Tuberc Respir Dis.  2014 Oct;77(4):155-160. 10.4046/trd.2014.77.4.155.

Chronic Obstructive Pulmonary Disease: Respiratory Review of 2014

• Lee YM

• KMID: 2320571
• DOI: http://doi.org/10.4046/trd.2014.77.4.155

Abstract

Chronic obstructive pulmonary disease (COPD) is characterized by a diverse array of pulmonary and nonpulmonary manifestations, but our understanding of COPD pathogenesis and the factors that influence its heterogeneity in disease presentation is poor. Despite this heterogeneity, treatment algorithms are primarily driven by a single measurement, forced expiratory volume in 1 second (FEV1) as a percentage of its predicted value (FEV1%). In 2011, a major shift in Global Initiative for Chronic Obstructive Lung Disease (GOLD) treatment recommendations was proposed that stratifies patients with COPD on the basis of symptoms and exacerbation history. This article reviews the work reported in 2013 that enlightens our understanding of COPD with respect to COPD classification systems, phenotype, biomarker, exacerbation, and management for patients with COPD.

Keyword

Pulmonary Disease, Chronic Obstructive; Pulmonary Disease, Chronic Obstructive; Review

MeSH Terms

Classification
Forced Expiratory Volume
Humans
Phenotype
Population Characteristics
Pulmonary Disease, Chronic Obstructive*

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