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Immunoglobulin G4-Related Thyroid Disease: A Single-Center Experience and Literature Review

Jin M, Kim B, Jang A, Jeon MJ, Choi YJ, Lee YM, Song DE, Kim WG

Background: Immunoglobulin G4 (IgG4)-related disease is an entity that can involve the thyroid gland. The spectrum of IgG4-related thyroid disease (IgG4-RTD) includes Hashimoto thyroiditis (HT) and its fibrotic variant, Riedel...
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Usefulness of Real-Time Quantitative Microvascular Ultrasonography for Differentiation of Graves’ Disease from Destructive Thyroiditis in Thyrotoxic Patients

Baek HS, Park JY, Jeong CH, Ha J, Kang MI, Lim DJ

Background: Microvascular ultrasonography (MVUS) is a third-generation Doppler technique that was developed to increase sensitivity compared to conventional Doppler. The purpose of this study was to compare MVUS with conventional...
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Graves’ Disease and the Risk of End-Stage Renal Disease: A Korean Population-Based Study

Cho YY, Kim B, Shin DW, Jang HR, Kim BY, Jung CH, Kim JH, Kim SW, Chung JH, Han K, Kim TH

Background: Hyperthyroidism is associated with an increased glomerular filtration rate (GFR) in the hyperdynamic state, which is reversible after restoring euthyroidism. However, long-term follow-up of renal dysfunction in patients with...
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The Occurrence of a Thyroid Storm in a Patient with Recurrent Refractory Peptic Ulcer: A Case Report

Park K, Jang JY, Lee S

A thyroid storm is a rare complication of hyperthyroidism. Although a thyroid storm rarely presents with symptoms similar to those of an acute abdomen, and in cases where emergency surgery...
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The Use of Intermittent Intra-Operative Neural Monitoring in Reducing the Recurrent Laryngeal Nerve Palsy Rate in High-Risk Thyroidectomy

Cheng KY, Bryant Chan SY

Purpose: To determine if intra-operative neural monitoring (IONM) is effective in lowering the rate of recurrent laryngeal nerve (RLN) injury, when selectively applied in thyroidectomy for certain diagnoses which carry...
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Risk of Diabetes in Patients with Long-Standing Graves’ Disease: A Longitudinal Study

Song E, Koo MJ, Noh E, Hwang SY, Park MJ, Kim JA, Roh E, Choi KM, Baik SH, Cho GJ, Yoo HJ

Background: The detrimental effects of excessive thyroid hormone on glucose metabolism have been widely investigated. However, the risk of diabetes in patients with long-standing hyperthyroidism, especially according to treatment modality,...
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Clinical Characteristics and Prognosis of Coexisting Thyroid Cancer in Patients with Graves’ Disease: A Retrospective Multicenter Study

Yoon JH, Jin M, Kim M, Hong AR, Kim HK, Kim BH, Kim WB, Shong YK, Jeon MJ, Kang HC

Background: The association between Graves’ disease (GD) and co-existing thyroid cancer is still controversial and most of the previously reported data have been based on surgically treated GD patients. This...
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Antithyroid Drug Treatment in Graves’ Disease

Chung JH

Graves’ disease is associated with thyrotropin (TSH) receptor stimulating antibody, for which there is no therapeutic agent. This disease is currently treated through inhibition of thyroid hormone synthesis or destruction...
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Programmed Cell Death-Ligand 1 (PD-L1) gene Single Nucleotide Polymorphism in Graves’ Disease and Hashimoto’s Thyroiditis in Korean Patients

Yoon JH, Shin Mh, Kim HN, Choi W, Park JY, Hong AR, Kim HK, Kang HC

Background: Programmed cell death-ligand 1 (PD-L1) has an important role in regulating immune reactions by binding to programmed death 1 (PD-1) on immune cells, which could prevent the exacerbation of...
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Position and size of the sphenoid door jamb in the lateral orbital wall for the orbital decompression

Shin KJ, Lee SH, Ha TJ, Shin HJ, Koh KS, Song WC, Paik DJ

The aim of this study was to identify the three-dimensional topography of the sphenoid door jamb (SDJ) in the lateral orbital wall and to propose navigational guidelines for safe deep...
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Changes in Thyroid Peroxidase and Thyroglobulin Antibodies Might Be Associated with Graves' Disease Relapse after Antithyroid Drug Therapy

Choi YM, Kwak MK, Hong SM, Hong EG

BACKGROUND: Graves' disease (GD) is an autoimmune thyroid disorder caused by antibodies stimulating the thyrotropin (TSH) receptor. TSH receptor antibody (TRAb) measurement is useful for predicting GD relapse after antithyroid...
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Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer

Hwangbo Y, Park YJ

Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to have high heritability. Family and twin studies have indicated that genetics plays a major role in the development...
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A Case of Graves' Disease Accompanied with Acute Hepatitis A Virus Infection

Hong SE, Choo JW, Lim SK, Lee SJ, Park JW, Kim SE, Kim JH, Park CK

Concurrent presentation of acute hepatitis A virus (HAV) infection and Graves' disease has not been reported in literature worldwide. Although there is no well-established mechanism that explains the induction of...
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Increased Risk of Chronic Spontaneous Urticaria in Patients With Autoimmune Thyroid Diseases: A Nationwide, Population-based Study

Kim YS, Han K, Lee JH, Kim NI, Roh JY, Seo SJ, Song HJ, Lee MG, Choi JH, Park YM

There was no previous population-based study on the comparison of the risk of chronic spontaneous urticaria (CSU) between autoimmune thyroid diseases (AITD) and age- and gender-matched controls. The primary objective...
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Free Thyroxine, Anti-Thyroid Stimulating Hormone Receptor Antibody Titers, and Absence of Goiter Were Associated with Responsiveness to Methimazole in Patients with New Onset Graves' Disease

Choi HS, Yoo WS

BACKGROUND: Anti-thyroid drug therapy is considered a treatment of choice for Graves' disease; however, treatment response varies among individuals. Although several studies have reported risk factors for relapse after initial...
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Encephalopathy Associated with Autoimmune Thyroid Disease Accompanied by Graves' Disease

Park KS, Lee SH, Cho NY, Choi YA, Ko YM, Nam SW, Nam SM

A patient with encephalopathy associated with autoimmune thyroid disease (EAATD), which is one of the most important differential diagnoses of treatable dementia, presents with various neurological symptoms, such as repetitive...
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Cholestyramine Use for Rapid Reversion to Euthyroid States in Patients with Thyrotoxicosis

Ha J, Jo K, Kang B, Kim MH, Lim DJ

Cholestyramine (CS) is an ion exchange resin, which binds to iodothyronines and would lower serum thyroid hormone level. The use of CS added to conventional antithyroid drugs to control thyrotoxicosis...
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Recent Advances in Autoimmune Thyroid Diseases

Yoo WS, Chung HK

Autoimmune thyroid disease (AITD) includes hyperthyroid Graves disease, hypothyroid autoimmune thyroiditis, and subtle subclinical thyroid dysfunctions. AITD is caused by interactions between genetic and environmental predisposing factors and results in...
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Dilated cardiomyopathy with Graves disease in a young child

Choi YJ, Jang JH, Park SH, Oh JH, Koh DK

Graves disease (GD) can lead to complications such as cardiac arrhythmia and heart failure. Although dilated cardiomyopathy (DCMP) has been occasionally reported in adults with GD, it is rare in...
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Predictive factors for early response to methimazole in children and adolescents with Graves disease: a single-institute study between 1993 and 2013

Hwang SM, Kim MS, Lee DY

PURPOSE: We aimed to investigate the predictive factors for early response to methimazole (MMI) in pediatric patients with Graves disease (GD). METHODS: Our study included 44 pediatric patients who were diagnosed...
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