J Pathol Transl Med.  2022 Nov;56(6):385-386. 10.4132/jptm.2022.10.18.

What’s new in soft tissue and bone pathology 2022–updates from the WHO classification 5th edition

• Kao EY
• Mantilla JG

• KMID: 2535859
• DOI: http://doi.org/10.4132/jptm.2022.10.18

Abstract

The 2020 release of the WHO Classification of Soft Tissue and Bone Tumors, 5th edition, contains several changes driven by new knowledge in the field. These include reclassification of some entities, refinement of risk classification systems, and the inclusion of novel disease processes, many of which are driven by recurrent gene fusions. The most notable changes are described here.

Figure

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  Fig. 1. Angiofibroma of soft tissue.

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  Fig. 2. Superficial CD34-positive fibroblastic tumor.

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  Fig. 3. Round cell sarcoma with EWSR1::non-ETS fusions.

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  Fig. 4. CIC-rearranged sarcoma.

Reference

References

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