Korean J Intern Med.  2019 Nov;34(6):1272-1278. 10.3904/kjim.2017.428.

Mortality of patients with chronic obstructive pulmonary disease: a nationwide population-based cohort study

Affiliations
  • 1Division of Pulmonology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
  • 2Department of Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Policy Research Affairs, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
  • 4Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 5Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 6Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
  • 7Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. ysamkim@yuhs.ac

Abstract

BACKGROUND/AIMS
Chronic obstructive pulmonary disease (COPD) is a major cause of mortality in the world. There are no population-based studies on long-term mortality in COPD patients in Korea.
METHODS
Using the large, population-based, National Health Insurance Service- National Sample Cohort (NHIS-NSC), we identified COPD patients using the International Classification of Disease-Tenth Revision (ICD-10) and prescription details in the NHIS-NSC during 2003 to 2013. We analyzed the survival curves of COPD patients by sex, age, and cause of death.
RESULTS
A total of 14,127 individuals older than 40 years were diagnosed with COPD. There were a total of 3,695 deaths (26.2%) in COPD patients during the study period. The 5-year mortality of COPD patients was 25.4% (29.9% in males and 19.1% in females). The mortality rate increased rapidly with age. The most common cause of death in COPD was chronic lower respiratory disease.
CONCLUSIONS
This study described long-term mortality in COPD patients in Korea. Higher mortality was observed in males, and it was closely related to age.

Keyword

Pulmonary disease, chronic obstructive; Mortality; Cause of death

MeSH Terms

Cause of Death
Classification
Cohort Studies*
Humans
Korea
Male
Mortality*
National Health Programs
Prescriptions
Pulmonary Disease, Chronic Obstructive*
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