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Laparoscopic pancreatic neck transection and double pancreatico-jejunostomy, an alternative surgical approach to chronic pancreatitis

Cruz CJ, Kang I, Lee WJ, Kang CM

Chronic pancreatitis is a benign inflammatory process that results symptoms pertaining to loss of endocrine and exocrine function. Pain poses a great challenge in the management of CP and intractable...
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Endoscopic Management of Pancreatobiliary Stricture in Chronic Pancreatitis

Kim YS, Cho JH

Chronic pancreatitis is a debilitating disease with complications such as pancreatobiliary ductal stricture, leakage or fistulae contributing to significant morbidity and mortality. Treatment aims to relieve symptoms of pancreatobiliary ductal...
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Management Algorithm of Pancreatic Calculi

Jang DK, Lee JK

Pancreatic calculi associated with chronic pancreatitis lead to severe abdominal pain, which significantly reduces the quality of life of patients. Pancreatic calculi, especially those that obstruct the main pancreatic duct...
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A Case of 47-Years-Old Female with Obstructive Jaundice and Weight Loss

Park PG, Kang H, Chung MJ, Park JY, Bang S, Park SW, Song SY, Lee HS

Serine protease inhibitor Kazal-type 1 (SPINK1) is a gene expressed from pancreatic acinar cell which its mutation is known to be associated with chronic pancreatitis (CP) and pancreatic cancer. We...
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Immunoglobulin G4-Related Gastric Ulcer Mimicking Advanced Stomach Cancer in a Patient with Type I Autoimmune Pancreatitis

Park JH, Noh JH, Lee JH, Lee G, Hong SM, Cho KB, Kim MH

Type I autoimmune pancreatitis (AIP), a form of chronic pancreatitis, is included within the spectrum of immunoglobulin G4-related diseases (IgG4-RD). IgG4-RD can involve the salivary glands, bile ducts, kidneys and...
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Sex and Gender Medicine in Pancreatobiliary Diseases

Park SM

Sex and gender medicine investigates the impact of sex and gender differences on normal conditions, pathogenesis, and clinical features of diseases. By considering sex and gender differences during diagnosis, treatment...
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Recurrent Pancreatitis Caused by Afferent Loop Syndrome with Pathologic Features of Type II Autoimmune Pancreatitis

Lee SH, Kim MH, Kim HI, Back JY, Park YE, Hong SM, Kim HJ

Afferent loop syndrome (ALS) is a rare cause of recurrent pancreatitis. Recurrent pancreatitis in association with ALS can develop due to impaired outflow of pancreatic juice or reflux of enteric...
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The Utility of Endoscopic Ultrasound in Patients with Isolated Elevations in Serum Amylase and/or Lipase

Sitaraman , Sachdev AH, Gonda TA, Sethi A, Poneros JM, Gress FG

BACKGROUND/AIMS: The aim of this study was to describe the diagnostic yield of endoscopic ultrasound (EUS) in patients with isolated elevated levels of amylase and/or lipase. METHODS: A retrospective chart review...
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Recent advances in the diagnosis and management of chronic pancreatitis

Kwon CI, Cho JH, Choi SH, Ko KH, Tirkes T, Gromski MA, Lehman GA

Chronic pancreatitis is a chronic condition characterized by pancreatic inflammation that causes fibrosis and the destruction of exocrine and endocrine tissues. Chronic pancreatitis is a progressive disease, and no physiological...
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Docosahexaenoic Acid Inhibits Expression of Fibrotic Mediators in Mice With Chronic Pancreatitis

Lee S, Jeong YK, Lim JW, Kim H

BACKGROUND: Chronic pancreatitis (CP) is an irreversible progressive disease that destroys exocrine parenchyma, which are replaced by fibrous tissue. As pancreatic fibrosis is a key feature of CP, reducing fibrotic...
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Stage 1A Pancreatic Cancer Initially Manifesting as Clinical Acute Pancreatitis

Yoo DR, Kim J, Baek SH, Lee J, Nam SH, Lee SH, Kim MH

Pancreatic cancer has a poor prognosis due to the difficulty of early diagnosis. Observation is recommended for early diagnosis of pancreatic cancer in elderly patients with risk factors such as...
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Frey's procedure for chronic pancreatitis: a 10-year single-center experience in Korea

Kim HS, Lee JH, Park JS, Yoon DS

PURPOSE: Chronic pancreatitis (CP) is progressive inflammatory disease that leads to irreversible destruction of the pancreatic parenchyma. The main indications for surgical intervention in cases involving CP are intractable pain,...
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Predictive Value of Localized Stenosis of the Main Pancreatic Duct for Early Detection of Pancreatic Cancer

Kanno Y, Koshita S, Ogawa T, Kusunose H, Masu K, Sakai T, Yonamine K, Kawakami Y, Fujii Y, Miyamoto K, Murabayashi T, Kozakai F, Horaguchi , Noda Y, Oikawa M, Okada T, Ito K

BACKGROUND/AIMS: In this study, we aimed to evaluate the predictive value of localized stenosis of the main pancreatic duct (MPD) for early detection of pancreatic cancer. METHODS: Among 689 patients who...
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The drain fluid amylase level on the first postoperative day predicts pancreatic fistula in chronic pancreatitis patients undergoing Frey procedure

Pavankumar V, Kalayarasan R, Gnanasekaran S, Pottakkat

BACKGROUNDS/AIMS: Abdominal drains are routinely placed following Frey procedure for chronic pancreatitis (CP) despite the low incidence of pancreatic fistula (PF). The utility of the first postoperative day (POD1) drain...
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Endoscopic Management of Pancreaticopleural Fistula in a Child with Hereditary Pancreatitis

Lee D, Lee EJ, Kim JW, Moon JS, Kim YT, Ko JS

Pancreaticopleural fistula (PPF) a fistulous connection between the pancreas and pleural space due to prolonged chronic pancreatitis (CP). PPF is a very rare complication which presents in 0.4% of chronic...
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Treatment of Pancreatic Fluid Collections

Yoon SB, Chang JH, Lee IS

Pancreatic Fluid Collection (PFC) develops as a result of acute pancreatitis, chronic pancreatitis, trauma, and postoperation. Although percutaneous drainage, surgery and Endoscopic Retrograde Panceatogram are used as conventional treatments in...
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Laparoscopic Longitudinal Pancreaticojejunostomy for Chronic Obstructive Pancreatitis

Chong EH, Lee JW, Choi SH

PURPOSE: Longitudinal pancreaticojejunostomy is a treatment option for selected patients with chronic obstructive pancreatitis that is rarely performed laparoscopically. METHODS: A 54-year-old man presented with chronic postprandial abdominal pain. A computed...
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The Role of Genetic Mutation in the Pathogenesis of Pancreatitis

Paik WH, Jang DK, Lee JK

10–30% of patients with pancreatitis can be categorized as idiopathic pancreatitis, and some of them may be due to genetic alterations. Since hereditary pancreatitis develops from pediatric patients with symptoms...
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Groove Pancreatitis: Endoscopic Treatment via the Minor Papilla and Duct of Santorini Morphology

Chantarojanasiri T, Isayama H, Nakai Y, Matsubara , Yamamoto N, Takahara N, Mizuno S, Hamada T, Kogure H, Koike K

BACKGROUND/AIMS: Groove pancreatitis (GP) is an uncommon disease involving the pancreaticoduodenal area. Possible pathogenesis includes obstructive pancreatitis in the duct of Santorini and impaired communication with the duct of Wirsung,...
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Advanced Therapeutic Gastrointestinal Endoscopy in Children – Today and Tomorrow

Nabi Z, Reddy DN

Gastrointestinal (GI) endoscopy plays an indispensable role in the diagnosis and management of various pediatric GI disorders. While the pace of development of pediatric GI endoscopy has increased over the...
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