Yeungnam Univ J Med.  2013 Dec;30(2):149-151.

A Case of Immunoglobulin A Nephropathy in a Patient with Kimura's Disease

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Pathology, School of Medicine, Catholic University of Daegu, Korea.
  • 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
  • 4Nephrology Division, Internal Medicine Department, National Health Institute Corporation, Ilsan Hospital, Goyang, Korea.
  • 5Nephrology Division, Internal Medicine Department, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. docbsk@yuhs.ac

Abstract

Kimura's disease is an angiolymphoid-proliferative disorder that manifests with benign subcutaneous swelling predominantly in the head and the neck. Kidney involvement, including proteinuria, occurs in 12-16% of patients with the disease, and 60-78% of such cases is nephrotic syndrome. Reported etiologies of nephrotic syndrome in Kimura's disease include membranous glomerulonephritis, mesangial proliferative glomerulonephritis, minimal-change disease, focal segmental glomerulosclerosis, diffuse proliferative glomerulonephritis and immunoglobulin A (IgA) nephropathy. There have been only two case reports of IgA nephropathy in Kimura's disease, in 1998. In this report, we present a third case of IgA nephropathy associated with Kimura's disease.

Keyword

Glomerulonephritis; Immunoglobulin A; Angiolymphoid hyperplasia with eosinophilia; Proteinuria

MeSH Terms

Angiolymphoid Hyperplasia with Eosinophilia
Glomerulonephritis
Glomerulonephritis, IGA*
Glomerulonephritis, Membranous
Glomerulosclerosis, Focal Segmental
Head
Humans
Immunoglobulin A*
Immunoglobulins*
Kidney
Neck
Nephrotic Syndrome
Proteinuria
Immunoglobulin A
Immunoglobulins
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