J Korean Neurol Assoc.  2023 Aug;41(3):216-219. 10.17340/jkna.2023.3.7.

Coexistence of Posterior Cortical Atrophy and Parkinson’s Disease

• Ko EB
• Hwang IJ
• Kim JW
• Jung DE
• Lee JS
• Yoo SW
• Kim JS

• KMID: 2544802
• DOI: http://doi.org/10.17340/jkna.2023.3.7

Abstract

We report a rare and unique presentation of a patient with early and levodopa-responsive Parkinson’s disease (PD) who exhibited clinical features similar to posterior cortical atrophy (PCA). The imaging evidence suggested the coexistence of PD and PCA, without the presence of amyloid pathology. Although the present case lacks pathologic evidence, this case represents a distinct manifestation of PD characterized by a combination of parkinsonism and early prominent posterior cognitive deficits, reminiscent of the visual variant of Alzheimer’s disease.

Keyword

Posterior cortical atrophy; Parkinson disease; Alzheimer disease