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Eccrine Syringofibroadenoma Associated with Bowen's Disease: A Case Report and Review of the Literature

Lee JS, Park H, Yoon HS, Cho S

Eccrine syringofibroadenoma (ESFA) is a rare, benign adnexal neoplasm which usually manifests as a solitary nodule on the extremities of elderly patients. Few case reports have described an association between...
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Association between Recurrence and Survival Rates According to the Location of Gastric Gastrointestinal Stromal Tumor

Yu YJ, Kim TH, Oh JH, Chung WC

BACKGROUND/AIMS: This study aimed to evaluate the clinicopathological parameters of gastric gastrointestinal stromal tumors (GISTs) and to investigate the effect of tumor site on clinical outcomes. MATERIALS AND METHODS: Patients treated...
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Correlations between embryo morphokinetic development and maternal age: Results from an intracytoplasmic sperm injection program

Faramarzi , Khalili MA, Mangoli E

OBJECTIVE: It is widely accepted that aging decreases women’s fertility capacity. The aim of this study was to assess correlations between maternal age and the morphokinetic parameters and cleavage pattern...
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Frozen Cytology of Meningeal Malignant Solitary Fibrous Tumor/Hemangiopericytoma

Kang M, Kim NR, Chung DH, Yie GT

A 51-year-old woman presented with severe dizziness. The brain magnetic resonance image revealed a 5.5 cm multiloculated mass with a thick rim in the left temporal lobe. Cytological examination of...
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Nailbed malignant melanoma in three dogs

Three 8-12-year-old male cocker spaniels presented with an appendicular mass accompanied by pain, inflammation, lameness, and loss of nail in the digits of the forelimb or hindlimb. A histological examination...
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Fine-Needle Aspiration Cytology of Carcinosarcoma in the Salivary Gland: An Extremely Rare Case Report

An HJ, Baek HJ, Kim JP, Kim MH, Song DH

Carcinosarcoma of the salivary gland is an extremely rare tumor that is composed of both malignant epithelial and mesenchymal components. Diagnosing carcinosarcoma with fine-needle aspiration cytology is challenging because of...
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An Intrarenal Adrenocortical Carcinoma Arising in an Adrenal Rest

Lee JH, Choi YD, Cho NH

We describe a case of a 61-year-old Korean man who was diagnosed with renal cell carcinoma that was discovered on abdominopelvic computed tomography obtained after the patient complained of back...
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CKAP2 phosphorylation by CDK1/cyclinB1 is crucial for maintaining centrosome integrity

Yoo BH, Kang DS, Park CH, Kang K, Bae CD

Previously, we have reported that CKAP2 is involved in the maintenance of centrosome integrity, thus allowing for proper mitosis in primary hepatocytes. To understand this biological process, we identified the...
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Antitumor Effect of KX-01 through Inhibiting Src Family Kinases and Mitosis

Kim S, Min A, Lee KH, Yang Y, Kim TY, Lim JM, Park SJ, Nam HJ, Kim JE, Song SH, Han SW, Oh DY, Kim JH, Kim TY, Hangauer D, Lau JY, Im K, Lee DS, Bang YJ, Im SA

PURPOSE: KX-01 is a novel dual inhibitor of Src and tubulin. Unlike previous Src inhibitors that failed to show clinical benefit during treatment of breast cancer, KX-01 can potentially overcome...
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Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells

Ndolo KM, Park KR, Lee HJ, Yoon KB, Kim YC, Han SY

Aurora kinase A plays an essential role in mitosis including chromosome separation and cytokinesis. Aberrant expression and activity of Aurora kinase A is associated with numerous malignancies including colorectal cancer...
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Glandular papilloma of the lung with malignant transformation

Sung WJ

Glandular papilloma of the lung is one of three histologic types of solitary endobronchial papillomas. It is known as an uncommon benign neoplasm. No malignant glandular papillomas have been reported....
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Diagnostic Significance of Cellular Neuroglial Tissue in Ovarian Immature Teratoma

Chai Y, Woo CG, Kim JY, Kim CJ, Khang SK, Kim J, Park IA, Kim EN, Kim KR

BACKGROUND: Immature teratoma (IT) is a tumor containing immature neuroectodermal tissue, primarily in the form of neuroepithelial tubules. However, the diagnosis of tumors containing only cellular neuroglial tissue (CNT) without...
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Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma

Koh HM, Jang BG, Hyun CL, Kim YS, Hyun JW, Chang WY, Maeng YH

BACKGROUND: Aurora kinase A (AURKA), or STK15/BTAK, is a member of the serine/threonine kinase family and plays important roles in mitosis and chromosome stability. This study investigated the clinical significance...
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A Case of Intravascular Papillary Endothelial Hyperplasia of Eyelid

Kim JY, Lee MK, Kim HY

PURPOSE: To report a case of intravascular papillary endothelial hyperplasia of the eyelid. CASE SUMMARY: A 30-year-old male presented with a right upper eyelid mass, which had been growing in size...
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The Predictive Value of Pathologic Features in Pituitary Adenoma and Correlation with Pituitary Adenoma Recurrence

Kim JS, Lee YS, Jung MJ, Hong YK

BACKGROUND: The 2004 World Health Organization classification introduced atypical pituitary adenoma (aPA), which was equivocally defined as invasion with increased mitotic activity that had a Ki-67 labeling index (LI) greater...
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Case of Pleomorphic Dermal Sarcoma of the Eyelid Treated with Micrographic Surgery and Secondary Intention Healing

Kim JI, Choi YJ, Seo HM, Kim HS, Lim JY, Kim DH, Chae SW, Lee GY, Kim WS

Pleomorphic dermal sarcoma (PDS) is a rare mesenchymal neoplasm sharing histopathological features with atypical fibroxanthoma (AFX), but has additional features of deep invasion of the superficial subcutis, tumor necrosis and...
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Nodular Fasciitis as a Pseudosarcomatous Lesion in the Ligamentum Nuchae: A Case Report

Kim SH, Kim JS, Nam KH

STUDY DESIGN: A case report. OBJECTIVES: Nodular fasciitis is a non-neoplastic soft-tissue lesion located in the deep subcutaneous region; it may be misdiagnosed as a malignant tumor due to its rapid...
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Tarantula cubensis extract alters the degree of apoptosis and mitosis in canine mammary adenocarcinomas

Gultiken N, Guvenc T, Kaya D, Agaoglu AR, Ay SS, Kucukaslan I, Emre B, Findik M, Schafer-Somi S, Aslan S

In the present study, 13 clinical cases of canine mammary adenocarcinoma were evaluated in order to understand the effect of Tarantula cubensis extract (TCE) on tumor tissue. Punch biopsies were...
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Determination of Mother Centriole Maturation in CPAP-Depleted Cells Using the Ninein Antibody

Lee M, Rhee K

BACKGROUND: Mutations in centrosomal protein genes have been identified in a number of genetic diseases in brain development, including microcephaly. Centrosomal P4.1-associated protein (CPAP) is one of the causal genes...
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A Case of Malignant Hidroacanthoma Simplex

Kim DW, Woo SH, Kim JI, Hwang SR, Rhee CH, Park J, Yun SK, Kim HU

  • KMID: 1789610
  • Korean J Dermatol.
  • 2015 Mar;53(3):226-229.
Malignant transformation of hidroacanthoma simplex into in situ porocarcinoma, also known as hidroacanthoma simplex with invasive growth, is very rare. Malignant hidroacanthoma simplex generally arises in the elderly and occurs...
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