Korean J Gastroenterol.  2019 Apr;73(4):207-212. 10.4166/kjg.2019.73.4.207.

Prevalence of Functional Gastrointestinal Disorders in School Children and Adolescents

• Peralta-Palmezano JJ
• Guerrero-Lozano R

• KMID: 2443633
• DOI: http://doi.org/10.4166/kjg.2019.73.4.207

Abstract

BACKGROUND/AIMS
The epidemiology of functional gastrointestinal disorders (FGIDs) in developed and developing countries involves a high prevalence of constipation and irritable bowel syndrome. This study examined the prevalence of functional gastrointestinal disorders in schoolchildren and adolescents in Colombia using the Rome III criteria.
METHODS
A cross-sectional study was performed on Colombian children between 8 and 17 years old. The Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version self-report form was answered by students from two schools. The prevalence of FGID was calculated and correlation tests were conducted among the variables analyzed.
RESULTS
A total of 864 children with a mean age of 12.5±2.5 years were analyzed; 50.7% were female. Two hundred and fifty-nine children (30%) had at least one FGID, and of these, 163 were female (62.9%). Sixty-nine children had two or more FGIDs (8%). Functional constipation was the most prevalent disorder (13.2%), followed in order by abdominal migraine (8.3%), irritable bowel syndrome (6.9%), and aerophagia (3.1%). A significantly higher prevalence of FGID was observed in females (p=0.000). No significant difference was observed between the age groups or type of school they attended.
CONCLUSIONS
The overall prevalence of FGID in the sample was 30%, with functional constipation being the most common. These results are similar to those of other prevalence studies reported elsewhere.

Keyword

Constipation; Developing countries; Epidemiology; Irritable bowel syndrome; Schools

MeSH Terms

Adolescent*
Child*
Colombia
Constipation
Cross-Sectional Studies
Developing Countries
Epidemiology
Female
Gastrointestinal Diseases*
Humans
Irritable Bowel Syndrome
Migraine Disorders
Prevalence*

Reference

1. Drossman DA. Functional gastrointestinal disorders and the Rome IV Process. In : Drossman DA, Chang L, Chey WD, Kellow J, Tack J, Whitehead WE, editors. ROME IV functional pediatric gastrointestinal disorders: disorders of gut-brain interaction. 1st ed. Raleigh: The Rome Foundation Inc.;2017. p. 2–32.

2. Játiva E, Velasco-Benítez CA, Koppen IJ, Játiva-Cabezas Z, Saps M. Prevalence of functional gastrointestinal disorders in schoolchildren in ecuador. J Pediatr Gastroenterol Nutr. 2016; 63:25–28.

3. Saps M, Nichols-Vinueza DX, Rosen JM, Velasco-Benítez CA. Prevalence of functional gastrointestinal disorders in Colombian school children. J Pediatr. 2014; 164:542–545.e1.

4. Zablah R, Velasco-Benítez CA, Merlos I, Bonilla S, Saps M. Prevalence of functional gastrointestinal disorders in school-aged children in El Salvador. Rev Gastroenterol Mex. 2015; 80:186–191.

5. Dhroove G, Saps M, Garcia-Bueno C, Leyva Jiménez A, Rodriguez-Reynosa LL, Velasco-Benítez CA. Prevalence of functional gastrointestinal disorders in Mexican schoolchildren. Rev Gastroenterol Mex. 2017; 82:13–18.

6. Lu PL, Saps M, Chanis RA, Velasco-Benítez CA. The prevalence of functional gastrointestinal disorders in children in Panama: a school-based study. Acta Paediatr. 2016; 105:e232–e236.

7. Sagawa T, Okamura S, Kakizaki S, Zhang Y, Morita K, Mori M. Functional gastrointestinal disorders in adolescents and quality of school life. J Gastroenterol Hepatol. 2013; 28:285–290.

8. Bhatia V, Deswal S, Seth S, Kapoor A, Sibal A, Gopalan S. Prevalence of functional gastrointestinal disorders among adolescents in Delhi based on Rome III criteria: a school-based survey. Indian J Gastroenterol. 2016; 35:294–298.

9. Devanarayana NM, Adhikari C, Pannala W, Rajindrajith S. Prevalence of functional gastrointestinal diseases in a cohort of Sri Lankan adolescents: comparison between Rome II and Rome III criteria. J Trop Pediatr. 2011; 57:34–39.

10. Lewis ML, Palsson OS, Whitehead WE, van Tilburg MAL. Prevalence of functional gastrointestinal disorders in children and adolescents. J Pediatr. 2016; 177:39–43.e3.

11. Hyams JS, Burke G, Davis PM, Rzepski B, Andrulonis PA. Abdominal pain and irritable bowel syndrome in adolescents: a community-based study. J Pediatr. 1996; 129:220–226.

12. Gulewitsch MD, Enck P, Schwille-Kiuntke J, Weimer K, Schlarb AA. Rome III criteria in parents' hands: pain-related functional gastrointestinal disorders in community children and associations with somatic complaints and mental health. Eur J Gastroenterol Hepatol. 2013; 25:1223–1229.

13. Udoh E, Devanarayana NM, Rajindrajith S, Meremikwu M, Benninga MA. Abdominal pain-predominant functional gastrointestinal disorders in adolescent nigerians. J Pediatr Gastroenterol Nutr. 2016; 62:588–593.

14. Rouster AS, Karpinski AC, Silver D, Monagas J, Hyman PE. Functional gastrointestinal disorders dominate pediatric gastroenterology outpatient practice. J Pediatr Gastroenterol Nutr. 2016; 62:847–851.

15. Talachian E, Bidari A, Zahmatkesh H. Abdominal pain-related functional gastrointestinal disorders based on Rome III criteria in a pediatric gastroenterology clinic. Med J Islam Repub Iran. 2015; 29:247. eCollection 2015.

16. Velasco CA, Nichols-Vinueza D, Saps M. Spanish version of the questionnaire on pediatric gastrointestinal symptoms-Rome III (QPGSRIII). J Pediatr Gastroenterol Nutr. 2011; 53:Suppl 1. E65.

17. Saps M, Velasco CA, Nichols-Vinueza D. Validation of the Rome III criteria. High internal consistency of the questionnaire of pediatric gastrointestinal symptoms (Spanish version). J Pediatr Gastroenterol Nutr. 2012; 55:Suppl 1. E36–E37.

18. Boronat AC, Ferreira-Maia AP, Matijasevich A, Wang YP. Epidemiology of functional gastrointestinal disorders in children and adolescents: a systematic review. World J Gastroenterol. 2017; 23:3915–3927.

19. Helgeland H, Flagstad G, Grøtta J, Vandvik PO, Kristensen H, Markestad T. Diagnosing pediatric functional abdominal pain in children (4-15 years old) according to the Rome III criteria: results from a Norwegian prospective study. J Pediatr Gastroenterol Nutr. 2009; 49:309–315.

20. Baber KF, Anderson J, Puzanovova M, Walker LS. Rome II versus Rome III classification of functional gastrointestinal disorders in pediatric chronic abdominal pain. J Pediatr Gastroenterol Nutr. 2008; 47:299–302.

21. Devanarayana NM, Mettananda S, Liyanarachchi C, et al. Abdominal pain-predominant functional gastrointestinal diseases in children and adolescents: prevalence, symptomatology, and association with emotional stress. J Pediatr Gastroenterol Nutr. 2011; 53:659–665.

22. Saps M, Sztainberg M, Pusatcioglu C, Chogle A. Tu2007 Accuracy of diagnosis for abdominal migraine in children. Gastroenterology. 2014; 146:Suppl 1. S897.

23. Devanarayana NM, Rajindrajith S. Aerophagia among Sri Lankan schoolchildren: epidemiological patterns and symptom characteristics. J Pediatr Gastroenterol Nutr. 2012; 54:516–520.

24. Chitkara DK, Bredenoord AJ, Rucker MJ, Talley NJ. Aerophagia in adults: a comparison with functional dyspepsia. Aliment Pharmacol Ther. 2005; 22:855–858.