J Korean Neurol Assoc.  2011 Feb;29(1):40-44.

Cognitive Dysfunction Following High Mountain Climbing

Affiliations
  • 1Department of Neurology, Keimyung University School of Medicine, Daegu, Korea. geschwind@dsmc.or.kr
  • 2Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.

Abstract

Few studies have investigated cognitive impairment associated with globus pallidal lesion after acute mountain sickness (AMS). A 54-year-old mountaineer presented with a slowed response, social withdrawal, and apathy after exposure to high altitude. Neuropsychological evaluation revealed impairment in memory and frontal function. MRI revealed bilateral globus pallidal lesions and SPECT revealed decreased blood flow in the left temporal cortex. Symptoms and imaging findings were still impaired after 3 years. We speculate that globus pallidal lesions can cause cognitive dysfunction in AMS.

Keyword

Acute mountain sickness; Globus pallidus; Cognitive dysfunction

MeSH Terms

Altitude
Altitude Sickness
Apathy
Globus Pallidus
Humans
Memory
Middle Aged
Tomography, Emission-Computed, Single-Photon
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