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Dietary modulation of gut microbiota for the relief of irritable bowel syndrome

Kim MY, Choi SW

Irritable bowel syndrome (IBS) is a frequently diagnosed gastrointestinal (GI) disorder characterized by recurrent abdominal pain, bloating, and changes in the stool form or frequency without any structural changes and...
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Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome

Liu G, Li S, Chen N, Zhao Z, Guo M, Liu H, Feng J, Zhang D, Yao Z, Hu B

  • KMID: 2517537
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):426-435.
  • doi: 10.5056/jnm20134
Background/Aims Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disease characterized by recurrent abdominal pain and bowel dysfunction. However, the majority of previous neuroimaging studies focus on brain structure and...
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Emergence of Celiac Disease and Gluten-related Disorders in Asia

Mohta S, Rajput MS, Ahuja V, Makharia GK

  • KMID: 2517527
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):337-346.
  • doi: 10.5056/jnm20140
Celiac disease (CeD) is a systemic, immune-mediated enteropathy, which is triggered by gluten protein in genetically susceptible individuals. CeD, once thought to be an uncommon disease, is now recognized to...
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Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches

Thein W, Po WW, Choi WS, Sohn UD

The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the...
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Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine

Jalanka J, Lam C, Bennett A, Hartikainen A, Crispie F, Finnegan LA, Cotter PD, Spiller R

  • KMID: 2514686
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):279-291.
  • doi: 10.5056/jnm20205
Background/Aims Diarrhea-predominant irritable bowel syndrome (IBS-D) has been previously associated with evidence of immune activation and altered microbiota. Our aim is to assess the effect of the anti-inflammatory agent, mesalazine, on...
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A Resting-state Functional Magnetic Resonance Imaging Study of Whole-brain Functional Connectivity of Voxel Levels in Patients With Irritable Bowel Syndrome With Depressive Symptoms

Li J, He P, Lu X, Guo Y, Liu M, Li G, Ding J

  • KMID: 2514683
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):248-256.
  • doi: 10.5056/jnm20209
Background/Aims Depressive symptom is one of the most common symptoms in patients with irritable bowel syndrome (IBS), but its pathogenetic mechanisms remain unclear. As a voxel-level graph theory analysis method, degree...
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Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia

Wang C, Fang X

  • KMID: 2514672
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):153-164.
  • doi: 10.5056/jnm20175
Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional gastrointestinal disorders (FGIDs) and account for a large proportion of consulting patients. These 2 disorders overlap with each other...
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Lactose Sensitivity and Lactose Malabsorption: The 2 Faces of Lactose Intolerance

Bouchoucha M, Fysekidis M, Rompteaux P, Raynaud JJ, Sabate JM, Benamouzig R

  • KMID: 2514684
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):257-264.
  • doi: 10.5056/jnm20094
Background/Aims Self-reported lactose intolerance (LI) is frequent in patients with functional bowel disorders (FBD) that could be interpreted as irritable bowel syndrome (IBS). The present study aims to characterize the responses...
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Compositional and Functional Changes in the Gut Microbiota in Irritable Bowel Syndrome Patients

Lee SM, Kim N, Yoon H, Kim YS, Choi SI, Park JH, Lee DH

Background/Aims: This study aimed to characterize the changes in the gut microbiota of irritable bowel syndrome (IBS) patients and to investigate the consequent alterations in bacterial functions. Methods: We performed 16S...
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Effects of Health Disorder Signals on Irritable Bowel Syndrome and Urination Disorders: Focusing on Door-to-Door Salespeople and Women Who have Experienced Symptoms of Irritable Bowel Syndrome

Lee W, Cho DY, Choi SH

Purpose: This study investigated the effects of Health Disorder Signals on irritable bowel syndrome (IBS) and urination disorders, and the relationship between IBS and urination disorders. Methods: A questionnaire survey...
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Internet Survey of Japanese Patients With Chronic Constipation: Focus on Correlations Between Sleep Quality, Symptom Severity, and Quality of Life

Yamamoto S, Kawamura Y, Yamamoto K, Yamaguchi Y, Tamura Y, Izawa S, Nakagawa H, Wakita Y, Hijikata Y, Ebi M, Funaki Y, Ohashi W, Ogasawara N, Sasaki M, Maekawa M, Kasugai K

  • KMID: 2521164
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):602-611.
  • doi: 10.5056/jnm20135
Background/Aims Chronic constipation and lifestyle factors can affect sleep quality. We evaluated the relationship between chronic constipation and sleep in the Japanese population. Methods This cross-sectional internet-based survey included 3000 subjects with constipation,...
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Perceived Gastrointestinal Symptoms and Association With Meals in a French Cohort of Patients With Irritable Bowel Syndrome

Melchior C, Fremaux S, Jouët P, Macaigne G, Raynaud JJ, Facon S, Iglicki F, Taes Y, Sabate JM

  • KMID: 2521158
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):574-580.
  • doi: 10.5056/jnm20201
Background/Aims The aim of our study is to evaluate the association between meals and perceived gastrointestinal symptoms in real life in a French cohort of irritable bowel syndrome (IBS) patients. Methods This prospective...
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Adherence to Dietary Approaches to Stop Hypertension Eating Plan and Prevalence of Irritable Bowel Syndrome in Adults

Soltani S, Keshteli AH, Esmaillzadeh A, Adibi P

  • KMID: 2510065
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):78-86.
  • doi: 10.5056/jnm20007
Background/Aims Despite huge evidence on the link between adherence to dietary approaches to stop hypertension (DASH) eating pattern and several metabolic abnormalities, the association of this diet with irritable bowel syndrome...
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Gut Microbial Dysbiosis in the Pathogenesis of Gastrointestinal Dysmotility and Metabolic Disorders

Singh R, Zogg H, Wei L, Bartlett A, Ghoshal UC, Rajender S, Ro S

  • KMID: 2510059
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):19-34.
  • doi: 10.5056/jnm20149
Of all microorganisms in the human body, the largest and most complex population resides in the gastrointestinal (GI) tract. The gut microbiota continuously adapts to the host environment and serves...
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A Meta-Analysis on the Effects of Mind-Body Therapy on Patients with Irritable Bowel Syndrome

Choi EH, Kim MJ, Lee EN

Purpose: Previous randomized controlled trials (RCT) found that mind-body therapy can improve the health outcomes of patients with irritablebowel syndrome (IBS). The purpose of this meta-analysis was to identify the...
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The Effects of a Motivation-Enhanced Self-Management Program for Female College Students with Irritable Bowel Syndrome

Back JY, Jun SE

Purpose: The purpose of this study was to develop a motivation-enhanced self-management (MESM) intervention for irritable bowel syndrome (IBS) and to evaluate its effects on female college students with IBS....
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Model Predicting Irritable Bowel Syndrome Severity in University Students

Park BH, Lee KS

Purpose: The purpose of this study was to build and verify a structural model that could predict the severity of irritable bowel syndrome in university students. Methods: Participants were 205 students...
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Atopic Patients Who Fulfilled Rome III Criteria for Irritable Bowel Syndrome Had Higher Animal Danders Sensitization

Siah KTH, Santosa A, Cheung CKY, Soh AYS, Bigliardi

  • KMID: 2500684
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):267-273.
  • doi: 10.5056/jnm19181
Background/Aims The relationship between animal exposure and irritable bowel syndrome (IBS) is debated. Epidemiological studies have shown that atopy is more prevalent in IBS patients and vice versa. We set...
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The effects of three novel probiotics isolated from the Korean fermented food Kimchi on the stress-induced defecation of rats

Kim MJ, Min YW, Lee C, Jang YS, Kim CH, Chang DK

Purpose: The interest in novel probiotics that improve symptoms of irritable bowel syndrome (IBS) has been growing trend. This study aims to investigate the probiotic effect of three kinds of...
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Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome

Chung HG, Min YW, Lee C, Hong SN, Won JY, Jang JA, Kim CH, Chang DK

BACKGROUND/AIMS: Dysbiosis is an important factor in the pathogenesis of irritable bowel syndrome (IBS). Several studies have reported promising results using probiotics for the treatment of IBS. This study evaluated...
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