Cancer Res Treat.  2024 Jul;56(3):721-742. 10.4143/crt.2023.1043.

Clinical Practice Recommendations for the Use of Next-Generation Sequencing in Patients with Solid Cancer: A Joint Report from KSMO and KSP

• Kim M
• Shim HS
• Kim S
• Lee IH
• Kim J
• Yoon S
• Kim HD
• Park I
• Jeong JH
• Yoo C
• Cheon J
• Kim IH
• Lee J
• Hong SH
• Park S
• Jung HA
• Kim JW
• Kim HJ
• Cha Y
• Lim SM
• Kim HS
• Lee Ck
• Kim JH
• Chun SH
• Yun J
• Park SY
• Lee HS
• Cho YM
• Nam SJ
• Na K
• Yoon SO
• Lee A
• Jang KT
• Yun H
• Lee S
• Kim JH
• Kim WS

• KMID: 2557660
• DOI: http://doi.org/10.4143/crt.2023.1043

Abstract

In recent years, next-generation sequencing (NGS)–based genetic testing has become crucial in cancer care. While its primary objective is to identify actionable genetic alterations to guide treatment decisions, its scope has broadened to encompass aiding in pathological diagnosis and exploring resistance mechanisms. With the ongoing expansion in NGS application and reliance, a compelling necessity arises for expert consensus on its application in solid cancers. To address this demand, the forthcoming recommendations not only provide pragmatic guidance for the clinical use of NGS but also systematically classify actionable genes based on specific cancer types. Additionally, these recommendations will incorporate expert perspectives on crucial biomarkers, ensuring informed decisions regarding circulating tumor DNA panel testing.

Keyword

Next-generation sequencing; Solid cancer; Precision medicine; Korea

Reference

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