J Dent Anesth Pain Med.  2023 Jun;23(3):123-133. 10.17245/jdapm.2023.23.3.123.

Ketamine-propofol (ketofol) in procedural sedation: a narrative review

Affiliations
  • 1Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University, Yangsan, Republic of Korea

Abstract

Sedation methods for dental treatment are increasingly explored. Recently, ketofol, which is a combination of ketamine and propofol, has been increasingly used because the advantages and disadvantages of propofol and ketamine complement each other and increase their effectiveness. In this review, we discuss the pharmacology of ketamine and propofol, use of ketofol in various clinical situations, and differences in efficacy between ketofol and other sedatives.

Keyword

Dentistry; Ketamine; Ketofol; Procedural Sedation; Propofol
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