Korean J Med.  2014 Dec;87(6):710-715. 10.3904/kjm.2014.87.6.710.

A Case of IgG4-Related Pancreas and Kidney Disease Mimicking a Renal Pelvic Malignancy

• Kim WJ
• Noh MH
• Ryu CH
• Han SH
• Nam HS
• Han JE
• Hong SH

• KMID: 2269367
• DOI: http://doi.org/10.3904/kjm.2014.87.6.710

Abstract

IgG4-related sclerosing disease is a disease entity that has recently attracted attention, manifesting as a multiorgan disease characterized by high serum IgG4 levels, extensive IgG4-positive plasma cells and lymphocyte infiltration of the affected organs, with the pancreas (autoimmune pancreatitis) and kidney as representative targets. In cases of renal involvement, parenchymal lesions are predominant, such as renal cortical lesions or diffuse renal enlargement. However, mass-like lesions involving the renal pelvis are very rare, and mass forming or pelvic involvement types should be distinguished from lymphomas, metastatic cancers and other genitourinary malignancies to avoid unnecessary surgery. Herein, we report a case of IgG4-related sclerosing disease involving the kidney as an unusual involvement pattern presenting as a mass-like lesion with pelvic and perirenal involvement.

Keyword

IgG4-related kidney disease; Autoimmune pancreatitis; Renal pelvic mass

MeSH Terms

Immunoglobulin G
Kidney
Kidney Diseases*
Kidney Pelvis
Lymphocytes
Lymphoma
Pancreas*
Plasma Cells
Unnecessary Procedures
Immunoglobulin G