J Korean Radiol Soc.  1994 Apr;30(4):605-611.

Usefulness of Dynamic Magnetic Resonance Imaging in Brain Tumors

• Kim JS
• Lee SM
• Joo YG
• Kim H
• Woo SK
• Lee HJ
• Suh SJ
• Zeon SK
• Takahashi

Abstract

PURPOSE
To investigate the usefulness of dynamic MR imaging in the differential diagnosis of brain tumors.
MATERIALS AND METHODS
Dynamic MR imaging was performed in 43 patients with histopathologically proved brain tumrs. Serial images were sequentially obtained every 30 seconds for 3--5 minutes with use of spin-echo technique(TR 200msec/TE 15msec) after rapid injection of Gd-DTPA in a dose of 0.1mmol/kg body weight. Dynamics of contrast enhancement of the brain tumors were analyzed visually and by the sequential contrast enhancement ratio(CER).
RESULTS
On the dynamic MR imaging, contrast enhancement pattern of the gliomas showed gradual increase in signal intensity(SI) till 180 seconds and usually had a longer time to peak of the CER. The SI of metastatic brain tumors increased steeply till 30 seconds and then rapidly or gradually decreased and the tumors had a shorter time to peak of the CER. Meningiomas showed a rapid ascent in SI till 30 to 60 seconds and then made a plateau or slight descent of the CER. Lymphomas and germinomas showed relatively rapid increase of Sl till 30 seconds and usually had a longer time peak of the CER.
CONCLUSION
Dynamic MR imaging with Gd-DTPA may lead to further information about the brain tumors as the sequential contrast enhancement pattern and CER parameters seem to be helpful in discriminating among the brain tumors.

MeSH Terms

Body Weight
Brain Neoplasms*
Brain*
Diagnosis, Differential
Gadolinium DTPA
Germinoma
Glioma
Humans
Lymphoma
Magnetic Resonance Imaging*
Meningioma
Gadolinium DTPA