J Korean Med Sci.  2002 Dec;17(6):861-863. 10.3346/jkms.2002.17.6.861.

Globus Pallidus Lesions Associated with High Mountain Climbing

Affiliations
  • 1Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dukna@smc.samsung.co.kr
  • 2Department of Neurology, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Masan, Korea.

Abstract

Acute mountain sickness (AMS) occurs commonly in hikers who are rapidly exposed to high altitude environments. Despite the numerous reports of AMS, few studies have reported pallidal lesions associated with altitude sickness. A previously healthy 49-yr-old Korean patient, after ascent to 4,700 m, suffered symptoms consistent with AMS. After returning home, the patient showed changes in personality characterized by abulia, indifference, and indecisiveness. T2 weighted brain magnetic resonance imaging showed high signal lesions involving bilateral globus pallidus. Our case suggests that globus pallidus injury should be included in the differential diagnosis of patients with personality or cognitive change after recovery from AMS.

Keyword

Anoxia; Globus Pallidus; Mountain Climbing; Altitude Sickness

MeSH Terms

Altitude
Altitude Sickness/*complications
Behavior
Brain/pathology
Brain Damage, Chronic/*etiology/pathology
Environment
Globus Pallidus/*pathology
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Mountaineering
Full Text Links
  • JKMS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error