Korean J Vet Res.  2023 Dec;63(4):e32. 10.14405/kjvr.20230034.

Testicular granular cell tumor of two rabbits: case reports

Affiliations
  • 1Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
  • 2Chaorum Animal Hospital, Seoul 04360, Korea
  • 3Ray Animal Hospital, Suwon 16312, Korea
  • 4Department of Veterinary Pathology, College of Veterinary Medicine, Jeju National University, Jeju 63243, Korea
  • 5Department of Clinical Laboratory Science, Semyung University, Jecheon 27136, Korea

Abstract

Granular cell tumor was described in the testis of two rabbits. Testis from each rabbit was surgically removed and submitted for histopathological diagnosis. Both testes were about 2.0 cm in diameter, firm, and tan. Microscopically, testicular mass consisted of compact sheets of round to polygonal and occasional spindle-shaped cells. The neoplastic cells contain a large amount of eosinophilic granular material in the cytoplasm. The cytoplasmic eosinophilic granules were positive for periodic acid Schiff stain. Immunohistochemically, the neoplastic cells were immunoreactive to Melan-A and vimentin. Based on these results, the testicular mass was diagnosed as a granular cell tumor.

Keyword

granular cell tumor; neoplasms; rabbits; testis
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