J Pathol Transl Med.  2022 Nov;56(6):383-384. 10.4132/jptm.2022.08.16.

What’s new in kidney tumor pathology 2022: WHO 5th edition updates

• Tretiakova M

• KMID: 2535858
• DOI: http://doi.org/10.4132/jptm.2022.08.16

Abstract

The 5th edition WHO Classification of Urinary and Male Genital Tumours (2022) introduces significant changes relevant to daily practice, especially in the completely restructured renal cell tumor chapters. Herein we highlight the most important diagnostic updates of known kidney tumor types, new and molecularly defined entities and emerging/provisional entities.

Figure

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  Fig. 1. TFEB-amplified RCC.

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  Fig. 2. ALK-rearranged RCC.

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  Fig. 3. Eosinophilic solid and cystic RCC.

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  Fig. 4. Papillary renal neoplasm with reverse polarity.

Reference

References

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2. Trpkov K, Williamson SR, Gill AJ, et al. Novel, emerging and provisional renal entities: The Genitourinary Pathology Society (GUPS) update on renal neoplasia. Mod Pathol. 2021; 34:1167–84.