Ann Clin Microbiol.  2019 Jun;22(2):50-54. 10.5145/ACM.2019.22.2.50.

Facklamia hominis Isolated from a Wound: A Case Report and Review of the Literature

Affiliations
  • 1Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea. jeannie@snu.ac.kr
  • 2Department of Laboratory Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.

Abstract

Facklamia hominis is a facultative anaerobic Gram-positive coccus generally displaying weak alpha-hemolysis and negativity for catalase and oxidase. Facklamia species are part of the normal flora of the female genitourinary tract and have been reported in invasive diseases such as meningitis and infective endocarditis, albeit rarely. A 67 year-old-man presented to hospital with a tender, erythematous epidermal cyst on the right side of his upper back. Simple excision of the cyst was performed and the pus was taken with a sterile swab for culture, yielding no growth. One week later, discharge was observed in the patient's wound site and a sterile swab for culture was taken. The colonies grown were identified as F. hominis by the Vitek 2 system (bioMérieux, France), and the result was then reported to clinicians, and later confirmed by 16S rRNA gene sequencing and matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry. To the best of our knowledge, this is the first reported case of F. hominis isolation from a clinical specimen in Korea.

Keyword

16S rRNA gene sequencing; Facklamia hominis; Wound

MeSH Terms

Catalase
Endocarditis
Epidermal Cyst
Female
Genes, rRNA
Humans
Korea
Mass Spectrometry
Meningitis
Oxidoreductases
Suppuration
Wounds and Injuries*
Catalase
Oxidoreductases

Reference

1. Parvataneni KC, Iyer S, Khatib R, Saravolatz LD. Facklamia species and Streptococcus pneumoniae meningitis: a case report and review of the literature. Open Forum Infect Dis. 2015; 2:ofv029.
Article
2. Collins MD, Falsen E, Lemozy J, Akervall E, Sjödén B, Lawson PA. Phenotypic and phylogenetic characterization of some Globicatella-like organisms from human sources: description of Facklamia hominis gen. nov., sp. nov. Int J Syst Bacteriol. 1997; 47:880–882.
3. Collins MD, Lawson PA, Monasterio R, Falsen E, Sjöden B, Facklam RR. Facklamia ignava sp. nov., isolated from human clinical specimens. J Clin Microbiol. 1998; 36:2146–2148.
4. Lawson PA, Collins MD, Falsen E, Sjöden B, Facklam RR. Facklamia languida sp. nov., isolated from human clinical specimens. J Clin Microbiol. 1999; 37:1161–1164.
5. Collins MD, Hutson RA, Falsen E, Sjödén B. Facklamia sourekii sp. nov., isolated from human sources. Int J Syst Bacteriol. 1999; 49:635–638.
6. Hoyles L, Foster G, Falsen E, Thomson LF, Collins MD. Facklamia miroungae sp. nov., from a juvenile southern elephant seal (Mirounga leonina). Int J Syst Evol Microbiol. 2001; 51:1401–1403.
7. Collins MD, Hutson RA, Falsen E, Sjödén B. Facklamia tabacinasalis sp. nov., from powdered tobacco. Int J Syst Bacteriol. 1999; 49:1247–1250.
8. Ananthakrishna R, Shankarappa RK, Jagadeesan N, Math RS, Karur S, Nanjappa MC. Infective endocarditis: a rare organism in an uncommon setting. Case Rep Infect Dis. 2012; 2012:307852.
Article
9. Safavi S, Tufnell M, Bhalla A. Multi-territory ischaemic strokes and subacute bacterial endocarditis. BMJ Case Rep. 2010; 2010:bcr0620092023.
Article
10. Corona PS, Haddad S, Andrés J, González-López JJ, Amat C, Flores X. Case report: first report of a prosthetic joint infection caused by Facklamia hominis. Diagn Microbiol Infect Dis. 2014; 80:338–340.
11. Abat C, Garcia V, Rolain JM. Facklamia hominis scapula abscess, Marseille, France. New Microbes New Infect. 2015; 9:13–14.
12. Pérez Alonso AJ, Husein-El Ahmed H, Del Olmo Rivas C, Caballero Marcos L, Pérez Ramon JA. Facklamia sourekii necrotizing gangrene. Med Mal Infect. 2012; 42:283–284.
13. CLSI. Performance standards for antimicrobial susceptibility testing. CLSI document M100. Wayne, PA: Clinical and Laboratory Standards Institute;2016.
14. Rahmati E, Martin V, Wong D, Sattler F, Petterson J, Ward P, et al. Facklamia species as an underrecognized pathogen. Open Forum Infect Dis. 2017; 4:ofw272.
15. Petti CA, Polage CR, Schreckenberger P. The role of 16S rRNA gene sequencing in identification of microorganisms misidentified by conventional methods. J Clin Microbiol. 2005; 43:6123–6125.
Article
16. LaClaire L. Antimicrobial susceptibilities and clinical sources of Facklamia species. Antimicrob Agents Chemother. 2000; 44:2130–2132.
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