Korean J Med.  2021 Feb;96(1):48-52. 10.3904/kjm.2021.96.1.48.

Immunoglobulin G4-Related Kidney Disease with Membranous Proliferative Glomerulonephritis Presenting with a Renal Pelvic Mass

Affiliations
  • 1Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea
  • 2Departement of Pathology, Dankook University College of Medicine, Cheonan, Korea
  • 3Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea

Abstract

Immunoglobulin G4 (IgG4)-related kidney disease is a chronic immune-mediated fibro-inflammatory disorder characterized by multiple organ infiltration with IgG4-positive plasma cells, storiform fibrosis, and obliterative phlebitis or tumefactive lesions. Previous studies have explored IgG4-related kidney disease, increasing our understanding of its clinical manifestations, and pathological and radiologic findings. However, IgG4-related kidney disease can be misdiagnosed since it mimics malignancies. We report a case of a 77-year-old Korean man diagnosed with IgG4-related kidney disease with membranous proliferative glomerulonephritis, presenting with a renal pelvic mass suspected of being malignant.

Keyword

Immunoglobulin G4-related disease; Glomerulonephritis, membranoproliferative; Acute kidney injury; 면역글로불린 G4 연관 신장 질환; 막증식성 사구체 신염, 급성 신손상
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