Korean J Pancreas Biliary Tract.  2017 Apr;22(2):57-62. 10.15279/kpba.2017.22.2.57.

Etiology and Diagnosis of Chronic Pancreatitis

Affiliations
  • 1Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
  • 2Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. drjaihwan@snu.ac.kr

Abstract

Chronic pancreatitis is an irreversible inflammatory disease of the pancreas characterized by progressive inflammation and fibrosis resulting in loss of exocrine and endocrine function. Chronic pancreatitis is a wide spectrum of fibro-inflammatory disorders of the pancreas that includes calcifying, obstructive, and steroid-responsive form. Chronic pancreatitis without specific comment generally refers to calcifying or obstructive chronic pancreatitis. The well-known traditional causes of chronic pancreatitis are alcohol and smoking. Recently, environmental effects and the importance of genes such as genetic variation or interaction have been highlighted. Computerized tomography or magnetic resonance cholangiopancreatography have been used for diagnosis of chronic pancreatitis. However, endoscopic ultrasound has been recently used for diagnosis, too.

Keyword

Pancreatitis; chronic; Etiology; Diagnosis

MeSH Terms

Cholangiopancreatography, Magnetic Resonance
Diagnosis*
Fibrosis
Genetic Variation
Inflammation
Pancreas
Pancreatitis
Pancreatitis, Chronic*
Smoke
Smoking
Ultrasonography
Smoke
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