Korean J Otorhinolaryngol-Head Neck Surg.  2014 Feb;57(2):108-111. 10.3342/kjorl-hns.2014.57.2.108.

A Case of Thyroid Granular Cell Tumor

• Cho YH
• Ji YB
• Song CM
• Tae K

• KMID: 1508312
• DOI: http://doi.org/10.3342/kjorl-hns.2014.57.2.108

Abstract

Granular cell tumor is an uncommon neoplasm that can occur everywhere in the human body. Granular cell tumor of the thyroid gland is very rare and only eight cases of thyroid granular cell tumor have been reported. Histopathologically, granular cell tumor consists of large polygonal cells with small dark nuclei and abundant, fine, granular eosinophilic cytoplasm that show positive immunohistochemical staining using S-100 protein. Surgical excision is the treatment of choice for granular cell tumor. Recurrence is rare, but inadequate resection of granular cell tumor may cause local recurrence. We have experienced one case of thyroid granular cell tumor that we report here with a review of literatures.

Keyword

Granular cell tumor; Thyroid

MeSH Terms

Cytoplasm
Eosinophils
Granular Cell Tumor*
Human Body
Recurrence
S100 Proteins
Thyroid Gland*
S100 Proteins