Korean J Pancreas Biliary Tract.  2017 Jul;22(3):123-126. 10.15279/kpba.2017.22.3.123.

Treatment of Autoimmune Pancreatitis

• Han J

• KMID: 2448606
• DOI: http://doi.org/10.15279/kpba.2017.22.3.123

Abstract

Autoimmune pancreatitis is a rare type of chronic pancreatitis. Unlike chronic pancreatitis caused by other causes, autoimmune pancreatitis is characterized by a dramatic response to corticosteroid and immunomodulator therapy. Two most widely used drugs for treatment of autoimmune pancreatitis are corticosteroid and immunomodulators. Corticosteroid is the first line drug for autoimmune pancreatitis and used for remission induction. Remission induction rate of corticosteroid therapy is more than 90%, but relapse rate is approximately 30%. Centers in Japan and Republic of Korea prefer low-dose corticosteroid for maintenance. On the other hand, centers in North America and Europe prefer immunomodulators for maintenance. In the future, well-designed studies on methods to decrease relapse rate of autoimmune pancreatitis and effective use of immunomodulators are needed.

Keyword

Pancreatitis; Chronic; Autoimmune diseases; Autoimmune pancreatitis; Drug therapy; Corticosteroids

MeSH Terms

Adrenal Cortex Hormones
Autoimmune Diseases
Drug Therapy
Europe
Hand
Immunologic Factors
Japan
North America
Pancreatitis*
Pancreatitis, Chronic
Recurrence
Remission Induction
Republic of Korea
Adrenal Cortex Hormones
Immunologic Factors