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Identification of Biomarkers for the Diagnosis of Sepsis-Associated Acute Kidney Injury and Prediction of Renal Recovery in the Intensive Care Unit

Kwak SH, Ahn S, Shin MH, Leem AY, Lee SH, Chung K, Kim YS, Lee SG, Park MS

Purpose: Acute kidney injury (AKI) following sepsis is associated with higher mortality; however, reliable biomarkers for AKI development and recovery remain to be elucidated. Materials and Methods: Patients with sepsis admitted...
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Selection of appropriate reference creatinine estimate for acute kidney injury diagnosis in patients with severe trauma

Lee K, Ryu D, Kim H, Park S, Lee S, Park C, Kim G, Kim S, Lee N

Background: In patients with severe trauma, the diagnosis of acute kidney injury (AKI) is important because it is a predictive factor for poor prognosis and can affect patient care. The...
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Impact of intradialytic hypotension on mortality following the transition from continuous renal replacement therapy to intermittent hemodialysis

Kim SG, Yun D, Lee J, Kim YC, Kim DK, Oh KH, Joo KW, Kim YS, Han SS

Background: The transition of dialysis modalities from continuous renal replacement therapy (CRRT) to intermittent hemodialysis (iHD) is frequently conducted during the recovery phase of critically ill patients with acute kidney...
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Melatonin Attenuates Mitochondrial Damage in Aristolochic AcidInduced Acute Kidney Injury

Sun J, Pan J, Liu Q, Cheng J, Tang Q, Ji Y, Cheng K, wang R, Liu L, Wang D, Wu N, Zheng X, Li J, Zhang X, Zhu Z, Ding Y, Zheng F, Li J, Zhang Y, Yuan Y

Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and...
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Effects of Albizia julibrissin Durazz through Suppression of Mitochondrial Fission and Apoptosis in Cisplatin-induced Acute Kidney Injury

Lee HJ, Kim KH, Kim YJ, Cho SP, Hong GL, Jung JY

Albizia julibrissin Durazz. (AJ; family Minosaceae) is widely distributed worldwide, and its stem bark has been used as a traditional herbal medicine. Acute kidney injury (AKI) is a clinical syndrome...
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Association of chloride-rich fluids and medication diluents on the incidence of hyperchloremia and clinical consequences in aneurysmal subarachnoid hemorrhage

Barlow B, Thompson Bastin ML, Shadler A, Cook AM

Background: Chloride-rich fluid administration is frequently employed in the management of aneurysmal subarachnoid hemorrhage (aSAH). However, the incidence and consequences of hyperchloremia in aSAH remain poorly defined. This study aimed...
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The Impact of Surgical versus Transcatheter Aortic Valve Replacement on Postprocedural Acute Kidney Injury in Patients with Chronic Kidney Disease

Kim EC, Kim SH, Lee Y, Sohn SH, Choi JW, Kang J, Han JK, Kim KH, Kim HS, Hwang HY

Background: This study aimed to evaluate the impact of the treatment modality on post-procedural acute kidney injury (AKI) and other clinical outcomes in patients with advanced chronic kidney disease who...
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Hospital mortality and prognostic factors in critically ill patients with acute kidney injury and cancer undergoing continuous renal replacement therapy

Kim DW, Jang GS, Jung KS, Jung HJ, Kim HJ, Rhee H, Seong EY, Song SH

Background: Whether continuous renal replacement therapy (CRRT) should be applied to critically ill patients with both acute kidney injury (AKI) and cancer remains controversial because of poor expected outcomes. The...
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Comparison of Outcomes of Mild and Severe Community- and Hospital-Acquired Acute Kidney Injury

Medina KRP, Jeong JC, Ryu JW, Kang E, Chin HJ, Na KY, Chae DW, Kim S

Purpose: Acute kidney injury (AKI) has shown an increasingly common occurrence among hospitalized patients worldwide. We determined the incidence and compared the short- and long-term outcomes of all stages of...
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Update of Drug-induced Kidney Injury

Lee H

Drug-induced kidney injury is one of the common causes of community- or hospital-acquired kidney injury as well as the adverse effects of drugs. Drugsā€™ innate kidney toxicity, patients having multiple...
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Hydrogen sulfide protects from acute kidney injury via attenuating inflammation activated by necroptosis in dogs

Wang S, Liu X, Liu Y

Background: The treatment of acute kidney injury (AKI), a common disease in dogs, is limited. Therefore, an effective method to prevent AKI in veterinary clinics is particularly crucial. Objectives: Hydrogen sulfide...
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Perioperative anemia predicts kidney injury after partial nephrectomy

Li Q, Huang Y, Zhang L, Duan L, Qian S

Purpose: Partial nephrectomy (PN) induced kidney injury is still a challenging clinical matter that has not been completely conquered. This study aimed to explore the influences of perioperative anemia on...
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Clinical efficacy of blood purification using a polymethylmethacrylate hemofilter for the treatment of severe acute pancreatitis

Kinjoh K, Nagamura R, Sakuda Y, Yamauchi S, Takushi H, Iraha T, Idomari K

Background: Severe acute pancreatitis (SAP) is a systemic inflammatory disease, and it can often complicate into acute kidney injury (AKI) and acute lung injury/acute respiratory distress syndrome (ALI/ARDS). This study...
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Strategies for Renal Protection in Cardiovascular Interventions

Ali ZA, Escaned J, Dudek D, Radhakrishnan J, Galougahi KK

Coronary artery disease is highly prevalent in chronic kidney disease (CKD) and is a risk factor for contrast-associated acute kidney injury (CA-AKI), a complication of cardiovascular procedures that require contrast...
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Role of T cells in ischemic acute kidney injury and repair

Lee K, Jang HR

Ischemic acute kidney injury (AKI) is a common medical problem with significant mortality and morbidity, affecting a large number of patients globally. Ischemic AKI is associated with intrarenal inflammation as...
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Recalibration and validation of the Charlson Comorbidity Index in acute kidney injury patients underwent continuous renal replacement therapy

Lee J, Jung J, Lee J, Park JT, Jung CY, Kim YC, Kim DK, Lee JP, Shin SJ, Park JY

Background: Comorbid conditions impact the survival of patients with severe acute kidney injury (AKI) who require continuous renal replacement therapy (CRRT). The weights assigned to comorbidities in predicting survival vary...
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Estimating baseline creatinine values to define acute kidney injury in critically ill pediatric patients

Lee YJ, Park YS, Park SJ, Jhang WK

Background: Acute kidney injury (AKI) is a common complication in critically ill children. However, the common lack of baseline serum creatinine values affects AKI diagnosis and staging. Several approaches for...
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Role of bicarbonate and volume therapy in the prevention of acute kidney injury in rhabdomyolysis: a retrospective propensity score-matched cohort study

Kim HW, Kim S, Ohn JH, Kim NH, Lee J, Kim ES, Lim Y, Cho JH, Park HS, Ryu J, Kim Sw

Background: Although bicarbonate has traditionally been used to treat patients with rhabdomyolysis at high risk of acute kidney injury (AKI), it is unclear whether this is beneficial. This study compared...
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Olmesartan-associated Enteropathy with Acute Kidney Injury

Kang MJ, Min KH, Kim HW, Park SB, Kang DH, Choi CW, Kim SJ, Nam HS, Ryu DG

Olmesartan, a recently introduced angiotensin II receptor blocker for hypertension, has been reported to cause drug-induced small bowel enteropathy. The diagnosis of olmesartan-associated enteropathy (OAE) needs clinical suspicion and the...
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Additive harmful effects of acute kidney injury and acute heart failure on mortality in hospitalized patients

Son HE, Moon JJ, Park Jm, Ryu JY, Baek E, Jeong JC, Chin HJ, Na KY, Chae Dw, Han SS, Kim S

Background: Organ crosstalk between the kidney and the heart has been suggested. Acute kidney injury (AKI) and acute heart failure (AHF) are well-known independent risk factors for mortality in hospitalized...
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