Korean J Intern Med.  1998 Jul;13(2):131-135.

A case of hemolytic uremic syndrome associated with Epstein-Barr virus infection

• Lee MH
• Cho KS
• Kahng KW
• Kang CM

Abstract

The precise etiology of hemolytic uremic syndrome (HUS) is unknown. However, it has been associated with bacterial (Shigella, Salmonella, E. coli, S. pneumoniae), Bartonella, and viral (coxsackie, ECHO, influenza, varicella. Epstein-Barr) infections and with endotoxemia. Recently, we experienced a case of HUS in a 16-year-old boy who was in the acute phase of an Epstein-Barr virus (EBV) infection. He had typical manifestations of HUS and EBV infection. He also transiently presented disseminated intravascular coagulation. His renal dysfunction recovered by supportive care, including hemodialysis, plasmapheresis, antihypertensive medication and aspirin. We present this case with a review of the literature as the second report of HUS associated with EBV infection.

MeSH Terms

Adolescence
Follow-Up Studies
Hemolytic-Uremic Syndrome/virology*
Hemolytic-Uremic Syndrome/therapy
Herpesviridae Infections/diagnosis*
Herpesvirus 4, Human/isolation & purification*
Human
Male
Renal Dialysis
Tumor Virus Infections/diagnosis*