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A screening method for neuroblastoma and organic acidemias by gas chromatography-mass spectrometry

Jang HG, Park SK, Chun BC, Park J

  • KMID: 1686793
  • J Korean Soc Endocrinol.
  • 1992 Sep;7(3):280-287.
No abstract available.
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Quantitative analysis of endogenous steroids in human urine by using gas chromatography-mass spectrometry

Jang HG, Eom KD, Yoo YS, Chung BC, Park J

  • KMID: 1686656
  • J Korean Soc Endocrinol.
  • 1991 Sep;6(3):238-244.
No abstract available.
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Mass spectrometry based cellular phosphoinositides profiling and phospholipid analysis: A brief review

Kim Y, Shanta SR, Zhou LH, Kim KP

Phospholipids are key components of cellular membrane and signaling. Among cellular phospholipids, phosphoinositides, phosphorylated derivatives of phosphatidylinositol are important as a participant in essential metabolic processes in animals. However, due...
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Recommendations for the Use of Liquid Chromatography-Mass Spectrometry in the Clinical Laboratory: Part I. Implementation and Management

Lee K, Moon SY, Kim S, Choi HJ, Lee SG, Park HD, Lee SY, Song SH, Clinical Mass Spectrometry Research Committee of the Korean Society of Clinical Chemistry

Many types of assays involving mass spectrometry have been developed and applied in clinics. However, mass spectrometry has not been widely implemented yet relative to other measurement methods, including biochemical...
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Mass Spectrometry Analysis for Nitration of Proteins

Kim KP

Various proteomics and immunological methods including mass spectrometry combined with both liquid and 2-D PAGE, and immunodetection have been employed to identify and characterize nitrated proteins from pathological samples. Nitrosative...
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Urine Proteomics in the Era of Mass Spectrometry

Beasley-Green A

With the technological advances of mass spectrometry (MS)-based platforms, clinical proteomics is one of the most rapidly growing areas in biomedical research. Urine proteomics has become a popular subdiscipline of...
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Identification of Novel Metabolic Proteins Released by Insulin Signaling of the Rat Hypothalmus Using Liquid Chromatography-Mass Spectrometry (LC-MS)

Chin C

OBJECTIVE: The brain is dependent on glucose as an energy source. Intricate homeostatic mechanisms have been implicated in maintaining the blood glucose concentration in the brain. The aim of this...
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MALDI-TOF-MS Fingerprinting Provides Evidence of Urosepsis caused by Aerococcus urinae

Kim J, Hong SK, Kim M, Yong D, Lee K

Urosepsis due to Aerococcus urinae is rare in clinical settings with only a few of reported cases worldwide by 16S rRNA sequencing. Here we report a case of sepsis caused...
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Neuropeptidomics: Mass Spectrometry-Based Identification and Quantitation of Neuropeptides

Lee JE

Neuropeptides produced from prohormones by selective action of endopeptidases are vital signaling molecules, playing a critical role in a variety of physiological processes, such as addiction, depression, pain, and circadian...
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Application of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Imaging Mass Spectrometry (MALDI-TOF IMS) for Premalignant Gastrointestinal Lesions

Ko KH, Kwon CI, Park SH, Han NY, Lee HK, Kim EH, Hahm KB

  • KMID: 2165420
  • Clin Endosc.
  • 2013 Nov;46(6):611-619.
Imaging mass spectrometry (IMS) is currently receiving large attention from the mass spectrometric community, although its use is not yet well known in the clinic. As matrix-assisted laser desorption/ionization time-of-flight...
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A Case of Maple Syrup Urine Disease detected by Tandem Mass Spectrometry in Newborn Screening Test

O CG, Jung YS, Yoo BH, Lee DK, Lim IS

  • KMID: 2188691
  • J Korean Soc Neonatol.
  • 2003 May;10(1):88-93.
Maple syrup urine disease (MSUD) is an autosomal recessive disorder. Impaired activity of the branched-chain 2-oxo acid dehydrogenase complex causes accumulation of branched-chain L-amino and 2-oxo acid that can exert...
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Screening newborns for metabolic disorders based on targeted metabolomics using tandem mass spectrometry

Yoon HR

The main purpose of newborn screening is to diagnose genetic, metabolic, and other inherited disorders, at their earliest to start treatment before the clinical manifestations become evident. Understanding and tracing...
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Isolated 3-Methylcrotonyl CoA Carboxylase Deficiency Detected by Newborn Screening Program Using Tandem Mass Spectrometry

Kwak JY, Park JY, Nam KA, Son SH, Seo SS

  • KMID: 2278634
  • Korean J Pediatr.
  • 2005 May;48(5):561-564.
Isolated deficiency of 3-methylcrotonyl CoA carboxylase is a rare disorder of the catabolic pathway for leucine and many patients have mild symptoms or no symptom. However, the introduction of tandem...
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Cortisol Measurements in Cushing's Syndrome: Immunoassay or Mass Spectrometry?

Casals G, Hanzu FA

Determination of cortisol levels in the urine (24 hours urine free cortisol), saliva (late-night), or serum (total cortisol after dexamethasone suppression) is recommended to screen for Cushing's syndrome (CS). This...
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Performance of Matrix-Assisted Laser Desorption Ionization Time-of-Fight Mass Spectrometry for Rapid Discrimination of Methicillin-Resistant Staphylococcus aureus (MRSA): First Report of a Relation Between Protein Peaks and MRSA spa Type

Kwon SS, Hong SK, Kim MS, Yong D, Lee K

No abstract available.
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Analysis of para-chloroaniline after chemical interaction between alexidine and sodium hypochlorite using mass spectrometry: A preliminary study

Kim HS, Han SH, Oh S, Lim SM, Gu Y, Kum KY

The purposes of this study were firstly to investigate the any formation of precipitate after interaction between ALX and NaOCL and secondarily to analyze the PCA formation by using time...
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Comparison of Serum Zinc Levels Measured by Inductively Coupled Plasma Mass Spectrometry in Preschool Children with Febrile and Afebrile Seizures

Lee JH, Kim JH

BACKGROUND: Changes in levels of trace elements have been proposed to underlie febrile seizures. Particularly, low zinc levels have been proposed as related factor of febrile seizure. In this study,...
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Comparison between Source-induced Dissociation and Collision-induced Dissociation of Ampicillin, Chloramphenicol, Ciprofloxacin, and Oxytetracycline via Mass Spectrometry

Lee SH, Choi DW

  • KMID: 2317823
  • Toxicol Res.
  • 2013 Jun;29(2):107-114.
Mass spectrometry (MS) is a very powerful instrument that can be used to analyze a wide range of materials such as proteins, peptides, DNA, drugs, and polymers. The process typically...
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Two Cases of Campylobacter jejuni Bacteremia from Patients with Diarrhea

Han MS, Kim M, Lee Y, Yong D, Lee K

Campylobacter jejuni commonly causes bacterial enteritis but rarely causes extraintestinal infection including bacteremia. We isolated C. jejuni from the blood culture of a 20-year-old man presenting with fever and headache...
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Mass spectrometry based proteomic analysis of human stem cells: a brief review

Choi MY, An YJ, Kim SH, Roh SH, Ju HK, Hong SS, Park JH, Cho KJ, Choi DW, Kwon SW

  • KMID: 1091063
  • Exp Mol Med.
  • 2007 Dec;39(6):690-695.
Stem cells can give rise to various cell types and are capable of regenerating themselves over multiple cell divisions. Pluripotency and self-renewal potential of stem cells have drawn vast interest...
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