Korean J Dermatol.  2023 Jun;61(5):303-307.

A Case of Plaque Psoriasis Associated with Myasthenia Gravis and Graves’ Disease

• Won Y
• Kim Y
• Won SH
• Lee J
• Shin K
• Kim HS
• Ko HC
• Kim MB
• Kim B

Abstract

Psoriasis is a common immune-mediated skin disease. Myasthenia gravis and Graves’ disease are autoimmune diseases caused by autoantibodies against receptors located at the neuromuscular junction and thyroid-stimulating hormone receptor, respectively. A 29-year-old male presented with recurrent multiple erythematous scaly papules and plaques on his legs that had persisted for 3 years. A diagnosis of plaque psoriasis was made based on clinicopathological findings. The patient had a 26-year history of ocular myasthenia gravis, for which he had not been received any specific treatment. He also had a long history of Graves’ disease. To the best of our knowledge, psoriasis with myasthenia gravis and Graves’ disease has not been reported previously in the literature. Herein, we describe our examination of the causes of concurrent psoriasis, myasthenia gravis, and Graves’ disease.

Keyword

Graves disease; Myasthenia gravis; Psoriasis