J Korean Neurol Assoc.
1999 Nov;17(6):886-890.
A Case of Alzheimer's Disease Manifesting as Posterior Cortical Atrophy
- Affiliations
-
- 1Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine.
- 2Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine.
- 3Department of Neurology, College of Medicine, Inha University.
Abstract
- A subgroup of patients with progressive degenerative dementia that begins with higher visual dysfunction has been referred to as posterior cortical atrophy (PCA). A 55-year-old woman presented with progressive visual disturbance for 4 years, which was followed by geographical disorientation, impairment of writing and calculation, and memory distur-bance. Neuropsychological deficits were characterized by Balint syndrome, visuospatial dysfunction, prosopagnosia, Gerstmann syndrome and apraxia. Brain MRI showed mild diffuse atrophy. F18-FDG-PET disclosed bilateral occipi-totemporoparietal hypometabolism, more pronounced on the right. Biopsy from right temporal lobe revealed neu-ropathological findings consistent with Alzheimer's disease.
