J Korean Neurol Assoc.  2024 Aug;42(3):266-269. 10.17340/jkna.2024.0011.

Central Nervous System Infection with Hypervirulent Klebsiella pneumoniae

Affiliations
  • 1Department of Neurology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
  • 2Department of Laboratory Medicine, Ulsan Univeristy Hospital, University of Ulsan College of Medicine, Ulsan, Korea
  • 3Department of Internal Medicine, Ulsan Univeristy Hospital, University of Ulsan College of Medicine, Ulsan, Korea

Abstract

Hypervirulent Klebsiella pneumoniae (hvKp) infections are being increasingly reported globally, and cause severe central nervous system (CNS) and multiorgan infections even in immunocompetent individuals. The recent emergence of hvKp antibiotic resistance has generated escalating concern about effective infection control for this potentially neuroinvasive pathogen. Herein, we report two cases of Klebsiella pneumoniae-related CNS infection, including one patient with antimicrobial-resistant hvKp, confirmed by string test that demonstrated a hypermucoviscous phenotype.

Keyword

Drug resistance; microbial; Central nervous system infections
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