Korean J Anesthesiol.  2005 Aug;49(2):210-215. 10.4097/kjae.2005.49.2.210.

Analysis of Factors related to Postoperative Nausea and Vomiting after Laparoscopic Hysterectomy

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, Daejeon, Korea. seohwy@cnu.ac.kr

Abstract

BACKGROUND: Despite new anesthetic drugs and antiemetics, the incidence of postoperative nausea and vomiting remains between 20% and 70%. The authors tested the hypothesis that seasonal diet and temperature change and preoperative gastric emptying time affects the incidence of postoperative nausea and vomiting.
METHODS
We conducted a retrospective cohort study of 626 women had undergone laparoscopic hysterectomy. Patients were anesthetized with nitrous oxides and inhalation anesthetics or propofol and injected butorphanol or nalbuphine or patient-controlled analgesia for postoperative pain control. Data were collected from records of recovery room and ward nurse's record and analysed with student t-test or chi-square test and logistic regression. Results are presented as mean +/- SD; P <0.05 was considered significant.
RESULTS
The incidence of PONV was 19.2%. Younger age, intraoperative dehydration, non-anemic preoperative state, usage of nalbuphine increase the incidence of PONV. But the incidence of PONV was not increased by type of anesthetic agent (inhalation or propofol), BMI, duration of operation, preoperative gastric emptyng time.
CONCLUSION
There are controversy in cause of PONV. Further well-controlled, double-blind prospective study may be needed.

Keyword

gynecologic surgery; laparoscopic surgery; postoperative nausea and vomiting

MeSH Terms

Analgesia, Patient-Controlled
Anesthetics
Anesthetics, Inhalation
Antiemetics
Butorphanol
Cohort Studies
Dehydration
Diet
Female
Gastric Emptying
Gynecologic Surgical Procedures
Humans
Hysterectomy*
Incidence
Laparoscopy
Logistic Models
Nalbuphine
Oxides
Pain, Postoperative
Postoperative Nausea and Vomiting*
Propofol
Recovery Room
Retrospective Studies
Seasons
Anesthetics
Anesthetics, Inhalation
Antiemetics
Butorphanol
Nalbuphine
Oxides
Propofol
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