis or prognosis of an autoimmune disease. BCOADC-E2 subunit, a mitochondrial protein, has been... -
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- Free fatty acid-induced histone acetyltransferase activity accelerates lipid accumulation in HepG2 cells
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Chung S, Hwang JT, Park JH, Choi HK
- KMID: 2453283
- Nutr Res Pract.
- 2019 Jun;13(3):196-204.
- doi: 10.4162/nrp.2019.13.3.196
BACKGROUND/OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disease triggered by epigenetic alterations, including lysine acetylation at histone or non-histone proteins, affecting the stability or transcription of lipogenic... -
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- Identifying the KAT6B Mutation via Diagnostic Exome Sequencing to Diagnose Say-Barber-Biesecker-Young-Simpson Syndrome in Three Generations of a Family
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Kim YR, Park JB, Lee YJ, Hong MJ, Kim HT, Kim HJ
- KMID: 2389469
- Ann Rehabil Med.
- 2017 Jun;41(3):505-510.
- doi: 10.5535/arm.2017.41.3.505
Diagnostic exome sequencing (DES) is a powerful tool to analyze the pathogenic variants leading to development delay (DD) and intellectual disability (ID). Recently, heterozygous de novo mutation of the histone... -
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- Aminoglycoside Susceptibility Profiles of Enterobacter cloacae Isolates Harboring the aac(6')-Ib Gene
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Kim SY, Park YJ, Yu JK, Kim YS
- KMID: 1781692
- Korean J Lab Med.
- 2011 Oct;31(4):279-281.
- doi: 10.3343/kjlm.2011.31.4.279
The aminoglycoside 6'-N-acetyltransferases of type Ib (aac(6')-Ib) gene confers resistance to amikacin, tobramycin, kanamycin, and netilmicin but not gentamicin. However, some isolates harboring this gene show reduced susceptibility to amikacin.... -
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- Dissecting the molecular mechanism of nuclear receptor action: transcription coactivators and corepressors
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Lee JW, Cheong JH, Lee YC, Na SY, lee SK
- KMID: 1109302
- Exp Mol Med.
- 2000 Jun;32(2):53-60.
No abstract available. -
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- Histone Acetylation Level and Histone Acetyltransferase/Deacetylase Activity in Ejaculated Sperm from Normozoospermic Men
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Kim JH, Jee BC, Lee JM, Suh CS, Kim SH
- KMID: 1799499
- Yonsei Med J.
- 2014 Sep;55(5):1333-1340.
- doi: 10.3349/ymj.2014.55.5.1333
PURPOSE: The aim of this work was to evaluate nuclear histone acetylation level and total histone acetyltransferase (HAT) and deacetylase (HDAC) activity in ejaculated sperm and their relevance to conventional... -
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- Expression of HAT1 and HDAC1, 2, 3 in Diffuse Large B-Cell Lymphomas, Peripheral T-Cell Lymphomas, and NK/T-Cell Lymphomas
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Min SK, Koh YH, Park Y, Kim HJ, Seo J, Park HR, Cho SJ, Kim IS
- KMID: 2011982
- Korean J Pathol.
- 2012 Apr;46(2):142-150.
BACKGROUND: It has generally been proven that histone acetylation and deacetylation are involved in the malignant transformation. To date, however, this has rarely been studied in cases of malignant lymphoma. METHODS:... -
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- The First Korean Case of Mucopolysaccharidosis IIIC (Sanfilippo Syndrome Type C) Confirmed by Biochemical and Molecular Investigation
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Huh HJ, Seo JY, Cho SY, Ki CS, Lee SY, Kim JW, Park HD, Jin DK
- KMID: 1781302
- Ann Lab Med.
- 2013 Jan;33(1):75-79.
- doi: 10.3343/alm.2013.33.1.75
Mucopolysaccharidosis (MPS) III has 4 enzymatically distinct forms (A, B, C, and D), and MPS IIIC, also known as Sanfilippo C syndrome, is an autosomal recessive lysosomal storage disease caused... -
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- Characteristics of aac(6')-Ib-cr Gene in Extended-Spectrum beta-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolated from Chungnam Area
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Shin SY, Kwon KC, Park JW, Song JH, Ko YH, Sung JY, Shin HW, Koo SH
- KMID: 1781608
- Korean J Lab Med.
- 2009 Dec;29(6):541-550.
- doi: 10.3343/kjlm.2009.29.6.541
BACKGROUND: Concomitant quinolone resistance in extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is a crucial problem in the clinical management of infections. In foreign countries, the fluoroquinolone acetylating aminoglycoside-(6)-N-acetyltransferase (aac[6']-Ib-cr) gene, a novel... -
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