Gut Liver.  2008 Jun;2(1):1-7.

Treatment and Relapse of Autoimmune Pancreatitis

Affiliations
  • 1Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. mhkim@amc.seoul.kr

Abstract

Autoimmune pancreatitis (AIP) is a peculiar type of chronic pancreatitis whose pathogenesis involves autoimmune mechanisms. The steroid responsiveness has a significant impact on the diagnosis of AIP because patients with AIP and pancreatic cancer share many clinical features. This review focuses on the treatment and relapse of AIP. The goal of AIP treatment is remission of symptoms, serology, radiologic changes, or histology, which also applies to relapse. Although it is generally agreed that steroids should be offered to AIP patients with active disease, there is no standardized steroid regimen for AIP and no consensus on the dose and duration of steroid induction and tapering schedule, and optimal duration and dose of maintenance therapy. Obtaining a consensus on the optimal treatment regimen is very important to reducing the relapse rate. In this review, we discuss the treatment regimens used in many centers.

Keyword

Autoimmune pancreatitis; Treatment; Relapse

MeSH Terms

Appointments and Schedules
Consensus
Humans
Pancreatic Neoplasms
Pancreatitis
Pancreatitis, Chronic
Recurrence
Steroids
Steroids
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