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Cut-off value of FEV1/FEV6 to determine airflow limitation using handheld spirometry in subjects with risk of chronic obstructive pulmonary disease

Hwang YI, Kim Y, Rhee CK, Kim DK, Park YB, Yoo KH, Jung KS, Lee CY

Background/Aims: Postbronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) less than 0.7 using spirometry is the golden standard to diagnose airf low limitation of chronic obstructive pulmonary...
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Sputum Inflammometry to Manage Chronic Obstructive Pulmonary Disease Exacerbations: Beyond Guidelines

Venegas C, Zhao N, Ho T, Nair P

Quantitative sputum cytometry facilitates in assessing the nature of bronchitis associated with exacerbations of chronic obstructive pulmonary disease (COPD). This is not assessed in most clinical trials that evaluate the...
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Clinical Features of Chronic Obstructive Pulmonary Disease with High Fractional Exhaled Nitric Oxide

Ahn S, Kim TO, Chang J, Shin HJ, Kwon YS, Lim SC, Kim YI

Background: The fractional exhaled nitric oxide (FENO) test is useful in asthma patients. However, a few studies on its usefulness in chronic obstructive pulmonary disease (COPD) patients have been reported....
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Recent Advances in Molecular Basis of Lung Aging and Its Associated Diseases

Kang MJ

Aging is often viewed as a progressive decline in fitness due to cumulative deleterious alterations of biological functions in the living system. Recently, our understanding of the molecular mechanisms underlying...
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Role of phosphodiesterase-4 inhibitors in chronic obstructive pulmonary disease

Rhee CK, Kim DK

Phosphodiesterase-4 inhibitors (PDE4Is) are potent anti-inf lammatory agents and roflumilast has been used to prevent acute exacerbation of chronic obstructive pulmonary disease (COPD). Roflumilast decreases neutrophil migration, restores cystic fibrosis...
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Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease: Highly Effective but Often Overlooked

Arnold MT, Dolezal BA, Cooper CB

Patients with chronic obstructive pulmonary disease receive a range of treatments including but not limited to inhaled bronchodilators, inhaled and systemic corticosteroids, supplemental oxygen, and pulmonary rehabilitation. Pulmonary rehabilitation is...
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Comparisons of the Characteristics for Non-hospitalized, Hospitalized, and Rehospitalized Patients due to Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Choi JY, Yun SY

PURPOSE: This study compares the characteristics of patients with Chronic Obstructive Pulmonary Disease (COPD) according to hospitalization frequency due to Acute Exacerbation (AE) using a retrospective medical records review. METHODS: From...
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Utility of Computed Tomography in a Differential Diagnosis for the Patients with an Initial Diagnosis of Chronic Obstructive Pulmonary Disease Exacerbation

Park HJ, Kim SH, Kim HC, Lee BY, Lee SW, Lee JS, Lee SD, Seo JB, Oh YM

BACKGROUND: The utility of computed tomography (CT) in the differential diagnosis of patients with chronic obstructive pulmonary disease (COPD) exacerbation remains uncertain. However, due to the low cost associated with...
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Metabolic Syndrome in South Korean Patients with Chronic Obstructive Pulmonary Disease: A Focus on Gender Differences

Kim J, Yoo JY, Kim HS

PURPOSE: This study investigated the relationship between chronic obstructive pulmonary disease (COPD) and metabolic syndrome (MetS), focusing on gender differences and using large-scale data on the Korean general population. METHODS: The...
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Left ventricular dysfunction in relation with systemic inflammation in chronic obstructive pulmonary disease patients

Gulen ST, Eryilmaz U, Yilmaz M, Karadag F

BACKGROUND/AIMS: Most important cause of mortality in chronic obstructive pulmonary disease (COPD) patients is known to be cardiovascular disease (CVD). The objective of the present study was to evaluate the...
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Pharmacotherapy for chronic obstructive pulmonary disease

Jo YS, Park YB

Appropriate pharmacologic therapy can reduce symptoms and risk and severity of exacerbations, as well as improve the health status and exercise tolerance of patients with chronic obstructive pulmonary disease. The...
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Meta-analysis of the Effect of a Pulmonary Rehabilitation Program on Respiratory Muscle Strength in Patients with Chronic Obstructive Pulmonary Disease

Lee EN, Kim MJ

PURPOSE: Pulmonary rehabilitation (PR) programs are important in the treatment of patients with chronic obstructive pulmonary disease (COPD) but vary widely in type, duration, and efficacy. This meta-analysis investigated the...
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Risk Factors for Nutritional Status in Patients with Chronic Obstructive Pulmonary Disease

Jang JH, Min HS, Park JH

PURPOSE: The purpose of this study was to identify the characteristics of nutritional status and its risk factors in patients with Chronic Obstructive Pulmonary Disease (COPD). METHODS: Participants included 136 patients...
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Mortality of patients with chronic obstructive pulmonary disease: a nationwide population-based cohort study

Park SC, Kim DW, Park EC, Shin CS, Rhee CK, Kang YA, Kim YS

BACKGROUND/AIMS: Chronic obstructive pulmonary disease (COPD) is a major cause of mortality in the world. There are no population-based studies on long-term mortality in COPD patients in Korea. METHODS: Using the...
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Correlation between Physical Activity and Lung Function in Dusty Areas: Results from the Chronic Obstructive Pulmonary Disease in Dusty Areas (CODA) Cohort

Han Y, Heo Y, Hong Y, Kwon SO, Kim WJ

BACKGROUND: Although physical activity is known to be beneficial to lung function, few studies have been conducted to investigate the correlation between physical activity and lung function in dusty areas....
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Association between blood pressure, inflammation and spirometry parameters in chronic obstructive pulmonary disease

Arslan S, Yildiz G, Özdemir L, Kaysoydu E, Özdemir B

BACKGROUND/AIMS: Many systems including the cardiovascular system (ischemic heart diseases, heart failure, and hypertension) may act as comorbidities that can be seen during the course of chronic obstructive pulmonary disease...
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Factors Associated with Indacaterol Response in Tuberculosis-Destroyed Lung with Airflow Limitation

Kim TH, Rhee CK, Oh YM

BACKGROUND: Pulmonary tuberculosis can result in anatomical sequelae, and cause airflow limitation. However, there are no treatment guidelines for patients with a tuberculosis-destroyed lung. Recently, indacaterol effectiveness in chronic obstructive...
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Direct and Indirect Costs of Chronic Obstructive Pulmonary Disease in Korea

Kim C, Kim Y, Yang DW, Rhee CK, Kim SK, Hwang YI, Park YB, Lee YM, Jin S, Park J, Hahm CR, Park CH, Park SY, Jung CK, Kim YI, Lee SH, Yoon HK, Lee JH, Lim SY, Yoo KH

BACKGROUND: Understanding the burden of disease is important to establish cost-effective treatment strategies and to allocate healthcare resources appropriately. However, little reliable information is available regarding the overall economic burden...
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Risk Factors for Unawareness of Obstructive Airflow Limitation among Adults with Chronic Obstructive Pulmonary Disease

Jo M, Oh H

PURPOSE: The purpose of the present study is to examine risk factors for unawareness of obstructive airflow limitation among adults with chronic obstructive pulmonary disease. METHODS: Secondary data analysis was performed...
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Treatment and prevention of acute exacerbation of chronic obstructive pulmonary disease

Lim SY, Kim HJ, Ra SW, Lee JH, Kim TH

Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined as an acute aggravation of the patient's respiratory symptoms, particularly cough, sputum production, and dyspnea, which requires a change of...
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