Korean J Vet Res.
2019 Dec;59(4):219-222. 10.14405/kjvr.2019.59.4.219.
Nailbed malignant melanoma in three dogs
- KMID: 2470122
- DOI: http://doi.org/10.14405/kjvr.2019.59.4.219
Abstract
- Three 8-12-year-old male cocker spaniels presented with an appendicular mass accompanied by pain, inflammation, lameness, and loss of nail in the digits of the forelimb or hindlimb. A histological examination revealed dermal masses of the digit composed of numerous neoplastic cells with marked pleomorphism and high mitosis. The neoplastic cells showed a strong invasive tendency into the epidermis and adjacent bony tissues, such as distal phalanx. Immunohistochemistry of the neoplastic cells in three masses revealed positive reactions for Melan-A. These three dogs were diagnosed as nailbed malignant melanoma in the digit based on the history, clinical signs, and histopathologic features.
