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Evaluating an In-House Cell-Based Assay for Detecting Antibodies Against Muscle-Specific Tyrosine Kinase in Myasthenia Gravis

Kim MJ, Kim SW, Kim M, Choi YC, Kim SM, Shin HY

Background and Purpose Detecting antibodies against muscle-specific tyrosine kinase (MuSK Abs) is essential for diagnosing myasthenia gravis (MG). We applied an in-house cellbased assay (CBA) to detect MuSK Abs. Methods A...
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Clinical Classification and Scales for Myasthenia Gravis

Kim SW, Shin HY

The variable predominance of the affected muscle groups and the fluctuating severity and extent of myasthenia gravis (MG) makes it difficult to assess and classify these patients. With new treatments...
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Initial Repetitive Nerve Stimulation Test Predicts Conversion of Ocular Myasthenia Gravis to Generalized Myasthenia Gravis

Kim KH, Kim SW, Shin HY

Background and Purpose A major concern with ocular myasthenia gravis (MG) is the potential conversion to generalized MG. This study was conducted to determine if the repetitive nerve stimulation (RNS)...
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Tuberculosis Meningoencephalomyelitis in Good's Syndrome: a Case Report

Kwon N, Kim HS

Good's syndrome is a rare disease characterized by thymoma associated with combined B- and T-cell immunodeficiency in adults. Due to the lack of early onset of symptoms, it is difficult...
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Uncommon coexistence of myasthenia gravis and amyotrophic lateral sclerosis

Cho EB, Yang TW, Jeong H, Yoon C, Jung S, Park KJ

Myasthenia gravis (MG) and amyotrophic lateral sclerosis (ALS) are distinct disorders. ALS affects motor neurons that control muscle movement, while MG controls communication between neurons and muscles, which occurs at...
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Examining the Impact of Refractory Myasthenia Gravis on Healthcare Resource Utilization in the United States: Analysis of a Myasthenia Gravis Foundation of America Patient Registry Sample

Xin H, Harris LA, Aban IB, Cutter G

BACKGROUND AND PURPOSE: Patients with refractory myasthenia gravis (MG) experience ongoing disease burden that might be reflected in their healthcare utilization. Here we examine the impact of refractory MG on...
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Long-Term Safety and Efficacy of Tacrolimus in Myasthenia Gravis

Kim YH, Shin HY, Kim SM

PURPOSE: Myasthenia gravis (MG) is a lifelong autoimmune disorder that affects neuromuscular transmission. The long-term treatment plan should include immunotherapy. We investigated the long-term safety and efficacy of tacrolimus for...
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Twenty-one-year follow-up of variable onset MELAS syndrome with heteroplasmic nt3243A>G mtDNA mutation: A case report

Song WJ, Lee YJ, Kang JW, Chang MY, Song KS, Kang DY, Kim SZ

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a maternally inherited mitochondrial disorder of which m.3243A>G is the most commonly associated mutation, resulting in an inability to meet...
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Two Cases of Myasthenia Gravis Showing Fatigibility Presenting with Decreased Gain of Smooth Pursuit

Chae JH, Shin HJ, Shin BS, Seo MW, Oh SY

Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies to the acetylcholine receptors of the neuromuscular junction characterized by weakness and abnormal fatigability of the muscles. Therefore, the diagnosis...
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Acute Exacerbation of Myasthenia Gravis after Amoxicillin Therapy

Lee SS

No abstract available.
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Multiple Eruptive Dermatofibromas in a Patient with Myasthenia Gravis Treated with Systemic Corticosteroid

Park GH, Kim T, Park S, Lee HJ, Jin H, Shim WH, Kim GW, Kim HS, Ko HC, Kim BS, Kim MB, You HS

  • KMID: 2449201
  • Korean J Dermatol.
  • 2019 May;57(4):194-196.
Dermatofibroma is a fibrohistiocytic tumor of the skin that commonly occurs as a solitary lesion on the lower extremities of young women. Multiple eruptive dermatofibromas (MEDFs), defined as the presence...
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Anesthetic considerations for a patient with myasthenia gravis undergoing deep sedation in an outpatient oral surgery setting

Prabhu SS, Khan SA, Doudnikoff AL, Reebye UN

Myasthenia gravis (MG) is a neuromuscular autoimmune disorder which clinically presents as muscular weakness and fatigue due to autoantibody formation against acetylcholine receptors (AChR), leading to their subsequent destruction. Due...
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Result of Multiphasic Personality Inventory among Myasthenia Gravis in Late Adolescence Visiting for Conscription Examination

Seong H, Lee J, Oh J, Seo J, Noh SR, Kim T, Nam B

OBJECTIVES: The purpose of this study was to quantitatively assess the degree of myasthenia gravis (MG) affecting mental health through the results of multiphasic military personality inventory in late adolescence. METHODS:...
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B Cell Immunophenotyping and Transcriptional Profiles of Memory B Cells in Patients with Myasthenia Gravis

Min YG, Park C, Kwon YN, Shin JY, Sung JJ, Hong YH

Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorders mediated by various autoantibodies. Although most patients with MG require chronic immunosuppressive treatment to control disease activity, appropriate surveillance biomarkers that...
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Efficacy of Gaze Photographs in Diagnosing Ocular Myasthenia Gravis

Ahn J, Park KS, Kim JS, Hwang JM

BACKGROUND AND PURPOSE: The various tests that are routinely used to diagnose generalized myasthenia gravis, such as the edrophonium test, serum anti-acetylcholine-receptor antibodies (AChR-Ab), and repetitive nerve stimulation (RNS) tests,...
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Myasthenia Gravis with Thymoma Recurrence 20 Years after Thymectomy: What Is the Optimal Follow-up Duration?

Park JA, Kwon DH, Bae CH, Seok JI

Thymoma occurs in about 20% of patients with myasthenia gravis (MG), but the recurrence of thymoma has rarely been reported. A 68-year-old man presented with ptosis and weakness of the...
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Dysphagia as the Only Manifestation of Myasthenia Gravis: A Case Report

Yoon JR, Lee JS, Kim YH

Dysphagia is a common manifestation of myasthenia gravis (MG), but it has been rarely reported as the only symptom. We report a 46-year-old man who complained of dysphagia without any...
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Repetitive Nerve Stimulation in MuSK-Antibody-Positive Myasthenia Gravis

Kim SW, Sunwoo MK, Kim SM, Shin HY, Sunwoo IN

BACKGROUND AND PURPOSE: Responses to repetitive nerve stimulation (RNS) in patients with muscle-specific tyrosine kinase (MuSK) antibody (Ab)-positive myasthenia gravis (MG) vary depending on the muscles tested. We analyzed the...
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Subgroup Classification and Therapeutic Guidance for Myasthenia Gravis

Lee YJ

Myasthenia gravis (MG) is a chronic autoimmune disease of neuromuscular blockade, characterized by muscle weakness and fatigue, and is associated with the production of autoantibodies against the skeletal muscle acetylcholine...
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Remission after Rituximab Therapy in Refractory Myasthenia Gravis

Park JM, Lee HC, Park JS

Myasthenia gravis (MG) is estimated to be refractory in approximately 10% of patients with generalized MG. A 35-year-old man was diagnosed as generalized MG with thymoma. Despite aggressive immunotherapies, his...
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